Production of L-asparaginase of pharmaceutical nterest from yeasts isolated from the Antarctic continent

• Main Author: Moguel, Ignacio Sánchez
• Other Authors: Pessoa Junior, Adalberto
• Format: Doctoral or Postdoctoral Thesis
• Language: English
• Published: Biblioteca Digital de Teses e Dissertações da USP 2018
• Subjects: Acumulação de lipídios; Leucosporidium scottii; L-asparginase; Produção; DoE; Caracterização; Biorreator; Purificação; Levedura psicotrolerizante; Production; Psychrotolerant yeast; Lipid accumulation; Characterization; Bioreactor; Purification; Antarctic; Antarctic Peninsula; Sob’; The Antarctic; Antarc*; Antártica
• Online Access: http://www.teses.usp.br/teses/disponiveis/9/9134/tde-18062018-112633/; https://doi.org/10.11606/T.9.2018.tde-18062018-112633

The L-asparaginase (ASNase) obtained from yeasts species has been poorly studied and a new yeast ASNase could be an alternative to minimize the side effect in the treatment of lymphoblastic leukemia. The Antarctic ecosystems have a great potential to obtain novel enzymes produced from psychrophilic...