Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings
Morbilliviruses are recognized as biological agents highly impacting the health and conservation status of free-ranging cetaceans worldwide, as clearly exemplified by the two Dolphin Morbillivirus (DMV) epidemics of 1990-1992 and 2006-2008 among Mediterranean striped dolphins (Stenella coeruleoalba)...
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Online Access: | http://hdl.handle.net/11575/80840 https://doi.org/10.1016/j.rvsc.2012.07.030 |
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ftunivteramo:oai:research.unite.it:11575/80840 2024-04-14T08:09:30+00:00 Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings DI GUARDO, Giovanni DI FRANCESCO, Cristina Esmeralda Eleni C Cocumelli C Scholl F Casalone C Peletto S Mignone W Tittarelli C Di Nocera F Leonardi L Fernández A Marcer F Mazzariol S. Yes DI GUARDO, Giovanni DI FRANCESCO, Cristina Esmeralda Eleni, C Cocumelli, C Scholl, F Casalone, C Peletto, S Mignone, W Tittarelli, C Di Nocera, F Leonardi, L Fernández, A Marcer, F Mazzariol, S. 2013 STAMPA http://hdl.handle.net/11575/80840 https://doi.org/10.1016/j.rvsc.2012.07.030 eng eng info:eu-repo/semantics/altIdentifier/pmid/PMID: 22921372 info:eu-repo/semantics/altIdentifier/wos/WOS:000319028000021 volume:94 issue:1 firstpage:132 lastpage:137 numberofpages:6 journal:RESEARCH IN VETERINARY SCIENCE http://hdl.handle.net/11575/80840 doi:10.1016/j.rvsc.2012.07.030 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84871511713 Morbillivirus infection Stranded cetacean Pathology Italy info:eu-repo/semantics/article 2013 ftunivteramo https://doi.org/10.1016/j.rvsc.2012.07.030 2024-03-21T15:30:25Z Morbilliviruses are recognized as biological agents highly impacting the health and conservation status of free-ranging cetaceans worldwide, as clearly exemplified by the two Dolphin Morbillivirus (DMV) epidemics of 1990-1992 and 2006-2008 among Mediterranean striped dolphins (Stenella coeruleoalba). After these two epidemics, morbilliviral infection (MI) cases with peculiar neurobiological features were reported in striped dolphins stranded along the Spanish coastline. Affected cetaceans showed a subacute-to-chronic, non-suppurative encephalitis, with brain lesions strongly resembling those found in human "subacute sclerosing panencephalitis" and "old dog encephalitis". Brain was the only tissue in which morbilliviral antigen and/or genome could be detected. Beside a case of morbilliviral encephalitis in a striped dolphin's calf stranded in 2009, we observed 5 additional MI cases in 2 striped dolphins, 1 bottlenose dolphin (Tursiops truncatus) and 2 fin whales (Balaenoptera physalus), all stranded in 2011 along the Italian coastline. Noteworthy, 3 of these animals (2 striped dolphins and 1 bottlenose dolphin) showed immunohistochemical (IHC) and/or biomolecular (PCR) evidence of morbilliviral antigen and/or genome exclusively in their brain, with 1 striped dolphin and 1 bottlenose dolphin also exhibiting a non-suppurative encephalitis. Furthermore, simultaneous IHC and PCR evidence of a Toxoplasma gondii coinfection was obtained in 1 fin whale. The above results are consistent with those reported in striped dolphins after the two MI epidemics of 1990-92 and 2006-2008, with evidence of morbilliviral antigen and/or genome being found exclusively in the brain tissue from affected animals. Article in Journal/Newspaper Balaenoptera physalus Fin whale IRIS Universita degli Studi di Teramo Research in Veterinary Science 94 1 132 137 |
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IRIS Universita degli Studi di Teramo |
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English |
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Morbillivirus infection Stranded cetacean Pathology Italy |
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Morbillivirus infection Stranded cetacean Pathology Italy DI GUARDO, Giovanni DI FRANCESCO, Cristina Esmeralda Eleni C Cocumelli C Scholl F Casalone C Peletto S Mignone W Tittarelli C Di Nocera F Leonardi L Fernández A Marcer F Mazzariol S. Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings |
topic_facet |
Morbillivirus infection Stranded cetacean Pathology Italy |
description |
Morbilliviruses are recognized as biological agents highly impacting the health and conservation status of free-ranging cetaceans worldwide, as clearly exemplified by the two Dolphin Morbillivirus (DMV) epidemics of 1990-1992 and 2006-2008 among Mediterranean striped dolphins (Stenella coeruleoalba). After these two epidemics, morbilliviral infection (MI) cases with peculiar neurobiological features were reported in striped dolphins stranded along the Spanish coastline. Affected cetaceans showed a subacute-to-chronic, non-suppurative encephalitis, with brain lesions strongly resembling those found in human "subacute sclerosing panencephalitis" and "old dog encephalitis". Brain was the only tissue in which morbilliviral antigen and/or genome could be detected. Beside a case of morbilliviral encephalitis in a striped dolphin's calf stranded in 2009, we observed 5 additional MI cases in 2 striped dolphins, 1 bottlenose dolphin (Tursiops truncatus) and 2 fin whales (Balaenoptera physalus), all stranded in 2011 along the Italian coastline. Noteworthy, 3 of these animals (2 striped dolphins and 1 bottlenose dolphin) showed immunohistochemical (IHC) and/or biomolecular (PCR) evidence of morbilliviral antigen and/or genome exclusively in their brain, with 1 striped dolphin and 1 bottlenose dolphin also exhibiting a non-suppurative encephalitis. Furthermore, simultaneous IHC and PCR evidence of a Toxoplasma gondii coinfection was obtained in 1 fin whale. The above results are consistent with those reported in striped dolphins after the two MI epidemics of 1990-92 and 2006-2008, with evidence of morbilliviral antigen and/or genome being found exclusively in the brain tissue from affected animals. |
author2 |
Yes DI GUARDO, Giovanni DI FRANCESCO, Cristina Esmeralda Eleni, C Cocumelli, C Scholl, F Casalone, C Peletto, S Mignone, W Tittarelli, C Di Nocera, F Leonardi, L Fernández, A Marcer, F Mazzariol, S. |
format |
Article in Journal/Newspaper |
author |
DI GUARDO, Giovanni DI FRANCESCO, Cristina Esmeralda Eleni C Cocumelli C Scholl F Casalone C Peletto S Mignone W Tittarelli C Di Nocera F Leonardi L Fernández A Marcer F Mazzariol S. |
author_facet |
DI GUARDO, Giovanni DI FRANCESCO, Cristina Esmeralda Eleni C Cocumelli C Scholl F Casalone C Peletto S Mignone W Tittarelli C Di Nocera F Leonardi L Fernández A Marcer F Mazzariol S. |
author_sort |
DI GUARDO, Giovanni |
title |
Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings |
title_short |
Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings |
title_full |
Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings |
title_fullStr |
Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings |
title_full_unstemmed |
Morbillivirus infection in cetaceans stranded along the Italian coastline: pathological, immunohistochemical and biomolecular findings |
title_sort |
morbillivirus infection in cetaceans stranded along the italian coastline: pathological, immunohistochemical and biomolecular findings |
publishDate |
2013 |
url |
http://hdl.handle.net/11575/80840 https://doi.org/10.1016/j.rvsc.2012.07.030 |
genre |
Balaenoptera physalus Fin whale |
genre_facet |
Balaenoptera physalus Fin whale |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/PMID: 22921372 info:eu-repo/semantics/altIdentifier/wos/WOS:000319028000021 volume:94 issue:1 firstpage:132 lastpage:137 numberofpages:6 journal:RESEARCH IN VETERINARY SCIENCE http://hdl.handle.net/11575/80840 doi:10.1016/j.rvsc.2012.07.030 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84871511713 |
op_doi |
https://doi.org/10.1016/j.rvsc.2012.07.030 |
container_title |
Research in Veterinary Science |
container_volume |
94 |
container_issue |
1 |
container_start_page |
132 |
op_container_end_page |
137 |
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1796306998773415936 |