Endocrine Disruptors in Mediterranean Top Marine Predators
Background, Aims and Scope. Man-made Endocrine Disruptors (EDs) range across all continents and oceans. Some geographic areas are potentially more threatened than others: one of these is the Mediterranean Sea. Levels of some xenobiotics are much higher here than in other seas and oceans. In this pap...
Published in: | Environmental Science and Pollution Research - International |
---|---|
Main Authors: | , , |
Other Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Ecomed Verlagsgesellschaft AG:Justus von Liebig Str 1, D 86899 Landsberg Germany:011 49 8191 1250, EMAIL: a.heinrich@ecomed.de, INTERNET: http://www.ecomed.de, Fax: 011 49 8191 125594
2006
|
Subjects: | |
Online Access: | http://hdl.handle.net/11365/7749 https://doi.org/10.1065/espr2006.01.018 |
id |
ftunivsiena:oai:usiena-air.unisi.it:11365/7749 |
---|---|
record_format |
openpolar |
spelling |
ftunivsiena:oai:usiena-air.unisi.it:11365/7749 2024-02-11T10:02:20+01:00 Endocrine Disruptors in Mediterranean Top Marine Predators FOSSI, M. C. CASINI, S. MARSILI, L. Fossi, M. C. Casini, S. Marsili, L. 2006 STAMPA http://hdl.handle.net/11365/7749 https://doi.org/10.1065/espr2006.01.018 eng eng Ecomed Verlagsgesellschaft AG:Justus von Liebig Str 1, D 86899 Landsberg Germany:011 49 8191 1250, EMAIL: a.heinrich@ecomed.de, INTERNET: http://www.ecomed.de, Fax: 011 49 8191 125594 info:eu-repo/semantics/altIdentifier/pmid/16758711 info:eu-repo/semantics/altIdentifier/wos/WOS:000237554100010 volume:13 issue:3 firstpage:204 lastpage:207 numberofpages:4 journal:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH INTERNATIONAL http://hdl.handle.net/11365/7749 doi:10.1065/espr2006.01.018 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-33646836959 info:eu-repo/semantics/closedAccess endocrine disruptor fibroblast cell culture marine mammal Mediterranean sea skin biopsy top predator Vitellogenin Xiphias gladiu Zona Radiata proteins info:eu-repo/semantics/article 2006 ftunivsiena https://doi.org/10.1065/espr2006.01.018 2024-01-23T23:17:37Z Background, Aims and Scope. Man-made Endocrine Disruptors (EDs) range across all continents and oceans. Some geographic areas are potentially more threatened than others: one of these is the Mediterranean Sea. Levels of some xenobiotics are much higher here than in other seas and oceans. In this paper we review the final results of a project in which the hypothesis that Mediterranean top predator species (such as large pelagic fish and marine mammals) are potentially at risk due to EDs was investigated. Methods. In a four-year survey on the Mediterranean population of swordfish (Xiphias gladius), the potential toxicological effects of organochlorine compounds (OCs) on specimens of swordfish and tuna fish (Thunnus thynnus thynnus), caught in the spawning seasons from 1999 to 2002 in the Straits of Messina, Sicily (Italy), were investigated using vitellogenin (Vtg), Zona radiata proteins (Zrp), and cytochrome P4501A (CYP1A) activities (EROD, BPMO). Tissues (skin and blubber) were obtained from Stenella coeruleoalba, Tursiops truncatus, Delphinus delphis and Balaenoptera physalus from the western Ligurian Sea, between Corsica and the French-Italian coast, and Ionic Sea using biopsy darts launched with a crossbow. Benzo(α)pyrene monoxigenase (BPMO) activity was mesured in biopsies and cholrinated hydrocarbon levels were detected. Results and Discussion. We illustrate the need to develop and apply sensitive methodological tools, such as biomarkers (Vitellogenin, Zona Radiata proteins and CYP1A activities) for evaluation of toxicological risk in Xiphias gladius and Thunnus thynnus thynnus), and nondestructive biomarkers (CYP1A activities and fibroblast cell culture in skin biopsy), for the hazard assessment of threatened marine mammals species (Stenella coeruleoalba, Tursiops truncatus, Delphinus delphis and Balaenoptera physalus) exposed to EDs. Conclusion. The present research shows that: a) Vtg and Zrp can be used as diagnostic tools for fish stocks hazard assessment in the Mediterranean Sea; b) that CYP1A1 (BPMO) ... Article in Journal/Newspaper Balaenoptera physalus Università degli Studi di Siena: USiena air Environmental Science and Pollution Research - International 13 3 204 207 |
institution |
Open Polar |
collection |
Università degli Studi di Siena: USiena air |
op_collection_id |
ftunivsiena |
language |
English |
topic |
endocrine disruptor fibroblast cell culture marine mammal Mediterranean sea skin biopsy top predator Vitellogenin Xiphias gladiu Zona Radiata proteins |
spellingShingle |
endocrine disruptor fibroblast cell culture marine mammal Mediterranean sea skin biopsy top predator Vitellogenin Xiphias gladiu Zona Radiata proteins FOSSI, M. C. CASINI, S. MARSILI, L. Endocrine Disruptors in Mediterranean Top Marine Predators |
topic_facet |
endocrine disruptor fibroblast cell culture marine mammal Mediterranean sea skin biopsy top predator Vitellogenin Xiphias gladiu Zona Radiata proteins |
description |
Background, Aims and Scope. Man-made Endocrine Disruptors (EDs) range across all continents and oceans. Some geographic areas are potentially more threatened than others: one of these is the Mediterranean Sea. Levels of some xenobiotics are much higher here than in other seas and oceans. In this paper we review the final results of a project in which the hypothesis that Mediterranean top predator species (such as large pelagic fish and marine mammals) are potentially at risk due to EDs was investigated. Methods. In a four-year survey on the Mediterranean population of swordfish (Xiphias gladius), the potential toxicological effects of organochlorine compounds (OCs) on specimens of swordfish and tuna fish (Thunnus thynnus thynnus), caught in the spawning seasons from 1999 to 2002 in the Straits of Messina, Sicily (Italy), were investigated using vitellogenin (Vtg), Zona radiata proteins (Zrp), and cytochrome P4501A (CYP1A) activities (EROD, BPMO). Tissues (skin and blubber) were obtained from Stenella coeruleoalba, Tursiops truncatus, Delphinus delphis and Balaenoptera physalus from the western Ligurian Sea, between Corsica and the French-Italian coast, and Ionic Sea using biopsy darts launched with a crossbow. Benzo(α)pyrene monoxigenase (BPMO) activity was mesured in biopsies and cholrinated hydrocarbon levels were detected. Results and Discussion. We illustrate the need to develop and apply sensitive methodological tools, such as biomarkers (Vitellogenin, Zona Radiata proteins and CYP1A activities) for evaluation of toxicological risk in Xiphias gladius and Thunnus thynnus thynnus), and nondestructive biomarkers (CYP1A activities and fibroblast cell culture in skin biopsy), for the hazard assessment of threatened marine mammals species (Stenella coeruleoalba, Tursiops truncatus, Delphinus delphis and Balaenoptera physalus) exposed to EDs. Conclusion. The present research shows that: a) Vtg and Zrp can be used as diagnostic tools for fish stocks hazard assessment in the Mediterranean Sea; b) that CYP1A1 (BPMO) ... |
author2 |
Fossi, M. C. Casini, S. Marsili, L. |
format |
Article in Journal/Newspaper |
author |
FOSSI, M. C. CASINI, S. MARSILI, L. |
author_facet |
FOSSI, M. C. CASINI, S. MARSILI, L. |
author_sort |
FOSSI, M. C. |
title |
Endocrine Disruptors in Mediterranean Top Marine Predators |
title_short |
Endocrine Disruptors in Mediterranean Top Marine Predators |
title_full |
Endocrine Disruptors in Mediterranean Top Marine Predators |
title_fullStr |
Endocrine Disruptors in Mediterranean Top Marine Predators |
title_full_unstemmed |
Endocrine Disruptors in Mediterranean Top Marine Predators |
title_sort |
endocrine disruptors in mediterranean top marine predators |
publisher |
Ecomed Verlagsgesellschaft AG:Justus von Liebig Str 1, D 86899 Landsberg Germany:011 49 8191 1250, EMAIL: a.heinrich@ecomed.de, INTERNET: http://www.ecomed.de, Fax: 011 49 8191 125594 |
publishDate |
2006 |
url |
http://hdl.handle.net/11365/7749 https://doi.org/10.1065/espr2006.01.018 |
genre |
Balaenoptera physalus |
genre_facet |
Balaenoptera physalus |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/16758711 info:eu-repo/semantics/altIdentifier/wos/WOS:000237554100010 volume:13 issue:3 firstpage:204 lastpage:207 numberofpages:4 journal:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH INTERNATIONAL http://hdl.handle.net/11365/7749 doi:10.1065/espr2006.01.018 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-33646836959 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1065/espr2006.01.018 |
container_title |
Environmental Science and Pollution Research - International |
container_volume |
13 |
container_issue |
3 |
container_start_page |
204 |
op_container_end_page |
207 |
_version_ |
1790598270048796672 |