The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study
This is the peer reviewed version of the following article: The All-Age Prevalence of Helicobacter pylori Infection andPotential Transmission Routes. A Population-Based Study, which has been published in final form at http://doi.org/10.1111/hel.1231 . This article may be used for non-commercial purp...
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2016
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Online Access: | https://hdl.handle.net/10037/12056 https://doi.org/10.1111/hel.12316 |
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ftunivtroemsoe:oai:munin.uit.no:10037/12056 2023-05-15T17:43:38+02:00 The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study Breckan, Ragnar K Paulssen, Eyvind Jakob Asfeldt, Anne Mette Kvamme, Jan-Magnus Straume, Bjørn Florholmen, Jon 2016-05-12 https://hdl.handle.net/10037/12056 https://doi.org/10.1111/hel.12316 eng eng John Wiley & Sons Ltd Helicobacter Breckan R.K., Paulssen E.J., Asfeldt A.M., Kvamme J, Straume B.K., Florholmen J. The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study. Helicobacter. 2016;21(6):586-595 FRIDAID 1415007 doi:10.1111/hel.12316 1083-4389 1523-5378 https://hdl.handle.net/10037/12056 openAccess Adolescents adults children population-based transmission Helicobacter pylori VDP::Medical disciplines: 700 Journal article Tidsskriftartikkel Peer reviewed 2016 ftunivtroemsoe https://doi.org/10.1111/hel.12316 2021-06-25T17:55:43Z This is the peer reviewed version of the following article: The All-Age Prevalence of Helicobacter pylori Infection andPotential Transmission Routes. A Population-Based Study, which has been published in final form at http://doi.org/10.1111/hel.1231 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Background and aims: Previous research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission. Methods: Subjects from all age groups (children 0–11 years, adolescents 12–17 years and adults ≥18 years of age), recruited from both an urban and a rural community in Northern Norway, were invited to provide stool samples for the diagnosis of H. pylori antigen and to fill in a questionnaire (adult and adolescents only) on gastrointestinal symptoms, lifestyle factors and biometric data. Results: A total of 1 624 (35.3%) of the invited subjects, including 173 (39.3%) of the children, 46 (19.2%) of the adolescents, and 1 416 (36.1%) of the adults, responded to the invitation. H. pylori infection was nearly undetectable (0.6%) among the children, whereas the prevalence increased from 20% in adolescents toward a peak of 45% in the highest age group. Univariate analyses of possible risk factors of H. pylori infection showed significant associations to private well water, the use of outhouse toilet, and having farm animals in childhood, but the associations waned in multivariate analyses. Conclusions: In our populations, with apparent high hygienic standards, the transmission of H. pylori infection may start not only in childhood, but also in adolescence, where potential transmission routes may be outdoor toilet use, private well water, and farm animals. Article in Journal/Newspaper Northern Norway University of Tromsø: Munin Open Research Archive Norway Helicobacter 21 6 586 595 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
Adolescents adults children population-based transmission Helicobacter pylori VDP::Medical disciplines: 700 |
spellingShingle |
Adolescents adults children population-based transmission Helicobacter pylori VDP::Medical disciplines: 700 Breckan, Ragnar K Paulssen, Eyvind Jakob Asfeldt, Anne Mette Kvamme, Jan-Magnus Straume, Bjørn Florholmen, Jon The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study |
topic_facet |
Adolescents adults children population-based transmission Helicobacter pylori VDP::Medical disciplines: 700 |
description |
This is the peer reviewed version of the following article: The All-Age Prevalence of Helicobacter pylori Infection andPotential Transmission Routes. A Population-Based Study, which has been published in final form at http://doi.org/10.1111/hel.1231 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Background and aims: Previous research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission. Methods: Subjects from all age groups (children 0–11 years, adolescents 12–17 years and adults ≥18 years of age), recruited from both an urban and a rural community in Northern Norway, were invited to provide stool samples for the diagnosis of H. pylori antigen and to fill in a questionnaire (adult and adolescents only) on gastrointestinal symptoms, lifestyle factors and biometric data. Results: A total of 1 624 (35.3%) of the invited subjects, including 173 (39.3%) of the children, 46 (19.2%) of the adolescents, and 1 416 (36.1%) of the adults, responded to the invitation. H. pylori infection was nearly undetectable (0.6%) among the children, whereas the prevalence increased from 20% in adolescents toward a peak of 45% in the highest age group. Univariate analyses of possible risk factors of H. pylori infection showed significant associations to private well water, the use of outhouse toilet, and having farm animals in childhood, but the associations waned in multivariate analyses. Conclusions: In our populations, with apparent high hygienic standards, the transmission of H. pylori infection may start not only in childhood, but also in adolescence, where potential transmission routes may be outdoor toilet use, private well water, and farm animals. |
format |
Article in Journal/Newspaper |
author |
Breckan, Ragnar K Paulssen, Eyvind Jakob Asfeldt, Anne Mette Kvamme, Jan-Magnus Straume, Bjørn Florholmen, Jon |
author_facet |
Breckan, Ragnar K Paulssen, Eyvind Jakob Asfeldt, Anne Mette Kvamme, Jan-Magnus Straume, Bjørn Florholmen, Jon |
author_sort |
Breckan, Ragnar K |
title |
The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study |
title_short |
The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study |
title_full |
The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study |
title_fullStr |
The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study |
title_full_unstemmed |
The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study |
title_sort |
all-age prevalence of helicobacter pylori infection and potential transmission routes. a population-based study |
publisher |
John Wiley & Sons Ltd |
publishDate |
2016 |
url |
https://hdl.handle.net/10037/12056 https://doi.org/10.1111/hel.12316 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Northern Norway |
genre_facet |
Northern Norway |
op_relation |
Helicobacter Breckan R.K., Paulssen E.J., Asfeldt A.M., Kvamme J, Straume B.K., Florholmen J. The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study. Helicobacter. 2016;21(6):586-595 FRIDAID 1415007 doi:10.1111/hel.12316 1083-4389 1523-5378 https://hdl.handle.net/10037/12056 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1111/hel.12316 |
container_title |
Helicobacter |
container_volume |
21 |
container_issue |
6 |
container_start_page |
586 |
op_container_end_page |
595 |
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1766145771151818752 |