Evaluation of levamisole as a treatment for amoebic gill disease of Atlantic salmon, Salmo salar L

• Published in: Journal of Fish Diseases
• Main Authors: Findlay, VL, Zilberg, D, Munday, BL
• Format: Article in Journal/Newspaper
• Language: English
• Published: Blackwell Science Ltd 2000
• Subjects: Agricultural and Veterinary Sciences; Fisheries Sciences; Fish Pests and Diseases; Atlantic salmon; Salmo salar
• Online Access: https://doi.org/10.1046/j.1365-2761.2000.00238.x; http://ecite.utas.edu.au/19014

Levamisole, a known T-cell stimulator and immunomodulator in mammals, has been demonstrated to enhance resistance to amoebic gill disease in Atlantic salmon, Salmo salar L. When used in fresh water baths, dose rates of 1.25, 2.5 and 5 ppm levamisole stimulated resistance to reinfection with Paramoeba sp. that was evident from 2-3 weeks post-treatment. It is proposed that this response is related to enhancement of the non-specific immune system.