DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP-2*) in Atlantic salmon (Salmo salar L.)

A non-synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP-dependent mMEP-2* locus in Atlantic salmon (\textit{Salmo salar} L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differ...

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Bibliographic Details
Published in:Journal of Fish Biology
Main Authors: Taggart, John B, Leaver, Michael J, Bekaert, Michaël
Other Authors: Institute of Aquaculture, orcid:0000-0002-3843-9663, orcid:0000-0002-3155-0844, orcid:0000-0002-1206-7654
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 2022
Subjects:
SNP
Online Access:http://hdl.handle.net/1893/34564
https://doi.org/10.1111/jfb.15182
http://dspace.stir.ac.uk/retrieve/570ed03a-dd10-47f1-b071-add0e176cd53/Journal%20of%20Fish%20Biology%20-%202022%20-%20Taggart%20-%20DNA%20polymorphism%20underlying%20allozyme%20variation%20at%20a%20malic%20enzyme%20locus%20mMEP___2%20.pdf
Description
Summary:A non-synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP-dependent mMEP-2* locus in Atlantic salmon (\textit{Salmo salar} L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mobility of the two allozyme alleles, while allozyme and SNP assays revealed genotyping concordance in 257 of 258 individuals. A single mismatch, homozygous allozyme vs heterozygote SNP, suggests the presence of a second, less common null allele. Output Status: Forthcoming/Available Online