A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions
Background: Atlantic salmon have been subject to domestication for approximately ten generations, beginning in the early 1970s. This process of artificial selection will have created various genetic differences between wild and farmed stocks. Each year, hundreds of thousands of farmed fish escape in...
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Online Access: | http://hdl.handle.net/1893/21222 https://doi.org/10.1186/1471-2164-15-884 http://dspace.stir.ac.uk/bitstream/1893/21222/1/BMC%20Genomics%202014.pdf |
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ftunivstirling:oai:dspace.stir.ac.uk:1893/21222 2023-05-15T15:30:41+02:00 A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions Berdal, Beatrix Bron, James Glover, Kevin A Taggart, John University of Stirling Institute of Aquaculture Norwegian Institute of Marine Research orcid:0000-0003-3544-0519 orcid:0000-0002-3843-9663 2014-10-09 application/pdf http://hdl.handle.net/1893/21222 https://doi.org/10.1186/1471-2164-15-884 http://dspace.stir.ac.uk/bitstream/1893/21222/1/BMC%20Genomics%202014.pdf en eng BioMed Central Berdal B, Bron J, Glover KA & Taggart J (2014) A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions. BMC Genomics, 15, Art. No.: 884. https://doi.org/10.1186/1471-2164-15-884 884 http://hdl.handle.net/1893/21222 doi:10.1186/1471-2164-15-884 25301270 WOS:000344565000001 2-s2.0-84988843895 614250 http://dspace.stir.ac.uk/bitstream/1893/21222/1/BMC%20Genomics%202014.pdf © 2014 Bicskei et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. http://creativecommons.org/licenses/by/4.0/ CC0 PDM CC-BY Domestication selection Microarray Atlantic salmon Gene expression Farm escapees Maternal effects Journal Article VoR - Version of Record 2014 ftunivstirling https://doi.org/10.1186/1471-2164-15-884 2022-06-13T18:45:19Z Background: Atlantic salmon have been subject to domestication for approximately ten generations, beginning in the early 1970s. This process of artificial selection will have created various genetic differences between wild and farmed stocks. Each year, hundreds of thousands of farmed fish escape into the wild. These escapees may interbreed with wild conspecifics raising concerns for both the fish-farming industry and fisheries managers. Thus, a better understanding of the interactions between domesticated and wild salmon is essential to the continued sustainability of the aquaculture industry and to the maintenance of healthy wild stocks. Results: We compared the transcriptomes of a wild Norwegian Atlantic salmon population (Figgjo) and a Norwegian farmed strain (Mowi) at two life stages: yolk sac fry and post first-feeding fry. The analysis employed 44k oligo-microarrays to analyse gene expression of 36 farmed, wild and hybrid (farmed dam x wild sire) individuals reared under identical hatchery conditions. Although some of the transcriptional differences detected overlapped between sampling points, our results highlighted the importance of studying various life stages. Compared to the wild population, the Mowi strain displayed up-regulation in mRNA translation-related and down regulation in nervous and immune system -related pathways in the sac fry, whereas up-regulation of digestive and endocrine activities, carbohydrate, energy, amino acid and lipid metabolism and down-regulation of environmental information processing and immune system pathways were evident in the feeding fry. Differentially regulated pathways that were common among life stages generally belonged to environmental information processing and immune system functional groups. In addition, we found indications of strong maternal effects, reinforcing the importance of including reciprocal hybrids in the analysis. Conclusions: In agreement with previous studies we showed that domestication has caused changes in the transcriptome of wild Atlantic ... Article in Journal/Newspaper Atlantic salmon Salmo salar University of Stirling: Stirling Digital Research Repository BMC Genomics 15 1 884 |
institution |
Open Polar |
collection |
University of Stirling: Stirling Digital Research Repository |
op_collection_id |
ftunivstirling |
language |
English |
topic |
Domestication selection Microarray Atlantic salmon Gene expression Farm escapees Maternal effects |
spellingShingle |
Domestication selection Microarray Atlantic salmon Gene expression Farm escapees Maternal effects Berdal, Beatrix Bron, James Glover, Kevin A Taggart, John A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions |
topic_facet |
Domestication selection Microarray Atlantic salmon Gene expression Farm escapees Maternal effects |
description |
Background: Atlantic salmon have been subject to domestication for approximately ten generations, beginning in the early 1970s. This process of artificial selection will have created various genetic differences between wild and farmed stocks. Each year, hundreds of thousands of farmed fish escape into the wild. These escapees may interbreed with wild conspecifics raising concerns for both the fish-farming industry and fisheries managers. Thus, a better understanding of the interactions between domesticated and wild salmon is essential to the continued sustainability of the aquaculture industry and to the maintenance of healthy wild stocks. Results: We compared the transcriptomes of a wild Norwegian Atlantic salmon population (Figgjo) and a Norwegian farmed strain (Mowi) at two life stages: yolk sac fry and post first-feeding fry. The analysis employed 44k oligo-microarrays to analyse gene expression of 36 farmed, wild and hybrid (farmed dam x wild sire) individuals reared under identical hatchery conditions. Although some of the transcriptional differences detected overlapped between sampling points, our results highlighted the importance of studying various life stages. Compared to the wild population, the Mowi strain displayed up-regulation in mRNA translation-related and down regulation in nervous and immune system -related pathways in the sac fry, whereas up-regulation of digestive and endocrine activities, carbohydrate, energy, amino acid and lipid metabolism and down-regulation of environmental information processing and immune system pathways were evident in the feeding fry. Differentially regulated pathways that were common among life stages generally belonged to environmental information processing and immune system functional groups. In addition, we found indications of strong maternal effects, reinforcing the importance of including reciprocal hybrids in the analysis. Conclusions: In agreement with previous studies we showed that domestication has caused changes in the transcriptome of wild Atlantic ... |
author2 |
University of Stirling Institute of Aquaculture Norwegian Institute of Marine Research orcid:0000-0003-3544-0519 orcid:0000-0002-3843-9663 |
format |
Article in Journal/Newspaper |
author |
Berdal, Beatrix Bron, James Glover, Kevin A Taggart, John |
author_facet |
Berdal, Beatrix Bron, James Glover, Kevin A Taggart, John |
author_sort |
Berdal, Beatrix |
title |
A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions |
title_short |
A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions |
title_full |
A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions |
title_fullStr |
A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions |
title_full_unstemmed |
A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions |
title_sort |
comparison of gene transcription profiles of domesticated and wild atlantic salmon (salmo salar l.) at early life stages, reared under controlled conditions |
publisher |
BioMed Central |
publishDate |
2014 |
url |
http://hdl.handle.net/1893/21222 https://doi.org/10.1186/1471-2164-15-884 http://dspace.stir.ac.uk/bitstream/1893/21222/1/BMC%20Genomics%202014.pdf |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
Berdal B, Bron J, Glover KA & Taggart J (2014) A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions. BMC Genomics, 15, Art. No.: 884. https://doi.org/10.1186/1471-2164-15-884 884 http://hdl.handle.net/1893/21222 doi:10.1186/1471-2164-15-884 25301270 WOS:000344565000001 2-s2.0-84988843895 614250 http://dspace.stir.ac.uk/bitstream/1893/21222/1/BMC%20Genomics%202014.pdf |
op_rights |
© 2014 Bicskei et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. http://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC0 PDM CC-BY |
op_doi |
https://doi.org/10.1186/1471-2164-15-884 |
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BMC Genomics |
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15 |
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