Cell mediated immunity in Antarctic wintering personnel; 1984-1992
Cell-mediated immune responses were studied in 12 Antarctic and sub-Antarctic wintering groups at quarterly intervals over the period 1984-1992, using the cutaneous CMI Multitest. These populations are among the most isolated on earth. While the sub-Antarctic population at Macquarie Island had level...
Published in: | Immunology and Cell Biology |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Blackwell Publishing Asia
1995
|
Subjects: | |
Online Access: | https://doi.org/10.1038/icb.1995.48 http://www.ncbi.nlm.nih.gov/pubmed/7493767 http://ecite.utas.edu.au/5430 |
id |
ftunivtasecite:oai:ecite.utas.edu.au:5430 |
---|---|
record_format |
openpolar |
spelling |
ftunivtasecite:oai:ecite.utas.edu.au:5430 2023-05-15T13:56:40+02:00 Cell mediated immunity in Antarctic wintering personnel; 1984-1992 Muller, HK Lugg, DJ Quinn, D 1995 https://doi.org/10.1038/icb.1995.48 http://www.ncbi.nlm.nih.gov/pubmed/7493767 http://ecite.utas.edu.au/5430 en eng Blackwell Publishing Asia http://dx.doi.org/10.1038/icb.1995.48 Muller, HK and Lugg, DJ and Quinn, D, Cell mediated immunity in Antarctic wintering personnel; 1984-1992, Immunology and Cell Biology, 73, (4) pp. 316-320. ISSN 0818-9641 (1995) [Refereed Article] http://www.ncbi.nlm.nih.gov/pubmed/7493767 http://ecite.utas.edu.au/5430 Medical and Health Sciences Immunology Cellular Immunology Refereed Article PeerReviewed 1995 ftunivtasecite https://doi.org/10.1038/icb.1995.48 2019-12-13T20:52:50Z Cell-mediated immune responses were studied in 12 Antarctic and sub-Antarctic wintering groups at quarterly intervals over the period 1984-1992, using the cutaneous CMI Multitest. These populations are among the most isolated on earth. While the sub-Antarctic population at Macquarie Island had levels of responsiveness and hypoergy (9%) comparable to healthy populations in temperate zones, the Antarctic Continental group showed a level of hypoergy of 36%. There was no seasonal variation in the pattern of responses. It is concluded that the extreme and isolated environment and stress factors are responsible for the decreased immunological responsiveness but the mechanisms are presently unclear. On review, one factor appears to be perceived anxiety. The high rate of hypoergy in Antarctica, where medical care is limited, may have health implications. These groups provide an excellent analogue for immunological investigations in longer term space flight. Article in Journal/Newspaper Antarc* Antarctic Antarctica Macquarie Island eCite UTAS (University of Tasmania) Antarctic The Antarctic Immunology and Cell Biology 73 4 316 320 |
institution |
Open Polar |
collection |
eCite UTAS (University of Tasmania) |
op_collection_id |
ftunivtasecite |
language |
English |
topic |
Medical and Health Sciences Immunology Cellular Immunology |
spellingShingle |
Medical and Health Sciences Immunology Cellular Immunology Muller, HK Lugg, DJ Quinn, D Cell mediated immunity in Antarctic wintering personnel; 1984-1992 |
topic_facet |
Medical and Health Sciences Immunology Cellular Immunology |
description |
Cell-mediated immune responses were studied in 12 Antarctic and sub-Antarctic wintering groups at quarterly intervals over the period 1984-1992, using the cutaneous CMI Multitest. These populations are among the most isolated on earth. While the sub-Antarctic population at Macquarie Island had levels of responsiveness and hypoergy (9%) comparable to healthy populations in temperate zones, the Antarctic Continental group showed a level of hypoergy of 36%. There was no seasonal variation in the pattern of responses. It is concluded that the extreme and isolated environment and stress factors are responsible for the decreased immunological responsiveness but the mechanisms are presently unclear. On review, one factor appears to be perceived anxiety. The high rate of hypoergy in Antarctica, where medical care is limited, may have health implications. These groups provide an excellent analogue for immunological investigations in longer term space flight. |
format |
Article in Journal/Newspaper |
author |
Muller, HK Lugg, DJ Quinn, D |
author_facet |
Muller, HK Lugg, DJ Quinn, D |
author_sort |
Muller, HK |
title |
Cell mediated immunity in Antarctic wintering personnel; 1984-1992 |
title_short |
Cell mediated immunity in Antarctic wintering personnel; 1984-1992 |
title_full |
Cell mediated immunity in Antarctic wintering personnel; 1984-1992 |
title_fullStr |
Cell mediated immunity in Antarctic wintering personnel; 1984-1992 |
title_full_unstemmed |
Cell mediated immunity in Antarctic wintering personnel; 1984-1992 |
title_sort |
cell mediated immunity in antarctic wintering personnel; 1984-1992 |
publisher |
Blackwell Publishing Asia |
publishDate |
1995 |
url |
https://doi.org/10.1038/icb.1995.48 http://www.ncbi.nlm.nih.gov/pubmed/7493767 http://ecite.utas.edu.au/5430 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic Antarctica Macquarie Island |
genre_facet |
Antarc* Antarctic Antarctica Macquarie Island |
op_relation |
http://dx.doi.org/10.1038/icb.1995.48 Muller, HK and Lugg, DJ and Quinn, D, Cell mediated immunity in Antarctic wintering personnel; 1984-1992, Immunology and Cell Biology, 73, (4) pp. 316-320. ISSN 0818-9641 (1995) [Refereed Article] http://www.ncbi.nlm.nih.gov/pubmed/7493767 http://ecite.utas.edu.au/5430 |
op_doi |
https://doi.org/10.1038/icb.1995.48 |
container_title |
Immunology and Cell Biology |
container_volume |
73 |
container_issue |
4 |
container_start_page |
316 |
op_container_end_page |
320 |
_version_ |
1766264204077039616 |