Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array
We examined five families from the Mainstream Canada Atlantic salmon broodstock program to identify quantitative trait loci (QTL) associated with body-weight at four time points during a commercial production cycle. The parents and 49–65 progeny from each family were genotyped using a 6.5 K single n...
Published in: | Aquaculture |
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Language: | English |
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Online Access: | http://hdl.handle.net/1893/33309 https://doi.org/10.1016/j.aquaculture.2012.06.017 http://dspace.stir.ac.uk/retrieve/47112bc1-af57-4075-b3f1-0e26a603ef4d/1-s2.0-S0044848612003705-main.pdf |
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ftunivstirling:oai:dspace.stir.ac.uk:1893/33309 2023-05-15T15:29:45+02:00 Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array Gutierrez, Alejandro P Lubieniecki, Krzysztof P Davidson, Evelyn A Lien, Sigbjørn Kent, Matthew P Fukui, Steve Withler, Ruth E Swift, Bruce Davidson, William S Simon Fraser University Norwegian University of Life Sciences Mainstream Canada Fisheries and Oceans Canada TRI-GEN Fish Improvement Ltd 2012-08 application/pdf http://hdl.handle.net/1893/33309 https://doi.org/10.1016/j.aquaculture.2012.06.017 http://dspace.stir.ac.uk/retrieve/47112bc1-af57-4075-b3f1-0e26a603ef4d/1-s2.0-S0044848612003705-main.pdf en eng Elsevier BV Gutierrez AP, Lubieniecki KP, Davidson EA, Lien S, Kent MP, Fukui S, Withler RE, Swift B & Davidson WS (2012) Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array. Aquaculture, 358-359, pp. 61-70. https://doi.org/10.1016/j.aquaculture.2012.06.017 http://hdl.handle.net/1893/33309 doi:10.1016/j.aquaculture.2012.06.017 WOS:000307292700008 2-s2.0-84863832635 1684986 http://dspace.stir.ac.uk/retrieve/47112bc1-af57-4075-b3f1-0e26a603ef4d/1-s2.0-S0044848612003705-main.pdf The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. http://www.rioxx.net/licenses/under-embargo-all-rights-reserved 2999-12-31 [1-s2.0-S0044848612003705-main.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work. Atlantic salmon Quantitative trait loci Body-weight Breeding program Journal Article VoR - Version of Record 2012 ftunivstirling https://doi.org/10.1016/j.aquaculture.2012.06.017 2022-06-13T18:44:41Z We examined five families from the Mainstream Canada Atlantic salmon broodstock program to identify quantitative trait loci (QTL) associated with body-weight at four time points during a commercial production cycle. The parents and 49–65 progeny from each family were genotyped using a 6.5 K single nucleotide polymorphism (SNP) array. Uninformative markers were removed from each family dataset, and approximately 2500 informative markers per family were positioned on male and female linkage maps, which had been constructed using the same SNP array. QTL analysis was carried out using GridQTL software utilizing the Sib-Pair model to take advantage of the full-sib nature of the families. We also did half-sib analyses to identify segregating alleles from dams or sires with a QTL. Significance thresholds to assess QTL effects were obtained from a 10,000 permutation test. We identified genome-wide significant QTL (P < 0.05) linked to chromosomes Ssa02, Ssa07, Ssa13, Ssa09, Ssa17 and Ssa26, and also several chromosomes which contain significant (P < 0.01) and suggestive QTL (P < 0.05) associated with body-weight. Some of these QTL have previously been identified as being associated with body-weight in Atlantic salmon. Our findings provide useful evidence of QTL associated with body-weight traits. These QTL should be valuable candidates for use in the Mainstream Canada marker-assisted selection breeding program. Moreover, it is an important step towards the identification of genes and the understanding of the genetic components underlying growth and body-weight in Atlantic salmon. Article in Journal/Newspaper Atlantic salmon Salmo salar University of Stirling: Stirling Digital Research Repository Canada Aquaculture 358-359 61 70 |
institution |
Open Polar |
collection |
University of Stirling: Stirling Digital Research Repository |
op_collection_id |
ftunivstirling |
language |
English |
topic |
Atlantic salmon Quantitative trait loci Body-weight Breeding program |
spellingShingle |
Atlantic salmon Quantitative trait loci Body-weight Breeding program Gutierrez, Alejandro P Lubieniecki, Krzysztof P Davidson, Evelyn A Lien, Sigbjørn Kent, Matthew P Fukui, Steve Withler, Ruth E Swift, Bruce Davidson, William S Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array |
topic_facet |
Atlantic salmon Quantitative trait loci Body-weight Breeding program |
description |
We examined five families from the Mainstream Canada Atlantic salmon broodstock program to identify quantitative trait loci (QTL) associated with body-weight at four time points during a commercial production cycle. The parents and 49–65 progeny from each family were genotyped using a 6.5 K single nucleotide polymorphism (SNP) array. Uninformative markers were removed from each family dataset, and approximately 2500 informative markers per family were positioned on male and female linkage maps, which had been constructed using the same SNP array. QTL analysis was carried out using GridQTL software utilizing the Sib-Pair model to take advantage of the full-sib nature of the families. We also did half-sib analyses to identify segregating alleles from dams or sires with a QTL. Significance thresholds to assess QTL effects were obtained from a 10,000 permutation test. We identified genome-wide significant QTL (P < 0.05) linked to chromosomes Ssa02, Ssa07, Ssa13, Ssa09, Ssa17 and Ssa26, and also several chromosomes which contain significant (P < 0.01) and suggestive QTL (P < 0.05) associated with body-weight. Some of these QTL have previously been identified as being associated with body-weight in Atlantic salmon. Our findings provide useful evidence of QTL associated with body-weight traits. These QTL should be valuable candidates for use in the Mainstream Canada marker-assisted selection breeding program. Moreover, it is an important step towards the identification of genes and the understanding of the genetic components underlying growth and body-weight in Atlantic salmon. |
author2 |
Simon Fraser University Norwegian University of Life Sciences Mainstream Canada Fisheries and Oceans Canada TRI-GEN Fish Improvement Ltd |
format |
Article in Journal/Newspaper |
author |
Gutierrez, Alejandro P Lubieniecki, Krzysztof P Davidson, Evelyn A Lien, Sigbjørn Kent, Matthew P Fukui, Steve Withler, Ruth E Swift, Bruce Davidson, William S |
author_facet |
Gutierrez, Alejandro P Lubieniecki, Krzysztof P Davidson, Evelyn A Lien, Sigbjørn Kent, Matthew P Fukui, Steve Withler, Ruth E Swift, Bruce Davidson, William S |
author_sort |
Gutierrez, Alejandro P |
title |
Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array |
title_short |
Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array |
title_full |
Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array |
title_fullStr |
Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array |
title_full_unstemmed |
Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array |
title_sort |
genetic mapping of quantitative trait loci (qtl) for body-weight in atlantic salmon (salmo salar) using a 6.5k snp array |
publisher |
Elsevier BV |
publishDate |
2012 |
url |
http://hdl.handle.net/1893/33309 https://doi.org/10.1016/j.aquaculture.2012.06.017 http://dspace.stir.ac.uk/retrieve/47112bc1-af57-4075-b3f1-0e26a603ef4d/1-s2.0-S0044848612003705-main.pdf |
geographic |
Canada |
geographic_facet |
Canada |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
Gutierrez AP, Lubieniecki KP, Davidson EA, Lien S, Kent MP, Fukui S, Withler RE, Swift B & Davidson WS (2012) Genetic mapping of quantitative trait loci (QTL) for body-weight in Atlantic salmon (Salmo salar) using a 6.5K SNP array. Aquaculture, 358-359, pp. 61-70. https://doi.org/10.1016/j.aquaculture.2012.06.017 http://hdl.handle.net/1893/33309 doi:10.1016/j.aquaculture.2012.06.017 WOS:000307292700008 2-s2.0-84863832635 1684986 http://dspace.stir.ac.uk/retrieve/47112bc1-af57-4075-b3f1-0e26a603ef4d/1-s2.0-S0044848612003705-main.pdf |
op_rights |
The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. http://www.rioxx.net/licenses/under-embargo-all-rights-reserved 2999-12-31 [1-s2.0-S0044848612003705-main.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work. |
op_doi |
https://doi.org/10.1016/j.aquaculture.2012.06.017 |
container_title |
Aquaculture |
container_volume |
358-359 |
container_start_page |
61 |
op_container_end_page |
70 |
_version_ |
1766360184274288640 |