Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience
Introduction: Recently a novel cryoballoon system (POLARx, Boston Scientific) became available for the treatment of atrial fibrillation. This cryoballoon is comparable with Arctic Front Advance Pro (AFA-Pro, Medtronic), however, it maintains a constant balloon pressure. We compared the procedural ef...
Published in: | Journal of Cardiovascular Electrophysiology |
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ftunivrotterdam:oai:repub.eur.nl:134391 2023-07-16T03:57:06+02:00 Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience Yap, S.-C. (Sing-Chien) Anic, A. (Ante) Breskovic, T. (Toni) Haas, A. (Annika) Bhagwandien, R.E. (Rohit) Jurisic, Z. (Zrinka) Szili-Török, T. (Tamás) Luik, A. (Armin) 2021-01-25 application/pdf http://repub.eur.nl/pub/134391 https://doi.org/10.1111/jce.14915 en eng http://repub.eur.nl/pub/134391 doi:10.1111/jce.14915 urn:hdl:1765/134391 info:eu-repo/semantics/openAccess Journal of Cardiovascular Electrophysiology atrial fibrillation catheter ablation cryoablation cryoballoon pulmonary vein isolation info:eu-repo/semantics/article 2021 ftunivrotterdam https://doi.org/10.1111/jce.14915 2023-06-26T22:22:05Z Introduction: Recently a novel cryoballoon system (POLARx, Boston Scientific) became available for the treatment of atrial fibrillation. This cryoballoon is comparable with Arctic Front Advance Pro (AFA-Pro, Medtronic), however, it maintains a constant balloon pressure. We compared the procedural efficacy and biophysical characteristics of both systems. Methods: One hundred and ten consecutive patients who underwent first-time cryoballoon ablation (POLARx: n = 57; AFA-Pro: n = 53) were included in this prospective cohort study. Results: Acute isolation was achieved in 99.8% of all pulmonary veins (POLARx: 99.5% vs. AFA-Pro: 100%, p = 1.00). Total procedure time (81 vs. 67 min, p <.001) and balloon in body time (51 vs. 35 min, p <.001) were longer with POLARx. After a learning curve, these times were similar. Cryoablation with POLARx was associated with shorter time to balloon temperature −30°C (27 vs. 31 s, p <.001) and −40°C (32 vs. 54 s, p <.001), lower balloon nadir temperature (−55°C vs. −47°C, p <.001), and longer thawing time till 0°C (16 vs. 9 s, p <.001). There were no differences in time-to-isolation (TTI; POLARx: 45 s vs. AFA-Pro 43 s, p =.441), however, POLARx was associated with a lower balloon temperature at TTI (−46°C vs. −37°C, p <.001). Factors associated with acute isolation differed between groups. The incidence of phrenic nerve palsy was comparable (POLARx: 3.5% vs. AFA-Pro: 3.7%). Conclusion: The novel cryoballoon is comparable to AFA-Pro and requires only a short learning curve to get used to the slightly different handling. It was associated with faster cooling rates and lower b Article in Journal/Newspaper Arctic RePub - Publications from Erasmus University, Rotterdam Arctic Journal of Cardiovascular Electrophysiology 32 3 580 587 |
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Open Polar |
collection |
RePub - Publications from Erasmus University, Rotterdam |
op_collection_id |
ftunivrotterdam |
language |
English |
topic |
atrial fibrillation catheter ablation cryoablation cryoballoon pulmonary vein isolation |
spellingShingle |
atrial fibrillation catheter ablation cryoablation cryoballoon pulmonary vein isolation Yap, S.-C. (Sing-Chien) Anic, A. (Ante) Breskovic, T. (Toni) Haas, A. (Annika) Bhagwandien, R.E. (Rohit) Jurisic, Z. (Zrinka) Szili-Török, T. (Tamás) Luik, A. (Armin) Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience |
topic_facet |
atrial fibrillation catheter ablation cryoablation cryoballoon pulmonary vein isolation |
description |
Introduction: Recently a novel cryoballoon system (POLARx, Boston Scientific) became available for the treatment of atrial fibrillation. This cryoballoon is comparable with Arctic Front Advance Pro (AFA-Pro, Medtronic), however, it maintains a constant balloon pressure. We compared the procedural efficacy and biophysical characteristics of both systems. Methods: One hundred and ten consecutive patients who underwent first-time cryoballoon ablation (POLARx: n = 57; AFA-Pro: n = 53) were included in this prospective cohort study. Results: Acute isolation was achieved in 99.8% of all pulmonary veins (POLARx: 99.5% vs. AFA-Pro: 100%, p = 1.00). Total procedure time (81 vs. 67 min, p <.001) and balloon in body time (51 vs. 35 min, p <.001) were longer with POLARx. After a learning curve, these times were similar. Cryoablation with POLARx was associated with shorter time to balloon temperature −30°C (27 vs. 31 s, p <.001) and −40°C (32 vs. 54 s, p <.001), lower balloon nadir temperature (−55°C vs. −47°C, p <.001), and longer thawing time till 0°C (16 vs. 9 s, p <.001). There were no differences in time-to-isolation (TTI; POLARx: 45 s vs. AFA-Pro 43 s, p =.441), however, POLARx was associated with a lower balloon temperature at TTI (−46°C vs. −37°C, p <.001). Factors associated with acute isolation differed between groups. The incidence of phrenic nerve palsy was comparable (POLARx: 3.5% vs. AFA-Pro: 3.7%). Conclusion: The novel cryoballoon is comparable to AFA-Pro and requires only a short learning curve to get used to the slightly different handling. It was associated with faster cooling rates and lower b |
format |
Article in Journal/Newspaper |
author |
Yap, S.-C. (Sing-Chien) Anic, A. (Ante) Breskovic, T. (Toni) Haas, A. (Annika) Bhagwandien, R.E. (Rohit) Jurisic, Z. (Zrinka) Szili-Török, T. (Tamás) Luik, A. (Armin) |
author_facet |
Yap, S.-C. (Sing-Chien) Anic, A. (Ante) Breskovic, T. (Toni) Haas, A. (Annika) Bhagwandien, R.E. (Rohit) Jurisic, Z. (Zrinka) Szili-Török, T. (Tamás) Luik, A. (Armin) |
author_sort |
Yap, S.-C. (Sing-Chien) |
title |
Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience |
title_short |
Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience |
title_full |
Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience |
title_fullStr |
Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience |
title_full_unstemmed |
Comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: Insights from an initial multicenter experience |
title_sort |
comparison of procedural efficacy and biophysical parameters between two competing cryoballoon technologies for pulmonary vein isolation: insights from an initial multicenter experience |
publishDate |
2021 |
url |
http://repub.eur.nl/pub/134391 https://doi.org/10.1111/jce.14915 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Cardiovascular Electrophysiology |
op_relation |
http://repub.eur.nl/pub/134391 doi:10.1111/jce.14915 urn:hdl:1765/134391 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1111/jce.14915 |
container_title |
Journal of Cardiovascular Electrophysiology |
container_volume |
32 |
container_issue |
3 |
container_start_page |
580 |
op_container_end_page |
587 |
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1771543619114631168 |