The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.)
Atlantic salmon (Salmo salar L.) were administered a levamisole-adjuvanted or non-adjuvanted Vibrio anguillarum vaccine by either bath or intraperitoneal (IP) injection. The potential side effects of vaccination were investigated at a histological level, with the skin, gills, anterior kidney and spl...
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2001
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ftunivtasecite:oai:ecite.utas.edu.au:21085 2023-05-15T15:31:10+02:00 The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) Morrison, RN Nowak, BF Carson, J 2001 https://doi.org/10.1016/S0044-8486(00)00546-9 http://ecite.utas.edu.au/21085 en eng Elsevier Science http://dx.doi.org/10.1016/S0044-8486(00)00546-9 Morrison, RN and Nowak, BF and Carson, J, The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.), Aquaculture , 195, (1) pp. 23-33. ISSN 0044-8486 (2001) [Refereed Article] http://ecite.utas.edu.au/21085 Agricultural and Veterinary Sciences Fisheries Sciences Fish Pests and Diseases Refereed Article PeerReviewed 2001 ftunivtasecite https://doi.org/10.1016/S0044-8486(00)00546-9 2019-12-13T21:03:19Z Atlantic salmon (Salmo salar L.) were administered a levamisole-adjuvanted or non-adjuvanted Vibrio anguillarum vaccine by either bath or intraperitoneal (IP) injection. The potential side effects of vaccination were investigated at a histological level, with the skin, gills, anterior kidney and spleen all examined. At a gross level, no pathological changes were evident in any organs. Observations of histological structures found that the skin, anterior kidney and spleen were not affected by vaccination. However pathological changes were observed in the gills of fish treated with the adjuvanted vaccine by both routes of administration. Pathology of the gills was multifocal and included hyperplasia of mucous cells, lamellar oedema, proliferation of chloride cells, inflammation and necrosis. Hyperplasia and hypertrophy of epithelial cells resulted in lamellar fusion. The abundance of lamellar associated mucous cells significantly increased in the gills of fish from groups administered the levanmisole-adjuvanted vaccine (IP and bath) (P < 0.05). However, the effect of the treatments on lamellar fusion was not significant (P > 0.05). 2001 Elsevier Science B.V. Article in Journal/Newspaper Atlantic salmon Salmo salar eCite UTAS (University of Tasmania) Aquaculture 195 1-2 23 33 |
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eCite UTAS (University of Tasmania) |
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ftunivtasecite |
language |
English |
topic |
Agricultural and Veterinary Sciences Fisheries Sciences Fish Pests and Diseases |
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Agricultural and Veterinary Sciences Fisheries Sciences Fish Pests and Diseases Morrison, RN Nowak, BF Carson, J The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) |
topic_facet |
Agricultural and Veterinary Sciences Fisheries Sciences Fish Pests and Diseases |
description |
Atlantic salmon (Salmo salar L.) were administered a levamisole-adjuvanted or non-adjuvanted Vibrio anguillarum vaccine by either bath or intraperitoneal (IP) injection. The potential side effects of vaccination were investigated at a histological level, with the skin, gills, anterior kidney and spleen all examined. At a gross level, no pathological changes were evident in any organs. Observations of histological structures found that the skin, anterior kidney and spleen were not affected by vaccination. However pathological changes were observed in the gills of fish treated with the adjuvanted vaccine by both routes of administration. Pathology of the gills was multifocal and included hyperplasia of mucous cells, lamellar oedema, proliferation of chloride cells, inflammation and necrosis. Hyperplasia and hypertrophy of epithelial cells resulted in lamellar fusion. The abundance of lamellar associated mucous cells significantly increased in the gills of fish from groups administered the levanmisole-adjuvanted vaccine (IP and bath) (P < 0.05). However, the effect of the treatments on lamellar fusion was not significant (P > 0.05). 2001 Elsevier Science B.V. |
format |
Article in Journal/Newspaper |
author |
Morrison, RN Nowak, BF Carson, J |
author_facet |
Morrison, RN Nowak, BF Carson, J |
author_sort |
Morrison, RN |
title |
The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) |
title_short |
The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) |
title_full |
The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) |
title_fullStr |
The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) |
title_full_unstemmed |
The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.) |
title_sort |
histopathological effects of a levamisole-adjuvanted vibrio anguillarum vaccine on atlantic salmon ( salmo salar l.) |
publisher |
Elsevier Science |
publishDate |
2001 |
url |
https://doi.org/10.1016/S0044-8486(00)00546-9 http://ecite.utas.edu.au/21085 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
http://dx.doi.org/10.1016/S0044-8486(00)00546-9 Morrison, RN and Nowak, BF and Carson, J, The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon ( Salmo salar L.), Aquaculture , 195, (1) pp. 23-33. ISSN 0044-8486 (2001) [Refereed Article] http://ecite.utas.edu.au/21085 |
op_doi |
https://doi.org/10.1016/S0044-8486(00)00546-9 |
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Aquaculture |
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195 |
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1-2 |
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23 |
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33 |
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1766361651498450944 |