Ancient population genomics and the study of evolution

• Published in: Philosophical Transactions of the Royal Society B: Biological Sciences
• Main Authors: Parks, M, Subramanian, Sankar, Baroni, C, Salvatore, M C, Zhang, G, Millar, C D, Lambert, D M
• Format: Article in Journal/Newspaper
• Language: English
• Published: Royal Society Publishing 2015
• Subjects: FoR 06 (Biological Sciences); FoR 11 (Medical and Health Sciences); Adélie penguin; ancient DNA; evolutionary rates; population genomics; Antarc*; Antarctica; permafrost; Pygoscelis adeliae
• Online Access: https://doi.org/10.1098/rstb.2013.0381

Recently, the study of ancient DNA (aDNA) has been greatly enhanced by the development of second-generation DNA sequencing technologies and targeted enrichment strategies. These developments have allowed the recovery of several complete ancient genomes, a result that would have been considered virtually impossible only a decade ago. Prior to these developments, aDNA research was largely focused on the recovery of short DNA sequences and their use in the study of phylogenetic relationships, molecular rates, species identification and population structure. However, it is now possible to sequence a large number of modern and ancient complete genomes from a single species and thereby study the genomic patterns of evolutionary change over time. Such a study would herald the beginnings of ancient population genomics and its use in the study of evolution. Species that are amenable to such large-scale studies warrant increased research effort. We report here progress on a population genomic study of the Adélie penguin (Pygoscelis adeliae). This species is ideally suited to ancient population genomic research because both modern and ancient samples are abundant in the permafrost conditions of Antarctica. This species will enable us to directly address many of the fundamental questions in ecology and evolution. © 2014 The Author(s) Published by the Royal Society. All rights reserved.