Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO
Proton caged compounds exhibit a characteristic behavior when directly dosed into cells or being coupled to gold nanoparticles prior to the dosing. When irradiated in the near ultraviolet region, they release protons that interact with intracellular HCO3  to yield H2CO3. The dissociation of...
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ftunivromairis:oai:iris.uniroma1.it:11573/856254 2024-09-15T18:01:38+00:00 Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO Carbone, Marilena SABBATELLA, GIANFRANCO Antonaroli, Simonetta Remita, Hynd ORLANDO, Viviana BIAGIONI, Stefano NUCARA, Alessandro Carbone, Marilena Sabbatella, Gianfranco Antonaroli, Simonetta Remita, Hynd Orlando, Viviana Biagioni, Stefano Nucara, Alessandro 2016 ELETTRONICO https://hdl.handle.net/11573/856254 https://doi.org/10.1016/j.dib.2015.12.032 eng eng info:eu-repo/semantics/altIdentifier/wos/WOS:000453162100118 volume:6 firstpage:745 lastpage:749 numberofpages:5 journal:DATA IN BRIEF https://hdl.handle.net/11573/856254 doi:10.1016/j.dib.2015.12.032 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84964200060 Proton caged compound DMSO Intracellular proton release info:eu-repo/semantics/article 2016 ftunivromairis https://doi.org/10.1016/j.dib.2015.12.032 2024-07-01T23:39:29Z Proton caged compounds exhibit a characteristic behavior when directly dosed into cells or being coupled to gold nanoparticles prior to the dosing. When irradiated in the near ultraviolet region, they release protons that interact with intracellular HCO3  to yield H2CO3. The dissociation of carbonic acid, then, releases CO2 that can be distinctively singled out in infrared spectra. In the process of searching a pathway to augment the intracellular uptake of proton caged compounds, we probed the association of 1-(2-nitrophenyl)-ethylhexadecyl sulfonate (HDNS) with DMSO, an agent to enhance the membrane permeability. We found out a different UV-induced protonation mechanism that opens up to new conduits of employing of proton caged compounds. Here, we report the infrared data we collected in this set of experiments. Article in Journal/Newspaper Carbonic acid Sapienza Università di Roma: CINECA IRIS Data in Brief 6 745 749 |
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Sapienza Università di Roma: CINECA IRIS |
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ftunivromairis |
language |
English |
topic |
Proton caged compound DMSO Intracellular proton release |
spellingShingle |
Proton caged compound DMSO Intracellular proton release Carbone, Marilena SABBATELLA, GIANFRANCO Antonaroli, Simonetta Remita, Hynd ORLANDO, Viviana BIAGIONI, Stefano NUCARA, Alessandro Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO |
topic_facet |
Proton caged compound DMSO Intracellular proton release |
description |
Proton caged compounds exhibit a characteristic behavior when directly dosed into cells or being coupled to gold nanoparticles prior to the dosing. When irradiated in the near ultraviolet region, they release protons that interact with intracellular HCO3  to yield H2CO3. The dissociation of carbonic acid, then, releases CO2 that can be distinctively singled out in infrared spectra. In the process of searching a pathway to augment the intracellular uptake of proton caged compounds, we probed the association of 1-(2-nitrophenyl)-ethylhexadecyl sulfonate (HDNS) with DMSO, an agent to enhance the membrane permeability. We found out a different UV-induced protonation mechanism that opens up to new conduits of employing of proton caged compounds. Here, we report the infrared data we collected in this set of experiments. |
author2 |
Carbone, Marilena Sabbatella, Gianfranco Antonaroli, Simonetta Remita, Hynd Orlando, Viviana Biagioni, Stefano Nucara, Alessandro |
format |
Article in Journal/Newspaper |
author |
Carbone, Marilena SABBATELLA, GIANFRANCO Antonaroli, Simonetta Remita, Hynd ORLANDO, Viviana BIAGIONI, Stefano NUCARA, Alessandro |
author_facet |
Carbone, Marilena SABBATELLA, GIANFRANCO Antonaroli, Simonetta Remita, Hynd ORLANDO, Viviana BIAGIONI, Stefano NUCARA, Alessandro |
author_sort |
Carbone, Marilena |
title |
Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO |
title_short |
Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO |
title_full |
Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO |
title_fullStr |
Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO |
title_full_unstemmed |
Exogenous control over intracellular acidification: Enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with DMSO |
title_sort |
exogenous control over intracellular acidification: enhancement via proton caged compounds coupled to gold nanoparticles and an alternative pathway with dmso |
publishDate |
2016 |
url |
https://hdl.handle.net/11573/856254 https://doi.org/10.1016/j.dib.2015.12.032 |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_relation |
info:eu-repo/semantics/altIdentifier/wos/WOS:000453162100118 volume:6 firstpage:745 lastpage:749 numberofpages:5 journal:DATA IN BRIEF https://hdl.handle.net/11573/856254 doi:10.1016/j.dib.2015.12.032 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84964200060 |
op_doi |
https://doi.org/10.1016/j.dib.2015.12.032 |
container_title |
Data in Brief |
container_volume |
6 |
container_start_page |
745 |
op_container_end_page |
749 |
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1810438737622990848 |