Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study
Accepted manuscript version, licensed CC BY-NC-ND 4.0. Published version available at https://doi.org/10.1016/j.jad.2018.06.010 . Objective : Physical inactivity is a major public health problem associated with an increased risk of several psychiatric and physical conditions. This study investigated...
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ftunivtroemsoe:oai:munin.uit.no:10037/14559 2023-05-15T18:34:46+02:00 Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study Sheikh, Mashhood Ahmed 2018-06-05 https://hdl.handle.net/10037/14559 https://doi.org/10.1016/j.jad.2018.06.010 eng eng Elsevier Journal of Affective Disorders Sheikh, M.A. (2018). Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study. Journal of Affective Disorders , 238, 327-335. https://doi.org/10.1016/j.jad.2018.06.010 FRIDAID 1626181 doi:10.1016/j.jad.2018.06.010 0165-0327 1573-2517 https://hdl.handle.net/10037/14559 openAccess VDP::Medical disciplines: 700::Health sciences: 800 VDP::Medisinske Fag: 700::Helsefag: 800 Physical activity Tranquilizer Psychotropic Psychiatric morbidity Journal article Tidsskriftartikkel Peer reviewed 2018 ftunivtroemsoe https://doi.org/10.1016/j.jad.2018.06.010 2021-06-25T17:56:17Z Accepted manuscript version, licensed CC BY-NC-ND 4.0. Published version available at https://doi.org/10.1016/j.jad.2018.06.010 . Objective : Physical inactivity is a major public health problem associated with an increased risk of several psychiatric and physical conditions. This study investigated the association between leisure time physical activity (PA) and incident use of prescription tranquilizers in a regionally representative and prospective cohort. Methods : A total of 4043 men and women (mean age: 61.3 years; 57% women) from the Tromsø Study were followed for six years. Leisure time PA was captured at baseline. Psychiatric morbidity was measured by use of prescription tranquilizers, captured at both baseline and follow-up. Leisure time PA at baseline was used as a predictor of subsequent (incident) use of prescription tranquilizers. We used multinomial regression models and Poisson regression models to estimate relative risk-ratios (RRRs), and relative risks (RRs), respectively, and their corresponding 95% confidence intervals (CIs). Results : In the fully-adjusted model, accounting for socio-demographic factors, parental history of psychopathology, years of education, smoking, respondent's psychopathology at baseline, and occupational PA, a lower leisure time PA conferred a 41% increased risk of incident use of prescription tranquilizers at follow-up (RR = 1.41, 95% CI: 1.09, 1.83; p = 0.010). Conclusions : These findings suggest that physical inactivity increases the risk of psychiatric morbidity (albeit, measured via use of prescription tranquilizers). Future regionally representative and longitudinal research is required to confirm/refute our findings and explore underlying mechanisms. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Tromsø Journal of Affective Disorders 238 327 335 |
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University of Tromsø: Munin Open Research Archive |
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ftunivtroemsoe |
language |
English |
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VDP::Medical disciplines: 700::Health sciences: 800 VDP::Medisinske Fag: 700::Helsefag: 800 Physical activity Tranquilizer Psychotropic Psychiatric morbidity |
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VDP::Medical disciplines: 700::Health sciences: 800 VDP::Medisinske Fag: 700::Helsefag: 800 Physical activity Tranquilizer Psychotropic Psychiatric morbidity Sheikh, Mashhood Ahmed Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study |
topic_facet |
VDP::Medical disciplines: 700::Health sciences: 800 VDP::Medisinske Fag: 700::Helsefag: 800 Physical activity Tranquilizer Psychotropic Psychiatric morbidity |
description |
Accepted manuscript version, licensed CC BY-NC-ND 4.0. Published version available at https://doi.org/10.1016/j.jad.2018.06.010 . Objective : Physical inactivity is a major public health problem associated with an increased risk of several psychiatric and physical conditions. This study investigated the association between leisure time physical activity (PA) and incident use of prescription tranquilizers in a regionally representative and prospective cohort. Methods : A total of 4043 men and women (mean age: 61.3 years; 57% women) from the Tromsø Study were followed for six years. Leisure time PA was captured at baseline. Psychiatric morbidity was measured by use of prescription tranquilizers, captured at both baseline and follow-up. Leisure time PA at baseline was used as a predictor of subsequent (incident) use of prescription tranquilizers. We used multinomial regression models and Poisson regression models to estimate relative risk-ratios (RRRs), and relative risks (RRs), respectively, and their corresponding 95% confidence intervals (CIs). Results : In the fully-adjusted model, accounting for socio-demographic factors, parental history of psychopathology, years of education, smoking, respondent's psychopathology at baseline, and occupational PA, a lower leisure time PA conferred a 41% increased risk of incident use of prescription tranquilizers at follow-up (RR = 1.41, 95% CI: 1.09, 1.83; p = 0.010). Conclusions : These findings suggest that physical inactivity increases the risk of psychiatric morbidity (albeit, measured via use of prescription tranquilizers). Future regionally representative and longitudinal research is required to confirm/refute our findings and explore underlying mechanisms. |
format |
Article in Journal/Newspaper |
author |
Sheikh, Mashhood Ahmed |
author_facet |
Sheikh, Mashhood Ahmed |
author_sort |
Sheikh, Mashhood Ahmed |
title |
Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study |
title_short |
Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study |
title_full |
Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study |
title_fullStr |
Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study |
title_full_unstemmed |
Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study |
title_sort |
leisure time physical activity and incident use of prescription tranquilizers: a longitudinal population-based study |
publisher |
Elsevier |
publishDate |
2018 |
url |
https://hdl.handle.net/10037/14559 https://doi.org/10.1016/j.jad.2018.06.010 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
Journal of Affective Disorders Sheikh, M.A. (2018). Leisure time physical activity and incident use of prescription tranquilizers: A longitudinal population-based study. Journal of Affective Disorders , 238, 327-335. https://doi.org/10.1016/j.jad.2018.06.010 FRIDAID 1626181 doi:10.1016/j.jad.2018.06.010 0165-0327 1573-2517 https://hdl.handle.net/10037/14559 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1016/j.jad.2018.06.010 |
container_title |
Journal of Affective Disorders |
container_volume |
238 |
container_start_page |
327 |
op_container_end_page |
335 |
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1766219672344068096 |