No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s
Disclaimer: Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy, or views of the International Age...
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Online Access: | https://trepo.tuni.fi/handle/10024/151318 https://doi.org/10.3390/cancers15164079 |
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ftunivtampere:oai:trepo.tuni.fi:10024/151318 2024-01-07T09:44:11+01:00 No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s Laakso, Laura Jokelainen, Pikka Houe, Hans Skjerve, Eystein Hansen, Johnni Lynge, Elsebeth Martinsen, Jan-Ivar Mehlum, Ingrid Sivesind Selander, Jenny Torfadóttir, Jóhanna Eyrún Weiderpass, Elisabete Heikkinen, Sanna Pukkala, Eero Tampere University Health Sciences 2023-08 7 236561 fulltext https://trepo.tuni.fi/handle/10024/151318 https://doi.org/10.3390/cancers15164079 en eng 4079 16 15 2072-6694 https://trepo.tuni.fi/handle/10024/151318 URN:NBN:fi:tuni-202309198295 doi:10.3390/cancers15164079 cc by 4.0 openAccess 3142 Public health care science environmental and occupational health 3122 Cancers article 2023 ftunivtampere https://doi.org/10.3390/cancers15164079 2023-12-14T00:09:28Z Disclaimer: Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization. The cancer profile of veterinarians has received little research attention, despite the profession potentially being exposed to a wide range of known and suspected carcinogens. In this large-scale cohort study, we assessed cancer incidence in veterinarians in Denmark, Finland, Iceland, Norway, and Sweden, across more than 40 years (1961–2005). The cohort comprised 4708 veterinarians and 119,503 person-years at follow-up. The overall cancer incidence in veterinarians was close to the incidence in the total population in all countries and in all age groups. In male veterinarians, the standardized incidence ratios (SIR) in 1961–1990 were elevated for colon cancer (1.86, 95% confidence interval (CI) 1.39–2.44), prostate cancer (1.35, 95% CI 1.07–1.67), and especially skin melanoma (3.62, 95% CI 2.78–2.84), while there was no longer any statistically significant excess in the more recent follow-up period. Decreased SIRs were observed for lip cancer (0.11, 95% CI 0.00–0.62), laryngeal cancer (0.38, 95% CI 0.12–0.89), lung cancer (0.59, 95% CI 0.47–0.74), and stomach cancer (0.58, 95% CI 0.38–0.86), without a marked change in SIR over time. Non-significant excesses among male veterinarians were also observed in Hodgkin lymphoma (1961–1990 only), and leukaemia. This multi-country study indicates that there was an elevated incidence of several cancer types among male veterinarians before the 1990s but not after that. Some of the findings might rather be attributed to lifestyle factors and not directly to work conditions, but the excess risk of cancers of kidney and bladder, for example, might be related to work exposures. Peer reviewed Article in Journal/Newspaper Iceland Tampere University: Trepo Norway Cancers 15 16 4079 |
institution |
Open Polar |
collection |
Tampere University: Trepo |
op_collection_id |
ftunivtampere |
language |
English |
topic |
3142 Public health care science environmental and occupational health 3122 Cancers |
spellingShingle |
3142 Public health care science environmental and occupational health 3122 Cancers Laakso, Laura Jokelainen, Pikka Houe, Hans Skjerve, Eystein Hansen, Johnni Lynge, Elsebeth Martinsen, Jan-Ivar Mehlum, Ingrid Sivesind Selander, Jenny Torfadóttir, Jóhanna Eyrún Weiderpass, Elisabete Heikkinen, Sanna Pukkala, Eero No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s |
topic_facet |
3142 Public health care science environmental and occupational health 3122 Cancers |
description |
Disclaimer: Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization. The cancer profile of veterinarians has received little research attention, despite the profession potentially being exposed to a wide range of known and suspected carcinogens. In this large-scale cohort study, we assessed cancer incidence in veterinarians in Denmark, Finland, Iceland, Norway, and Sweden, across more than 40 years (1961–2005). The cohort comprised 4708 veterinarians and 119,503 person-years at follow-up. The overall cancer incidence in veterinarians was close to the incidence in the total population in all countries and in all age groups. In male veterinarians, the standardized incidence ratios (SIR) in 1961–1990 were elevated for colon cancer (1.86, 95% confidence interval (CI) 1.39–2.44), prostate cancer (1.35, 95% CI 1.07–1.67), and especially skin melanoma (3.62, 95% CI 2.78–2.84), while there was no longer any statistically significant excess in the more recent follow-up period. Decreased SIRs were observed for lip cancer (0.11, 95% CI 0.00–0.62), laryngeal cancer (0.38, 95% CI 0.12–0.89), lung cancer (0.59, 95% CI 0.47–0.74), and stomach cancer (0.58, 95% CI 0.38–0.86), without a marked change in SIR over time. Non-significant excesses among male veterinarians were also observed in Hodgkin lymphoma (1961–1990 only), and leukaemia. This multi-country study indicates that there was an elevated incidence of several cancer types among male veterinarians before the 1990s but not after that. Some of the findings might rather be attributed to lifestyle factors and not directly to work conditions, but the excess risk of cancers of kidney and bladder, for example, might be related to work exposures. Peer reviewed |
author2 |
Tampere University Health Sciences |
format |
Article in Journal/Newspaper |
author |
Laakso, Laura Jokelainen, Pikka Houe, Hans Skjerve, Eystein Hansen, Johnni Lynge, Elsebeth Martinsen, Jan-Ivar Mehlum, Ingrid Sivesind Selander, Jenny Torfadóttir, Jóhanna Eyrún Weiderpass, Elisabete Heikkinen, Sanna Pukkala, Eero |
author_facet |
Laakso, Laura Jokelainen, Pikka Houe, Hans Skjerve, Eystein Hansen, Johnni Lynge, Elsebeth Martinsen, Jan-Ivar Mehlum, Ingrid Sivesind Selander, Jenny Torfadóttir, Jóhanna Eyrún Weiderpass, Elisabete Heikkinen, Sanna Pukkala, Eero |
author_sort |
Laakso, Laura |
title |
No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s |
title_short |
No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s |
title_full |
No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s |
title_fullStr |
No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s |
title_full_unstemmed |
No Excess Cancer Risk among Veterinarians in Denmark, Finland, Iceland, Norway, and Sweden after the 1980s |
title_sort |
no excess cancer risk among veterinarians in denmark, finland, iceland, norway, and sweden after the 1980s |
publishDate |
2023 |
url |
https://trepo.tuni.fi/handle/10024/151318 https://doi.org/10.3390/cancers15164079 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
4079 16 15 2072-6694 https://trepo.tuni.fi/handle/10024/151318 URN:NBN:fi:tuni-202309198295 doi:10.3390/cancers15164079 |
op_rights |
cc by 4.0 openAccess |
op_doi |
https://doi.org/10.3390/cancers15164079 |
container_title |
Cancers |
container_volume |
15 |
container_issue |
16 |
container_start_page |
4079 |
_version_ |
1787425523787366400 |