Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group

BackgroundPhylogenetic analyses of closely related species of mosquitoes are important for better understanding the evolution of traits contributing to transmission of vector-borne diseases. Six out of 41 dominant malaria vectors of the genus Anopheles in the world belong to the Maculipennis Group,...

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Published in:BMC Biology
Main Authors: Yurchenko, Andrey A, Naumenko, Anastasia N, Artemov, Gleb N, Karagodin, Dmitry A, Hodge, James M, Velichevskaya, Alena I, Kokhanenko, Alina A, Bondarenko, Semen M, Abai, Mohammad R, Kamali, Maryam, Gordeev, Mikhail I, Moskaev, Anton V, Caputo, Beniamino, Aghayan, Sargis A, Baricheva, Elina M, Stegniy, Vladimir N, Sharakhova, Maria V, Sharakhov, Igor V
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2023
Subjects:
Online Access:https://hdl.handle.net/11573/1680104
https://doi.org/10.1186/s12915-023-01538-w
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spelling ftunivromairis:oai:iris.uniroma1.it:11573/1680104 2024-02-04T09:59:16+01:00 Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group Yurchenko, Andrey A Naumenko, Anastasia N Artemov, Gleb N Karagodin, Dmitry A Hodge, James M Velichevskaya, Alena I Kokhanenko, Alina A Bondarenko, Semen M Abai, Mohammad R Kamali, Maryam Gordeev, Mikhail I Moskaev, Anton V Caputo, Beniamino Aghayan, Sargis A Baricheva, Elina M Stegniy, Vladimir N Sharakhova, Maria V Sharakhov, Igor V Yurchenko, Andrey A Naumenko, Anastasia N Artemov, Gleb N Karagodin, Dmitry A Hodge, James M Velichevskaya, Alena I Kokhanenko, Alina A Bondarenko, Semen M Abai, Mohammad R Kamali, Maryam Gordeev, Mikhail I Moskaev, Anton V Caputo, Beniamino Aghayan, Sargis A Baricheva, Elina M Stegniy, Vladimir N Sharakhova, Maria V Sharakhov, Igor V 2023 https://hdl.handle.net/11573/1680104 https://doi.org/10.1186/s12915-023-01538-w eng eng BMC place:CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND info:eu-repo/semantics/altIdentifier/pmid/37032389 info:eu-repo/semantics/altIdentifier/wos/WOS:000964973000001 volume:21 issue:1 firstpage:1 lastpage:20 numberofpages:20 journal:BMC BIOLOGY https://hdl.handle.net/11573/1680104 doi:10.1186/s12915-023-01538-w info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85152165210 info:eu-repo/semantics/openAccess anophele chromosome introgression maculipennis subgroup malaria vector migration mosquitoe phylogenomic species radiation info:eu-repo/semantics/article 2023 ftunivromairis https://doi.org/10.1186/s12915-023-01538-w 2024-01-10T17:41:34Z BackgroundPhylogenetic analyses of closely related species of mosquitoes are important for better understanding the evolution of traits contributing to transmission of vector-borne diseases. Six out of 41 dominant malaria vectors of the genus Anopheles in the world belong to the Maculipennis Group, which is subdivided into two Nearctic subgroups (Freeborni and Quadrimaculatus) and one Palearctic (Maculipennis) subgroup. Although previous studies considered the Nearctic subgroups as ancestral, details about their relationship with the Palearctic subgroup, and their migration times and routes from North America to Eurasia remain controversial. The Palearctic species An. beklemishevi is currently included in the Nearctic Quadrimaculatus subgroup adding to the uncertainties in mosquito systematics.ResultsTo reconstruct historic relationships in the Maculipennis Group, we conducted a phylogenomic analysis of 11 Palearctic and 2 Nearctic species based on sequences of 1271 orthologous genes. The analysis indicated that the Palearctic species An. beklemishevi clusters together with other Eurasian species and represents a basal lineage among them. Also, An. beklemishevi is related more closely to An. freeborni, which inhabits the Western United States, rather than to An. quadrimaculatus, a species from the Eastern United States. The time-calibrated tree suggests a migration of mosquitoes in the Maculipennis Group from North America to Eurasia about 20-25 million years ago through the Bering Land Bridge. A Hybridcheck analysis demonstrated highly significant signatures of introgression events between allopatric species An. labranchiae and An. beklemishevi. The analysis also identified ancestral introgression events between An. sacharovi and its Nearctic relative An. freeborni despite their current geographic isolation. The reconstructed phylogeny suggests that vector competence and the ability to enter complete diapause during winter evolved independently in different lineages of the Maculipennis Group.ConclusionsOur ... Article in Journal/Newspaper Bering Land Bridge Sapienza Università di Roma: CINECA IRIS BMC Biology 21 1
institution Open Polar
collection Sapienza Università di Roma: CINECA IRIS
op_collection_id ftunivromairis
language English
topic anophele
chromosome
introgression
maculipennis subgroup
malaria vector
migration
mosquitoe
phylogenomic
species radiation
spellingShingle anophele
chromosome
introgression
maculipennis subgroup
malaria vector
migration
mosquitoe
phylogenomic
species radiation
Yurchenko, Andrey A
Naumenko, Anastasia N
Artemov, Gleb N
Karagodin, Dmitry A
Hodge, James M
Velichevskaya, Alena I
Kokhanenko, Alina A
Bondarenko, Semen M
Abai, Mohammad R
Kamali, Maryam
Gordeev, Mikhail I
Moskaev, Anton V
Caputo, Beniamino
Aghayan, Sargis A
Baricheva, Elina M
Stegniy, Vladimir N
Sharakhova, Maria V
Sharakhov, Igor V
Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group
topic_facet anophele
chromosome
introgression
maculipennis subgroup
malaria vector
migration
mosquitoe
phylogenomic
species radiation
description BackgroundPhylogenetic analyses of closely related species of mosquitoes are important for better understanding the evolution of traits contributing to transmission of vector-borne diseases. Six out of 41 dominant malaria vectors of the genus Anopheles in the world belong to the Maculipennis Group, which is subdivided into two Nearctic subgroups (Freeborni and Quadrimaculatus) and one Palearctic (Maculipennis) subgroup. Although previous studies considered the Nearctic subgroups as ancestral, details about their relationship with the Palearctic subgroup, and their migration times and routes from North America to Eurasia remain controversial. The Palearctic species An. beklemishevi is currently included in the Nearctic Quadrimaculatus subgroup adding to the uncertainties in mosquito systematics.ResultsTo reconstruct historic relationships in the Maculipennis Group, we conducted a phylogenomic analysis of 11 Palearctic and 2 Nearctic species based on sequences of 1271 orthologous genes. The analysis indicated that the Palearctic species An. beklemishevi clusters together with other Eurasian species and represents a basal lineage among them. Also, An. beklemishevi is related more closely to An. freeborni, which inhabits the Western United States, rather than to An. quadrimaculatus, a species from the Eastern United States. The time-calibrated tree suggests a migration of mosquitoes in the Maculipennis Group from North America to Eurasia about 20-25 million years ago through the Bering Land Bridge. A Hybridcheck analysis demonstrated highly significant signatures of introgression events between allopatric species An. labranchiae and An. beklemishevi. The analysis also identified ancestral introgression events between An. sacharovi and its Nearctic relative An. freeborni despite their current geographic isolation. The reconstructed phylogeny suggests that vector competence and the ability to enter complete diapause during winter evolved independently in different lineages of the Maculipennis Group.ConclusionsOur ...
author2 Yurchenko, Andrey A
Naumenko, Anastasia N
Artemov, Gleb N
Karagodin, Dmitry A
Hodge, James M
Velichevskaya, Alena I
Kokhanenko, Alina A
Bondarenko, Semen M
Abai, Mohammad R
Kamali, Maryam
Gordeev, Mikhail I
Moskaev, Anton V
Caputo, Beniamino
Aghayan, Sargis A
Baricheva, Elina M
Stegniy, Vladimir N
Sharakhova, Maria V
Sharakhov, Igor V
format Article in Journal/Newspaper
author Yurchenko, Andrey A
Naumenko, Anastasia N
Artemov, Gleb N
Karagodin, Dmitry A
Hodge, James M
Velichevskaya, Alena I
Kokhanenko, Alina A
Bondarenko, Semen M
Abai, Mohammad R
Kamali, Maryam
Gordeev, Mikhail I
Moskaev, Anton V
Caputo, Beniamino
Aghayan, Sargis A
Baricheva, Elina M
Stegniy, Vladimir N
Sharakhova, Maria V
Sharakhov, Igor V
author_facet Yurchenko, Andrey A
Naumenko, Anastasia N
Artemov, Gleb N
Karagodin, Dmitry A
Hodge, James M
Velichevskaya, Alena I
Kokhanenko, Alina A
Bondarenko, Semen M
Abai, Mohammad R
Kamali, Maryam
Gordeev, Mikhail I
Moskaev, Anton V
Caputo, Beniamino
Aghayan, Sargis A
Baricheva, Elina M
Stegniy, Vladimir N
Sharakhova, Maria V
Sharakhov, Igor V
author_sort Yurchenko, Andrey A
title Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group
title_short Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group
title_full Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group
title_fullStr Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group
title_full_unstemmed Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group
title_sort phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the maculipennis group
publisher BMC
publishDate 2023
url https://hdl.handle.net/11573/1680104
https://doi.org/10.1186/s12915-023-01538-w
genre Bering Land Bridge
genre_facet Bering Land Bridge
op_relation info:eu-repo/semantics/altIdentifier/pmid/37032389
info:eu-repo/semantics/altIdentifier/wos/WOS:000964973000001
volume:21
issue:1
firstpage:1
lastpage:20
numberofpages:20
journal:BMC BIOLOGY
https://hdl.handle.net/11573/1680104
doi:10.1186/s12915-023-01538-w
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85152165210
op_rights info:eu-repo/semantics/openAccess
op_doi https://doi.org/10.1186/s12915-023-01538-w
container_title BMC Biology
container_volume 21
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