Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia
Background: Equine influenza virus (EIV) is considered enzootic in Europe (except Iceland), Asia, North Africa, and North and South America. When EIV outbreaks occur they may severely impact the equine and tourist industries. Australia faced its first EIV outbreak beginning in August of 2007. The ou...
Published in: | Journal of Clinical Virology |
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Online Access: | https://doi.org/10.1016/j.jcv.2013.11.011 |
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ftunivscoast:usc:11891 2023-05-15T16:51:47+02:00 Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia Burnell, F Holmes, M A Roiko, A H Lowe, J B Heil, Gary L White, Sarah K Gray, Gregory C 2014 https://doi.org/10.1016/j.jcv.2013.11.011 eng eng Elsevier BV usc:11891 URN:ISSN: 1386-6532 FoR 1103 (Clinical Sciences) FoR 0605 (Microbiology) FoR 1108 (Medical Microbiology) influenza A virus equine zoonoses seroepidemiologic studies epidemiology prospective studies Journal Article 2014 ftunivscoast https://doi.org/10.1016/j.jcv.2013.11.011 2019-02-11T23:27:04Z Background: Equine influenza virus (EIV) is considered enzootic in Europe (except Iceland), Asia, North Africa, and North and South America. When EIV outbreaks occur they may severely impact the equine and tourist industries. Australia faced its first EIV outbreak beginning in August of 2007. The outbreak was concentrated in New South Wales and Queensland, with more than 1400 confirmed EIV infections in horses during the first month. Rapid response from the equine industry and the federal government was successful and Australia was declared free from EIV by the end of 2007. Objectives This cross-sectional study was designed to examine associations between exposure to EIV-infected horses and evidence of EIV infection in humans. Study design Employing informed consent, between October 2007 and April 2008, 100 subjects (89 with horse exposures and 11 non-exposed) were enrolled during equine events and at the University of the Sunshine Coast. All subjects provided a blood sample and were asked to complete an online questionnaire including health history, animal exposure and demographic information. Sera samples were tested for the presence of antibodies against two H3N8 EIV strains using microneutralization, hemagglutination inhibition, and enzyme-linked lectin assays. Results Evidence for H3N8 infection was sparse, with only 9 study participants having any indication of H3N8 infection and the seroreactivity seen was low and easily explained by cross-reactions against human influenza strains or vaccines. Conclusions These data provide little evidence to support the premise that EIV infections occurred among humans exposed to EIV-infected horses during the 2007 Australian epizootic. Article in Journal/Newspaper Iceland University of the Sunshine Coast, Queensland, Australia: COAST Research Database Queensland Journal of Clinical Virology 59 2 100 103 |
institution |
Open Polar |
collection |
University of the Sunshine Coast, Queensland, Australia: COAST Research Database |
op_collection_id |
ftunivscoast |
language |
English |
topic |
FoR 1103 (Clinical Sciences) FoR 0605 (Microbiology) FoR 1108 (Medical Microbiology) influenza A virus equine zoonoses seroepidemiologic studies epidemiology prospective studies |
spellingShingle |
FoR 1103 (Clinical Sciences) FoR 0605 (Microbiology) FoR 1108 (Medical Microbiology) influenza A virus equine zoonoses seroepidemiologic studies epidemiology prospective studies Burnell, F Holmes, M A Roiko, A H Lowe, J B Heil, Gary L White, Sarah K Gray, Gregory C Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
topic_facet |
FoR 1103 (Clinical Sciences) FoR 0605 (Microbiology) FoR 1108 (Medical Microbiology) influenza A virus equine zoonoses seroepidemiologic studies epidemiology prospective studies |
description |
Background: Equine influenza virus (EIV) is considered enzootic in Europe (except Iceland), Asia, North Africa, and North and South America. When EIV outbreaks occur they may severely impact the equine and tourist industries. Australia faced its first EIV outbreak beginning in August of 2007. The outbreak was concentrated in New South Wales and Queensland, with more than 1400 confirmed EIV infections in horses during the first month. Rapid response from the equine industry and the federal government was successful and Australia was declared free from EIV by the end of 2007. Objectives This cross-sectional study was designed to examine associations between exposure to EIV-infected horses and evidence of EIV infection in humans. Study design Employing informed consent, between October 2007 and April 2008, 100 subjects (89 with horse exposures and 11 non-exposed) were enrolled during equine events and at the University of the Sunshine Coast. All subjects provided a blood sample and were asked to complete an online questionnaire including health history, animal exposure and demographic information. Sera samples were tested for the presence of antibodies against two H3N8 EIV strains using microneutralization, hemagglutination inhibition, and enzyme-linked lectin assays. Results Evidence for H3N8 infection was sparse, with only 9 study participants having any indication of H3N8 infection and the seroreactivity seen was low and easily explained by cross-reactions against human influenza strains or vaccines. Conclusions These data provide little evidence to support the premise that EIV infections occurred among humans exposed to EIV-infected horses during the 2007 Australian epizootic. |
format |
Article in Journal/Newspaper |
author |
Burnell, F Holmes, M A Roiko, A H Lowe, J B Heil, Gary L White, Sarah K Gray, Gregory C |
author_facet |
Burnell, F Holmes, M A Roiko, A H Lowe, J B Heil, Gary L White, Sarah K Gray, Gregory C |
author_sort |
Burnell, F |
title |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_short |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_full |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_fullStr |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_full_unstemmed |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_sort |
little evidence of human infection with equine influenza during the 2007 epizootic, queensland, australia |
publisher |
Elsevier BV |
publishDate |
2014 |
url |
https://doi.org/10.1016/j.jcv.2013.11.011 |
geographic |
Queensland |
geographic_facet |
Queensland |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
usc:11891 URN:ISSN: 1386-6532 |
op_doi |
https://doi.org/10.1016/j.jcv.2013.11.011 |
container_title |
Journal of Clinical Virology |
container_volume |
59 |
container_issue |
2 |
container_start_page |
100 |
op_container_end_page |
103 |
_version_ |
1766041885357375488 |