Kinetics of the formation of substituted diamides of carbonic acid

• Main Author: Smythe, LE
• Format: Thesis
• Language: English
• Published: 1952
• Subjects: Carbon dioxide; Chemistry; Organic; Carbonic acid
• Online Access: https://eprints.utas.edu.au/21630/; https://eprints.utas.edu.au/21630/13/whole_Smythe_ex_pub_mat_thesis.pdf; https://eprints.utas.edu.au/21630/1/whole_SmytheLloydEarle1953_thesis.pdf; https://eprints.utas.edu.au/21630/2/whole_SmytheLloydEarle1953Vol2_thesis.pdf

A serious drawback which hindered the elucidation of many reaction mechanisms in organic chemistry, was the lack of accurate quantitative data. The classical investigation by Lapworth or the halogenation of ketones initiated a new kinetic era in organic chemistry promoting the search for more exact knowledge of reaction mechanisms and the energy considerations involved. The reaction between urea and formaldehyde first occupied the attention or chemists some sixty years ago with the studies of Holzer, Ludy, Hemmelmayr, Goldschmidt, Einhorn, Hamburger and others. The greater portion of the work published since then related to the preparative aspects of the reaction and it was not until 1928 that the first serious attempt to suggest a reaction mechanism was made.