Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification
Calcifying marine invertebrates with complex life cycles are particularly at risk to climate changes as they undergo an abrupt ontogenetic shift during larval metamorphosis. Although our understanding of the larval response to climate changes is rapidly advancing, the proteome plasticity involved in...
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ftunivsthongkong:oai:repository.ust.hk:1783.1-59807 2023-05-15T17:49:54+02:00 Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification Mukherjee, Joy Wong, Kelvin K.w. Chandramouli, Kondethimmanahalli H. Qian, Peiyuan Leung, Priscilla T.y. Wu, Rudolf Shiu Sun Thiyagarajan, Vengatesen 2013 http://repository.ust.hk/ir/Record/1783.1-59807 https://doi.org/10.1242/jeb.094516 http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0022-0949&rft.volume=216&rft.issue=24&rft.date=2013&rft.spage=4580&rft.aulast=Mukherjee&rft.aufirst=J.&rft.atitle=Proteomic+response+of+marine+invertebrate+larvae+to+ocean+acidification+and+hypoxia+during+metamorphosis+and+calcification&rft.title=Journal+of+experimental+biology http://www.scopus.com/record/display.url?eid=2-s2.0-84890604821&origin=inward http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000328059000015 English eng http://repository.ust.hk/ir/Record/1783.1-59807 Journal of Experimental Biology, v. 216, (24), December 2013, p. 4580-4589 0022-0949 https://doi.org/10.1242/jeb.094516 http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0022-0949&rft.volume=216&rft.issue=24&rft.date=2013&rft.spage=4580&rft.aulast=Mukherjee&rft.aufirst=J.&rft.atitle=Proteomic+response+of+marine+invertebrate+larvae+to+ocean+acidification+and+hypoxia+during+metamorphosis+and+calcification&rft.title=Journal+of+experimental+biology http://www.scopus.com/record/display.url?eid=2-s2.0-84890604821&origin=inward http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000328059000015 Environmental proteomics Hypoxia Larval metamorphosis Ocean acidification Article 2013 ftunivsthongkong https://doi.org/10.1242/jeb.094516 2022-01-21T01:04:14Z Calcifying marine invertebrates with complex life cycles are particularly at risk to climate changes as they undergo an abrupt ontogenetic shift during larval metamorphosis. Although our understanding of the larval response to climate changes is rapidly advancing, the proteome plasticity involved in a compensatory response to climate change is still unknown. In this study, we investigated the proteomic response of metamorphosing larvae of the tubeworm Hydroides elegans, challenged with two climate change stressors, ocean acidification (OA; pH 7.6) and hypoxia (HYP; 2.8 mg O2 l-1), and with both combined. Using a twodimensional gel electrophoresis (2-DE)-based approach coupled with mass spectrometry, we found that climate change stressors did not affect metamorphosis except under OA, but altered the larval proteome and phosphorylation status. Metabolism and various stress and calcification-related proteins were downregulated in response to OA. In OA and HYP combined, HYP restored the expression of the calcification-related proteins to the control levels. We speculate that mild HYP stress could compensate for the negative effects of OA. This study also discusses the potential functions of selected proteins that might play important roles in larval acclimation and adaption to climate change. © 2013. Published by The Company of Biologists Ltd. Article in Journal/Newspaper Ocean acidification The Hong Kong University of Science and Technology: HKUST Institutional Repository Journal of Experimental Biology 216 24 4580 4589 |
institution |
Open Polar |
collection |
The Hong Kong University of Science and Technology: HKUST Institutional Repository |
op_collection_id |
ftunivsthongkong |
language |
English |
topic |
Environmental proteomics Hypoxia Larval metamorphosis Ocean acidification |
spellingShingle |
Environmental proteomics Hypoxia Larval metamorphosis Ocean acidification Mukherjee, Joy Wong, Kelvin K.w. Chandramouli, Kondethimmanahalli H. Qian, Peiyuan Leung, Priscilla T.y. Wu, Rudolf Shiu Sun Thiyagarajan, Vengatesen Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification |
topic_facet |
Environmental proteomics Hypoxia Larval metamorphosis Ocean acidification |
description |
Calcifying marine invertebrates with complex life cycles are particularly at risk to climate changes as they undergo an abrupt ontogenetic shift during larval metamorphosis. Although our understanding of the larval response to climate changes is rapidly advancing, the proteome plasticity involved in a compensatory response to climate change is still unknown. In this study, we investigated the proteomic response of metamorphosing larvae of the tubeworm Hydroides elegans, challenged with two climate change stressors, ocean acidification (OA; pH 7.6) and hypoxia (HYP; 2.8 mg O2 l-1), and with both combined. Using a twodimensional gel electrophoresis (2-DE)-based approach coupled with mass spectrometry, we found that climate change stressors did not affect metamorphosis except under OA, but altered the larval proteome and phosphorylation status. Metabolism and various stress and calcification-related proteins were downregulated in response to OA. In OA and HYP combined, HYP restored the expression of the calcification-related proteins to the control levels. We speculate that mild HYP stress could compensate for the negative effects of OA. This study also discusses the potential functions of selected proteins that might play important roles in larval acclimation and adaption to climate change. © 2013. Published by The Company of Biologists Ltd. |
format |
Article in Journal/Newspaper |
author |
Mukherjee, Joy Wong, Kelvin K.w. Chandramouli, Kondethimmanahalli H. Qian, Peiyuan Leung, Priscilla T.y. Wu, Rudolf Shiu Sun Thiyagarajan, Vengatesen |
author_facet |
Mukherjee, Joy Wong, Kelvin K.w. Chandramouli, Kondethimmanahalli H. Qian, Peiyuan Leung, Priscilla T.y. Wu, Rudolf Shiu Sun Thiyagarajan, Vengatesen |
author_sort |
Mukherjee, Joy |
title |
Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification |
title_short |
Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification |
title_full |
Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification |
title_fullStr |
Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification |
title_full_unstemmed |
Proteomic Response of Marine Invertebrate Larvae to Ocean Acidification and Hypoxia During Metamorphosis and Calcification |
title_sort |
proteomic response of marine invertebrate larvae to ocean acidification and hypoxia during metamorphosis and calcification |
publishDate |
2013 |
url |
http://repository.ust.hk/ir/Record/1783.1-59807 https://doi.org/10.1242/jeb.094516 http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0022-0949&rft.volume=216&rft.issue=24&rft.date=2013&rft.spage=4580&rft.aulast=Mukherjee&rft.aufirst=J.&rft.atitle=Proteomic+response+of+marine+invertebrate+larvae+to+ocean+acidification+and+hypoxia+during+metamorphosis+and+calcification&rft.title=Journal+of+experimental+biology http://www.scopus.com/record/display.url?eid=2-s2.0-84890604821&origin=inward http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000328059000015 |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_relation |
http://repository.ust.hk/ir/Record/1783.1-59807 Journal of Experimental Biology, v. 216, (24), December 2013, p. 4580-4589 0022-0949 https://doi.org/10.1242/jeb.094516 http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0022-0949&rft.volume=216&rft.issue=24&rft.date=2013&rft.spage=4580&rft.aulast=Mukherjee&rft.aufirst=J.&rft.atitle=Proteomic+response+of+marine+invertebrate+larvae+to+ocean+acidification+and+hypoxia+during+metamorphosis+and+calcification&rft.title=Journal+of+experimental+biology http://www.scopus.com/record/display.url?eid=2-s2.0-84890604821&origin=inward http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000328059000015 |
op_doi |
https://doi.org/10.1242/jeb.094516 |
container_title |
Journal of Experimental Biology |
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216 |
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24 |
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4580 |
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4589 |
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