Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants
Various studies on Mediterranean cetaceans have revealed bioaccumulation of contaminants such as organochlorines (OCs) and heavy metals. The susceptibility of these animals to organic pollutants and the relationship between bioaccumulation and population decline las in the case of Delphinus delphis)...
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Online Access: | http://hdl.handle.net/11365/41091 https://doi.org/10.1016/S0141-1136(00)00127-6 |
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ftunivsiena:oai:usiena-air.unisi.it:11365/41091 2024-04-14T08:09:30+00:00 Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants FOSSI, M. C. MARSILI, L. NERI, G. CASINI, S. BEARZI, G. ZANARDELLI, M. PANIGADA, S. Fossi, M. C. Marsili, L. Neri, G. Casini, S. Bearzi, G. Zanardelli, M. Panigada, S. 2000 STAMPA http://hdl.handle.net/11365/41091 https://doi.org/10.1016/S0141-1136(00)00127-6 eng eng info:eu-repo/semantics/altIdentifier/pmid/11460743 info:eu-repo/semantics/altIdentifier/wos/WOS:000165486700080 volume:50 issue:1-5 firstpage:517 lastpage:521 numberofpages:5 journal:MARINE ENVIRONMENTAL RESEARCH http://hdl.handle.net/11365/41091 doi:10.1016/S0141-1136(00)00127-6 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0033734944 info:eu-repo/semantics/closedAccess marine mammal Mediterranean Sea non-destructive biomarker skin biopsy BPMO activity cell culture info:eu-repo/semantics/article 2000 ftunivsiena https://doi.org/10.1016/S0141-1136(00)00127-6 2024-03-21T15:55:33Z Various studies on Mediterranean cetaceans have revealed bioaccumulation of contaminants such as organochlorines (OCs) and heavy metals. The susceptibility of these animals to organic pollutants and the relationship between bioaccumulation and population decline las in the case of Delphinus delphis) are unexplored fields. In this study, we used a nondestructive approach (skin biopsy) to explore OC bioaccumulation processes and mixed-function oxidase activity (BPMO) in four species of cetaceans: striped dolphin (Stenella coeruleoalba), bottlenose dolphin (Tursiops truncatus), common dolphin (D. delphis) and fin whale (Balaenoptera physalus). Significant differences in BPMO induction and OC levels were found between odontocetes and mysticetes, the former having mixed-function oxidase activities four times higher than the latter, binding with levels of OCs one order of magnitude higher in odontocetes. A significant correlation (P < 0.05) between BPMO activities and OC levels was found in B. physalus. In an ongoing project, fibroblast cultures have been used as an alternative in vitro method of evaluating interspecies susceptibility to contaminants such as OCs and polycyclic aromatic hydrocarbons (PAHs). These results suggest that cetacean skin biopsies are a powerful non-invasive tool for assessing ecotoxicological risk to Mediterranean marine mammals species. Article in Journal/Newspaper Balaenoptera physalus Fin whale Università degli Studi di Siena: USiena air Marine Environmental Research 50 1-5 517 521 |
institution |
Open Polar |
collection |
Università degli Studi di Siena: USiena air |
op_collection_id |
ftunivsiena |
language |
English |
topic |
marine mammal Mediterranean Sea non-destructive biomarker skin biopsy BPMO activity cell culture |
spellingShingle |
marine mammal Mediterranean Sea non-destructive biomarker skin biopsy BPMO activity cell culture FOSSI, M. C. MARSILI, L. NERI, G. CASINI, S. BEARZI, G. ZANARDELLI, M. PANIGADA, S. Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
topic_facet |
marine mammal Mediterranean Sea non-destructive biomarker skin biopsy BPMO activity cell culture |
description |
Various studies on Mediterranean cetaceans have revealed bioaccumulation of contaminants such as organochlorines (OCs) and heavy metals. The susceptibility of these animals to organic pollutants and the relationship between bioaccumulation and population decline las in the case of Delphinus delphis) are unexplored fields. In this study, we used a nondestructive approach (skin biopsy) to explore OC bioaccumulation processes and mixed-function oxidase activity (BPMO) in four species of cetaceans: striped dolphin (Stenella coeruleoalba), bottlenose dolphin (Tursiops truncatus), common dolphin (D. delphis) and fin whale (Balaenoptera physalus). Significant differences in BPMO induction and OC levels were found between odontocetes and mysticetes, the former having mixed-function oxidase activities four times higher than the latter, binding with levels of OCs one order of magnitude higher in odontocetes. A significant correlation (P < 0.05) between BPMO activities and OC levels was found in B. physalus. In an ongoing project, fibroblast cultures have been used as an alternative in vitro method of evaluating interspecies susceptibility to contaminants such as OCs and polycyclic aromatic hydrocarbons (PAHs). These results suggest that cetacean skin biopsies are a powerful non-invasive tool for assessing ecotoxicological risk to Mediterranean marine mammals species. |
author2 |
Fossi, M. C. Marsili, L. Neri, G. Casini, S. Bearzi, G. Zanardelli, M. Panigada, S. |
format |
Article in Journal/Newspaper |
author |
FOSSI, M. C. MARSILI, L. NERI, G. CASINI, S. BEARZI, G. ZANARDELLI, M. PANIGADA, S. |
author_facet |
FOSSI, M. C. MARSILI, L. NERI, G. CASINI, S. BEARZI, G. ZANARDELLI, M. PANIGADA, S. |
author_sort |
FOSSI, M. C. |
title |
Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
title_short |
Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
title_full |
Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
title_fullStr |
Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
title_full_unstemmed |
Skin biopsy of Mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
title_sort |
skin biopsy of mediterranean cetaceans in the investigation of interspecies susceptibility to xenobiotic contaminants |
publishDate |
2000 |
url |
http://hdl.handle.net/11365/41091 https://doi.org/10.1016/S0141-1136(00)00127-6 |
genre |
Balaenoptera physalus Fin whale |
genre_facet |
Balaenoptera physalus Fin whale |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/11460743 info:eu-repo/semantics/altIdentifier/wos/WOS:000165486700080 volume:50 issue:1-5 firstpage:517 lastpage:521 numberofpages:5 journal:MARINE ENVIRONMENTAL RESEARCH http://hdl.handle.net/11365/41091 doi:10.1016/S0141-1136(00)00127-6 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0033734944 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1016/S0141-1136(00)00127-6 |
container_title |
Marine Environmental Research |
container_volume |
50 |
container_issue |
1-5 |
container_start_page |
517 |
op_container_end_page |
521 |
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1796306994036998144 |