Peroxynitrite scavenging by ferryl sperm whale myoglobin and human hemoglobin

• Published in: Biochemical and Biophysical Research Communications
• Main Authors: Ascenzi P., De Marinis E., di Masi A., Ciaccio C., Coletta M.
• Other Authors: Ascenzi, P., De Marinis, E., di Masi, A., Ciaccio, C., Coletta, M.
• Format: Article in Journal/Newspaper
• Language: English
• Published: ACADEMIC PRESS INC ELSEVIER SCIENCE 2009
• Subjects: Effect of CO; 2; Ferric hemoglobin formation; Ferric myoglobin formation; Ferryl hemoglobin reduction; Ferryl myoglobin reduction; Kinetic; Peroxynitrite scavenging; Animal; Hemoglobin; Human; Iron; Mice; Myoglobin; Oxidation-Reduction; Peroxynitrous Acid; Sperm Whale; Kon; Sperm whale
• Online Access: http://hdl.handle.net/11573/1409634; https://doi.org/10.1016/j.bbrc.2009.09.050

Globins protect from the oxidative and nitrosative cell damage. Here, kinetics of peroxynitrite scavenging by ferryl sperm whale myoglobin (Mb{single bond}Fe(IV){double bond, long}O) and human hemoglobin (Hb{single bond}Fe(IV){double bond, long}O), between pH 5.8 and 8.3 at 20.0 °C, are reported. In...