Genetics and genomics of myxomatous mitral valve disease in dogs

• Main Author: O'Brien, Mitchell John
• Format: Thesis
• Language: English
• Published: The University of Sydney 2022
• Subjects: genetics; genomics; canine; dog; complex trait; disease; Cavalier; Canis lupus
• Online Access: https://hdl.handle.net/2123/27483

As a result of its unique evolutionary history, the modern dog (Canis lupus familiaris) has a simplified genetic landscape that makes it a strong model for investigating the genetic basis of breed specific traits and diseases. This thesis applies genomic methodologies to a complex disease, myxomatou...