Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia
Chagas disease is a zoonotic infection widely distributed in tropical and subtropical regions of America, including more than 50% of the Colombian territory. In the last years, an increase of outbreaks of acute Chagas disease has been observed in the east of the country due to environmental changes...
Published in: | Preventive Veterinary Medicine |
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Language: | English |
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Elsevier B.V.
2017
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ftunivrosario:oai:repository.urosario.edu.co:10336/22853 2023-05-15T15:50:00+02:00 Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia Jaimes-Dueñez J. Triana-Chávez O. Cantillo-Barraza O. Hernández C. Ramírez, Juan David Góngora-Orjuela A. 2017 application/pdf https://repository.urosario.edu.co/handle/10336/22853 https://doi.org/10.1016/j.prevetmed.2017.03.009 eng eng Elsevier B.V. 1675877 https://repository.urosario.edu.co/handle/10336/22853 https://doi.org/10.1016/j.prevetmed.2017.03.009 info:eu-repo/semantics/openAccess instname:Universidad del Rosario Cell nucleus DNA Kinetoplast DNA Protozoal DNA Satellite DNA Acute disease Adult Article Chagas disease Colombia Controlled study Disease transmission Dog Dog disease Epidemic Female Genotype Male Microorganism detection Molecular diagnosis Nonhuman Puppy Serology Seroprevalence Young adult Animal Disease carrier Dog Diseases Isolation and purification Prevalence Risk factor Transmission Trypanosoma cruzi Veterinary Animals Disease Outbreaks Disease Reservoirs Dogs Risk Factors Cumaral info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2017 ftunivrosario https://doi.org/10.1016/j.prevetmed.2017.03.009 2022-08-01T07:08:07Z Chagas disease is a zoonotic infection widely distributed in tropical and subtropical regions of America, including more than 50% of the Colombian territory. In the last years, an increase of outbreaks of acute Chagas disease has been observed in the east of the country due to environmental changes and mammal movements toward human settlements. Given the importance of dogs (Canis lupus familiaris) as reservoir hosts and sentinels of Trypanosoma cruzi infection across different regions of America, in this study we reported a serological and molecular detection of T. cruzi infection in 242 dogs from an endemic area of Meta department (East of Colombia), with recent emergence of acute Chagas disease outbreaks. The distribution of T. cruzi infection in dogs was not homogeneous, ranging from 0–41.4% and 0–5.1% in different sampling sectors, through serological (ELISA/IFAT) and molecular methods (conventional and real time PCR), respectively. Statistical analysis indicated that dog infection was associated with specific sampling sectors. Our results show a moderate seroprevalence of infection and active circulation of T. cruzi in dogs from this zone, which suggest areas with potential risk of infection to human that must be taken into consideration when Chagas disease control programs need to be implemented. © 2017 Elsevier B.V. Article in Journal/Newspaper Canis lupus Universidad del Rosario, Bogotá: E-docUR Preventive Veterinary Medicine 141 1 6 |
institution |
Open Polar |
collection |
Universidad del Rosario, Bogotá: E-docUR |
op_collection_id |
ftunivrosario |
language |
English |
topic |
Cell nucleus DNA Kinetoplast DNA Protozoal DNA Satellite DNA Acute disease Adult Article Chagas disease Colombia Controlled study Disease transmission Dog Dog disease Epidemic Female Genotype Male Microorganism detection Molecular diagnosis Nonhuman Puppy Serology Seroprevalence Young adult Animal Disease carrier Dog Diseases Isolation and purification Prevalence Risk factor Transmission Trypanosoma cruzi Veterinary Animals Disease Outbreaks Disease Reservoirs Dogs Risk Factors Cumaral |
spellingShingle |
Cell nucleus DNA Kinetoplast DNA Protozoal DNA Satellite DNA Acute disease Adult Article Chagas disease Colombia Controlled study Disease transmission Dog Dog disease Epidemic Female Genotype Male Microorganism detection Molecular diagnosis Nonhuman Puppy Serology Seroprevalence Young adult Animal Disease carrier Dog Diseases Isolation and purification Prevalence Risk factor Transmission Trypanosoma cruzi Veterinary Animals Disease Outbreaks Disease Reservoirs Dogs Risk Factors Cumaral Jaimes-Dueñez J. Triana-Chávez O. Cantillo-Barraza O. Hernández C. Ramírez, Juan David Góngora-Orjuela A. Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia |
topic_facet |
Cell nucleus DNA Kinetoplast DNA Protozoal DNA Satellite DNA Acute disease Adult Article Chagas disease Colombia Controlled study Disease transmission Dog Dog disease Epidemic Female Genotype Male Microorganism detection Molecular diagnosis Nonhuman Puppy Serology Seroprevalence Young adult Animal Disease carrier Dog Diseases Isolation and purification Prevalence Risk factor Transmission Trypanosoma cruzi Veterinary Animals Disease Outbreaks Disease Reservoirs Dogs Risk Factors Cumaral |
description |
Chagas disease is a zoonotic infection widely distributed in tropical and subtropical regions of America, including more than 50% of the Colombian territory. In the last years, an increase of outbreaks of acute Chagas disease has been observed in the east of the country due to environmental changes and mammal movements toward human settlements. Given the importance of dogs (Canis lupus familiaris) as reservoir hosts and sentinels of Trypanosoma cruzi infection across different regions of America, in this study we reported a serological and molecular detection of T. cruzi infection in 242 dogs from an endemic area of Meta department (East of Colombia), with recent emergence of acute Chagas disease outbreaks. The distribution of T. cruzi infection in dogs was not homogeneous, ranging from 0–41.4% and 0–5.1% in different sampling sectors, through serological (ELISA/IFAT) and molecular methods (conventional and real time PCR), respectively. Statistical analysis indicated that dog infection was associated with specific sampling sectors. Our results show a moderate seroprevalence of infection and active circulation of T. cruzi in dogs from this zone, which suggest areas with potential risk of infection to human that must be taken into consideration when Chagas disease control programs need to be implemented. © 2017 Elsevier B.V. |
format |
Article in Journal/Newspaper |
author |
Jaimes-Dueñez J. Triana-Chávez O. Cantillo-Barraza O. Hernández C. Ramírez, Juan David Góngora-Orjuela A. |
author_facet |
Jaimes-Dueñez J. Triana-Chávez O. Cantillo-Barraza O. Hernández C. Ramírez, Juan David Góngora-Orjuela A. |
author_sort |
Jaimes-Dueñez J. |
title |
Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia |
title_short |
Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia |
title_full |
Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia |
title_fullStr |
Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia |
title_full_unstemmed |
Molecular and serological detection of Trypanosoma cruzi in dogs (Canis lupus familiaris) suggests potential transmission risk in areas of recent acute Chagas disease outbreaks in Colombia |
title_sort |
molecular and serological detection of trypanosoma cruzi in dogs (canis lupus familiaris) suggests potential transmission risk in areas of recent acute chagas disease outbreaks in colombia |
publisher |
Elsevier B.V. |
publishDate |
2017 |
url |
https://repository.urosario.edu.co/handle/10336/22853 https://doi.org/10.1016/j.prevetmed.2017.03.009 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_source |
instname:Universidad del Rosario |
op_relation |
1675877 https://repository.urosario.edu.co/handle/10336/22853 https://doi.org/10.1016/j.prevetmed.2017.03.009 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1016/j.prevetmed.2017.03.009 |
container_title |
Preventive Veterinary Medicine |
container_volume |
141 |
container_start_page |
1 |
op_container_end_page |
6 |
_version_ |
1766385000555479040 |