Immune responses during an antarctic summer
The immune status of 29 members of the Australian National Antarctic Research Expeditions (ANARE) was investigated before, during, and after a 56 day summer voyage to Antarctica and correlated with psychological and physiological parameters. All subjects were healthy. Expedition personnel demonstrat...
Published in: | Pathology |
---|---|
Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Carfax Publishing
1995
|
Subjects: | |
Online Access: | https://doi.org/10.1080/00313029500169852 http://www.ncbi.nlm.nih.gov/pubmed/7567151 http://ecite.utas.edu.au/5428 |
id |
ftunivtasecite:oai:ecite.utas.edu.au:5428 |
---|---|
record_format |
openpolar |
spelling |
ftunivtasecite:oai:ecite.utas.edu.au:5428 2023-05-15T13:56:40+02:00 Immune responses during an antarctic summer Muller, HK Lugg, DJ Ursin, H Quinn, D Donovan, K 1995 https://doi.org/10.1080/00313029500169852 http://www.ncbi.nlm.nih.gov/pubmed/7567151 http://ecite.utas.edu.au/5428 en eng Carfax Publishing http://dx.doi.org/10.1080/00313029500169852 Muller, HK and Lugg, DJ and Ursin, H and Quinn, D and Donovan, K, Immune responses during an antarctic summer, Pathology, 27, (2) pp. 186-190. ISSN 0031-3025 (1995) [Refereed Article] http://www.ncbi.nlm.nih.gov/pubmed/7567151 http://ecite.utas.edu.au/5428 Medical and Health Sciences Immunology Cellular Immunology Refereed Article PeerReviewed 1995 ftunivtasecite https://doi.org/10.1080/00313029500169852 2019-12-13T20:52:50Z The immune status of 29 members of the Australian National Antarctic Research Expeditions (ANARE) was investigated before, during, and after a 56 day summer voyage to Antarctica and correlated with psychological and physiological parameters. All subjects were healthy. Expedition personnel demonstrated decreased cell mediated immune responses (CMI) assessed by the CMI Multi-test; 21% were hypoergic. The major associated observation was a significant negative correlation with anxiety in Antarctica. However, perceived anxiety was greater before and after the voyage. No significant changes were found in T and B lymphocyte subsets, immunoglobulin and complement components and cutaneous blood flow, nor was there any clinical evidence of illness. Of the hormones examined only cortisol was low predeparture which may reflect increased perceived anxiety at that time. Changes in immune control mechanism were apparent as shown by reduced CMI responses and lowered tetanus antibody levels. Stress factors are postulated to induce depression of the immune response in Antarctica. The association with anxiety suggests that brain peptides or associated cytokines may have a role in mediating these immune events. Such alterations in immune status have implications for health management in isolated and extreme conditions. Article in Journal/Newspaper Antarc* Antarctic Antarctica eCite UTAS (University of Tasmania) Antarctic Pathology 27 2 186 190 |
institution |
Open Polar |
collection |
eCite UTAS (University of Tasmania) |
op_collection_id |
ftunivtasecite |
language |
English |
topic |
Medical and Health Sciences Immunology Cellular Immunology |
spellingShingle |
Medical and Health Sciences Immunology Cellular Immunology Muller, HK Lugg, DJ Ursin, H Quinn, D Donovan, K Immune responses during an antarctic summer |
topic_facet |
Medical and Health Sciences Immunology Cellular Immunology |
description |
The immune status of 29 members of the Australian National Antarctic Research Expeditions (ANARE) was investigated before, during, and after a 56 day summer voyage to Antarctica and correlated with psychological and physiological parameters. All subjects were healthy. Expedition personnel demonstrated decreased cell mediated immune responses (CMI) assessed by the CMI Multi-test; 21% were hypoergic. The major associated observation was a significant negative correlation with anxiety in Antarctica. However, perceived anxiety was greater before and after the voyage. No significant changes were found in T and B lymphocyte subsets, immunoglobulin and complement components and cutaneous blood flow, nor was there any clinical evidence of illness. Of the hormones examined only cortisol was low predeparture which may reflect increased perceived anxiety at that time. Changes in immune control mechanism were apparent as shown by reduced CMI responses and lowered tetanus antibody levels. Stress factors are postulated to induce depression of the immune response in Antarctica. The association with anxiety suggests that brain peptides or associated cytokines may have a role in mediating these immune events. Such alterations in immune status have implications for health management in isolated and extreme conditions. |
format |
Article in Journal/Newspaper |
author |
Muller, HK Lugg, DJ Ursin, H Quinn, D Donovan, K |
author_facet |
Muller, HK Lugg, DJ Ursin, H Quinn, D Donovan, K |
author_sort |
Muller, HK |
title |
Immune responses during an antarctic summer |
title_short |
Immune responses during an antarctic summer |
title_full |
Immune responses during an antarctic summer |
title_fullStr |
Immune responses during an antarctic summer |
title_full_unstemmed |
Immune responses during an antarctic summer |
title_sort |
immune responses during an antarctic summer |
publisher |
Carfax Publishing |
publishDate |
1995 |
url |
https://doi.org/10.1080/00313029500169852 http://www.ncbi.nlm.nih.gov/pubmed/7567151 http://ecite.utas.edu.au/5428 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Antarctica |
genre_facet |
Antarc* Antarctic Antarctica |
op_relation |
http://dx.doi.org/10.1080/00313029500169852 Muller, HK and Lugg, DJ and Ursin, H and Quinn, D and Donovan, K, Immune responses during an antarctic summer, Pathology, 27, (2) pp. 186-190. ISSN 0031-3025 (1995) [Refereed Article] http://www.ncbi.nlm.nih.gov/pubmed/7567151 http://ecite.utas.edu.au/5428 |
op_doi |
https://doi.org/10.1080/00313029500169852 |
container_title |
Pathology |
container_volume |
27 |
container_issue |
2 |
container_start_page |
186 |
op_container_end_page |
190 |
_version_ |
1766264203915558912 |