Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study
This is the peer reviewed version of the following article: Småbrekke, B., Rinde, L.B.R., Mathisen Hald, E.M., Njølstad, I., Mathiesen, E.B., Johnsen, S.H., . Lijfering, W.M. (2017). Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study. Journal...
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Online Access: | https://hdl.handle.net/10037/14764 https://doi.org/10.1111/jth.13858 |
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ftunivtroemsoe:oai:munin.uit.no:10037/14764 2023-05-15T18:34:24+02:00 Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study Småbrekke, Birgit Rinde, Ludvig Balteskard Mathisen Hald, Erin Njølstad, Inger Mathiesen, Ellisiv B. Johnsen, Stein Harald Hansen, John-Bjarne Brækkan, Sigrid Kufaas Lijfering, Willem M. 2017-10-05 https://hdl.handle.net/10037/14764 https://doi.org/10.1111/jth.13858 eng eng Wiley Småbrekke, B. (2019). Shared risk factors for arterial cardiovascular diseases and venous thromboembolism. (Doctoral thesis). https://hdl.handle.net/10037/15580. Journal of Thrombosis and Haemostasis Småbrekke, B., Rinde, L.B.R., Mathisen Hald, E.M., Njølstad, I., Mathiesen, E.B., Johnsen, S.H., . Lijfering, W.M. (2017). Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study. Journal of Thrombosis and Haemostasis, 16 (12), 2344-2351. https://doi.org/10.1111/jth.13858 FRIDAID 1541562 doi:10.1111/jth.13858 1538-7933 1538-7836 https://hdl.handle.net/10037/14764 openAccess VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Hematology: 775 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Hematologi: 775 atherosclerosis cohort studies repeated measurements risk factors venous thromboembolism Journal article Tidsskriftartikkel Peer reviewed 2017 ftunivtroemsoe https://doi.org/10.1111/jth.13858 2021-06-25T17:56:26Z This is the peer reviewed version of the following article: Småbrekke, B., Rinde, L.B.R., Mathisen Hald, E.M., Njølstad, I., Mathiesen, E.B., Johnsen, S.H., . Lijfering, W.M. (2017). Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study. Journal of Thrombosis and Haemostasis, 16 (12), 2344-2351, which has been published in final form at https://doi.org/10.1111/jth.13858 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Background : Whether a relationship between atherosclerosis and subsequent venous thromboembolism (VTE) exists is controversial. Objective : To investigate the association between carotid atherosclerosis and VTE by using repeated measurements of intima media thickness (IMT) and total plaque area (TPA) in participants recruited from the general population. Methods : Participants were recruited from the fourth (1994–1995), fifth (2001–2002) and sixth (2007–2008) surveys of the Tromsø Study. In total, 10 426 participants attended, for whom measurements of carotid IMT and TPA and potential confounders were updated at each available survey. Time‐varying Cox regression models were used to calculate hazard ratios (HRs) of VTE across various levels of IMT and TPA adjusted for age, sex, and body mass index. Results : There were 368 incident VTE events during a median follow‐up of 10.8 years. Participants with increasing IMT were, on average, older and had a less favorable cardiovascular risk profile. There was no association between tertiles of increasing TPA and the risk of VTE in the time‐varying model, and increasing IMT was not associated with an increased risk of VTE (HR 0.96, 95% confidence interval [CI] 0.86–1.07). Neither plaque formation nor plaque progression was associated with the risk of VTE (respectively: HR 1.00, 95% CI 0.98–1.02; and HR 0.96, 95% CI 0.84–1.11). Conclusion : Carotid IMT and TPA were not associated with an increased risk of VTE in time‐varying analyses. Furthermore, there was no association between plaque initiation or plaque progression and subsequent VTE. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Tromsø Journal of Thrombosis and Haemostasis 15 12 2344 2351 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Hematology: 775 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Hematologi: 775 atherosclerosis cohort studies repeated measurements risk factors venous thromboembolism |
spellingShingle |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Hematology: 775 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Hematologi: 775 atherosclerosis cohort studies repeated measurements risk factors venous thromboembolism Småbrekke, Birgit Rinde, Ludvig Balteskard Mathisen Hald, Erin Njølstad, Inger Mathiesen, Ellisiv B. Johnsen, Stein Harald Hansen, John-Bjarne Brækkan, Sigrid Kufaas Lijfering, Willem M. Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study |
topic_facet |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Hematology: 775 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Hematologi: 775 atherosclerosis cohort studies repeated measurements risk factors venous thromboembolism |
description |
This is the peer reviewed version of the following article: Småbrekke, B., Rinde, L.B.R., Mathisen Hald, E.M., Njølstad, I., Mathiesen, E.B., Johnsen, S.H., . Lijfering, W.M. (2017). Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study. Journal of Thrombosis and Haemostasis, 16 (12), 2344-2351, which has been published in final form at https://doi.org/10.1111/jth.13858 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Background : Whether a relationship between atherosclerosis and subsequent venous thromboembolism (VTE) exists is controversial. Objective : To investigate the association between carotid atherosclerosis and VTE by using repeated measurements of intima media thickness (IMT) and total plaque area (TPA) in participants recruited from the general population. Methods : Participants were recruited from the fourth (1994–1995), fifth (2001–2002) and sixth (2007–2008) surveys of the Tromsø Study. In total, 10 426 participants attended, for whom measurements of carotid IMT and TPA and potential confounders were updated at each available survey. Time‐varying Cox regression models were used to calculate hazard ratios (HRs) of VTE across various levels of IMT and TPA adjusted for age, sex, and body mass index. Results : There were 368 incident VTE events during a median follow‐up of 10.8 years. Participants with increasing IMT were, on average, older and had a less favorable cardiovascular risk profile. There was no association between tertiles of increasing TPA and the risk of VTE in the time‐varying model, and increasing IMT was not associated with an increased risk of VTE (HR 0.96, 95% confidence interval [CI] 0.86–1.07). Neither plaque formation nor plaque progression was associated with the risk of VTE (respectively: HR 1.00, 95% CI 0.98–1.02; and HR 0.96, 95% CI 0.84–1.11). Conclusion : Carotid IMT and TPA were not associated with an increased risk of VTE in time‐varying analyses. Furthermore, there was no association between plaque initiation or plaque progression and subsequent VTE. |
format |
Article in Journal/Newspaper |
author |
Småbrekke, Birgit Rinde, Ludvig Balteskard Mathisen Hald, Erin Njølstad, Inger Mathiesen, Ellisiv B. Johnsen, Stein Harald Hansen, John-Bjarne Brækkan, Sigrid Kufaas Lijfering, Willem M. |
author_facet |
Småbrekke, Birgit Rinde, Ludvig Balteskard Mathisen Hald, Erin Njølstad, Inger Mathiesen, Ellisiv B. Johnsen, Stein Harald Hansen, John-Bjarne Brækkan, Sigrid Kufaas Lijfering, Willem M. |
author_sort |
Småbrekke, Birgit |
title |
Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study |
title_short |
Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study |
title_full |
Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study |
title_fullStr |
Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study |
title_full_unstemmed |
Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study |
title_sort |
repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the tromsø study |
publisher |
Wiley |
publishDate |
2017 |
url |
https://hdl.handle.net/10037/14764 https://doi.org/10.1111/jth.13858 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
Småbrekke, B. (2019). Shared risk factors for arterial cardiovascular diseases and venous thromboembolism. (Doctoral thesis). https://hdl.handle.net/10037/15580. Journal of Thrombosis and Haemostasis Småbrekke, B., Rinde, L.B.R., Mathisen Hald, E.M., Njølstad, I., Mathiesen, E.B., Johnsen, S.H., . Lijfering, W.M. (2017). Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study. Journal of Thrombosis and Haemostasis, 16 (12), 2344-2351. https://doi.org/10.1111/jth.13858 FRIDAID 1541562 doi:10.1111/jth.13858 1538-7933 1538-7836 https://hdl.handle.net/10037/14764 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1111/jth.13858 |
container_title |
Journal of Thrombosis and Haemostasis |
container_volume |
15 |
container_issue |
12 |
container_start_page |
2344 |
op_container_end_page |
2351 |
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1766219117947256832 |