Phaeurus antarcticus and its endophytic fungi: chemical diversity of a hidden pharmacy underneath the Antarctic Ocean

• Main Author: Santos, Gustavo Souza dos
• Other Authors: Debonsi, Hosana Maria, Edrada-ebel, Ru Angelie
• Format: Doctoral or Postdoctoral Thesis
• Language: English
• Published: Biblioteca Digital de Teses e Dissertações da USP 2022
• Subjects: Produtos naturais marinhos; Macroalgas antárticas; Fungos antárticos; Fotoproteção; Doenças negligenciadas; Atividade imunomoduladora; Antimicrobianos; Metabolômica; Neglected diseases; Metabolomics; Photoprotection; Marine natural products; Immunomodulatory activity; Antimicrobials; Antarctic seaweed; Antarctic fungi; Antarctic; The Antarctic; Antarctic Ocean; Sob’; Antarc*; antarcticus
• Online Access: https://www.teses.usp.br/teses/disponiveis/60/60138/tde-20072023-113231/; https://doi.org/10.11606/T.60.2022.tde-20072023-113231

Chapter I: The chemical profile and antibacterial, antiparasitic, and insecticidal activities of the seaweed P. antarcticus were investigated. The hexane extract (HX) and its fractions exhibited selective antibacterial activity against Staphylococcus aureus. Fractions HX-FC and HX-FD showed the high...