Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure
Accepted manuscript version. Published version available at https://doi.org/10.1016/j.marenvres.2017.06.005 . Accepted manuscript version, licensed CC BY-NC-ND 4.0. Increasing anthropogenic activities in the Arctic pose the risk for accidental oil spills but our knowledge of ecotoxicological effects...
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Online Access: | https://hdl.handle.net/10037/13822 https://doi.org/10.1016/j.marenvres.2017.06.005 |
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ftunivtroemsoe:oai:munin.uit.no:10037/13822 2023-05-15T14:39:35+02:00 Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure Vieweg, Ireen Benedetti, Maura Lanzoni, Ilaria Regoli, Francesco Nahrgang, Jasmine 2017-06-13 https://hdl.handle.net/10037/13822 https://doi.org/10.1016/j.marenvres.2017.06.005 eng eng Elsevier Marine Environmental Research info:eu-repo/grantAgreement/RCN/FRIMEDBIO/214184/Norway/Polar cod, lipid metabolism and disruption by polycyclic aromatic hydrocarbons// info:eu-repo/grantAgreement/RCN/NORDSATS/195160/Norway/Northern Environmental Waste Management// Vieweg, I., Benedetti, M., Lanzoni, I., Regoli, F. & Nahrgang, J. (2017). Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure. Marine Environmental Research, 130, 48-59. https://doi.org/10.1016/j.marenvres.2017.06.005 FRIDAID 1490342 doi:10.1016/j.marenvres.2017.06.005 0141-1136 1879-0291 https://hdl.handle.net/10037/13822 openAccess VDP::Matematikk og naturvitenskap: 400 VDP::Mathematics and natural scienses: 400 Økotoksikologi / Ecotoxicology Fish Arctic Oil spills Oxidative stress Antioxidants Biotransformation Total oxyradical scavenging capacity Boreogadus saida Journal article Tidsskriftartikkel Peer reviewed 2017 ftunivtroemsoe https://doi.org/10.1016/j.marenvres.2017.06.005 2021-06-25T17:55:30Z Accepted manuscript version. Published version available at https://doi.org/10.1016/j.marenvres.2017.06.005 . Accepted manuscript version, licensed CC BY-NC-ND 4.0. Increasing anthropogenic activities in the Arctic pose the risk for accidental oil spills but our knowledge of ecotoxicological effects is still limited for Arctic organisms. This study aimed to provide insights in baseline levels of antioxidants in polar cod ( Boreogadus saida ) from different Arctic locations and investigate the susceptibility of this species to oxidative stress during a 32 day dietary crude oil exposure. Baseline levels of individual antioxidants and total oxyradical scavenging capacity (TOSC) varied among different Arctic fjords. Upon crude oil exposure, dose- and time-dependent polycyclic aromatic hydrocarbons (PAHs) biotransformation was evident through hepatic ethoxyresorufine-O-deethylase activity, glutathione S-transferase mRNA expression and biliary PAH metabolites. Changes in the activity of individual antioxidants and TOSC was, however, slight and transient upon exposure. In conclusion, biotransformation was clearly induced by the sub-lethal levels of crude oil in polar cod, while the antioxidant defense responded with high variability. Article in Journal/Newspaper Arctic Boreogadus saida polar cod University of Tromsø: Munin Open Research Archive Arctic Marine Environmental Research 130 48 59 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Matematikk og naturvitenskap: 400 VDP::Mathematics and natural scienses: 400 Økotoksikologi / Ecotoxicology Fish Arctic Oil spills Oxidative stress Antioxidants Biotransformation Total oxyradical scavenging capacity Boreogadus saida |
spellingShingle |
VDP::Matematikk og naturvitenskap: 400 VDP::Mathematics and natural scienses: 400 Økotoksikologi / Ecotoxicology Fish Arctic Oil spills Oxidative stress Antioxidants Biotransformation Total oxyradical scavenging capacity Boreogadus saida Vieweg, Ireen Benedetti, Maura Lanzoni, Ilaria Regoli, Francesco Nahrgang, Jasmine Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure |
topic_facet |
VDP::Matematikk og naturvitenskap: 400 VDP::Mathematics and natural scienses: 400 Økotoksikologi / Ecotoxicology Fish Arctic Oil spills Oxidative stress Antioxidants Biotransformation Total oxyradical scavenging capacity Boreogadus saida |
description |
Accepted manuscript version. Published version available at https://doi.org/10.1016/j.marenvres.2017.06.005 . Accepted manuscript version, licensed CC BY-NC-ND 4.0. Increasing anthropogenic activities in the Arctic pose the risk for accidental oil spills but our knowledge of ecotoxicological effects is still limited for Arctic organisms. This study aimed to provide insights in baseline levels of antioxidants in polar cod ( Boreogadus saida ) from different Arctic locations and investigate the susceptibility of this species to oxidative stress during a 32 day dietary crude oil exposure. Baseline levels of individual antioxidants and total oxyradical scavenging capacity (TOSC) varied among different Arctic fjords. Upon crude oil exposure, dose- and time-dependent polycyclic aromatic hydrocarbons (PAHs) biotransformation was evident through hepatic ethoxyresorufine-O-deethylase activity, glutathione S-transferase mRNA expression and biliary PAH metabolites. Changes in the activity of individual antioxidants and TOSC was, however, slight and transient upon exposure. In conclusion, biotransformation was clearly induced by the sub-lethal levels of crude oil in polar cod, while the antioxidant defense responded with high variability. |
format |
Article in Journal/Newspaper |
author |
Vieweg, Ireen Benedetti, Maura Lanzoni, Ilaria Regoli, Francesco Nahrgang, Jasmine |
author_facet |
Vieweg, Ireen Benedetti, Maura Lanzoni, Ilaria Regoli, Francesco Nahrgang, Jasmine |
author_sort |
Vieweg, Ireen |
title |
Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure |
title_short |
Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure |
title_full |
Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure |
title_fullStr |
Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure |
title_full_unstemmed |
Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure |
title_sort |
antioxidant defenses in polar cod (boreogadus saida) and responsiveness toward dietary crude oil exposure |
publisher |
Elsevier |
publishDate |
2017 |
url |
https://hdl.handle.net/10037/13822 https://doi.org/10.1016/j.marenvres.2017.06.005 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Boreogadus saida polar cod |
genre_facet |
Arctic Boreogadus saida polar cod |
op_relation |
Marine Environmental Research info:eu-repo/grantAgreement/RCN/FRIMEDBIO/214184/Norway/Polar cod, lipid metabolism and disruption by polycyclic aromatic hydrocarbons// info:eu-repo/grantAgreement/RCN/NORDSATS/195160/Norway/Northern Environmental Waste Management// Vieweg, I., Benedetti, M., Lanzoni, I., Regoli, F. & Nahrgang, J. (2017). Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure. Marine Environmental Research, 130, 48-59. https://doi.org/10.1016/j.marenvres.2017.06.005 FRIDAID 1490342 doi:10.1016/j.marenvres.2017.06.005 0141-1136 1879-0291 https://hdl.handle.net/10037/13822 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1016/j.marenvres.2017.06.005 |
container_title |
Marine Environmental Research |
container_volume |
130 |
container_start_page |
48 |
op_container_end_page |
59 |
_version_ |
1766311566657978368 |