Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts.
International audience Toxoplasmosis is a major zoonosis, and its prevention requires multiple approaches due to the complex life-cycle of its causative agent, Toxoplasma gondii. Environmental contamination by oocysts is a key factor in the transmission of T. gondii to both humans and meat-producing...
Published in: | International Journal for Parasitology: Parasites and Wildlife |
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Main Authors: | , , , , , , , , |
Other Authors: | , , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
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HAL CCSD
2013
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Online Access: | https://hal.science/hal-00972560 https://doi.org/10.1016/j.ijppaw.2013.09.006 |
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Université de Reims Champagne-Ardenne: Archives Ouvertes (HAL) |
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ftunivreimsca |
language |
English |
topic |
[SDV]Life Sciences [q-bio] |
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[SDV]Life Sciences [q-bio] Afonso, Eve Germain, Estelle Poulle, Marie-Lazarine Ruette, Sandrine Devillard, Sébastien Say, Ludovic Villena, Isabelle Voutquenne-Nazabadioko, Laurence Gilot-Fromont, Emmanuelle Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. |
topic_facet |
[SDV]Life Sciences [q-bio] |
description |
International audience Toxoplasmosis is a major zoonosis, and its prevention requires multiple approaches due to the complex life-cycle of its causative agent, Toxoplasma gondii. Environmental contamination by oocysts is a key factor in the transmission of T. gondii to both humans and meat-producing animals; however, its spatial and temporal variations are poorly understood. We analysed the distribution of T. gondii seropositivity in a sample of 210 cats, including the European wildcat (Felis silvestris silvestris), the domestic cat (Felis silvestris catus) and their hybrids that were collected in Central and Eastern France between 1996 and 2006. We searched for spatial variability among communes and temporal variations among years to relate this variability to landscape and meteorological conditions, which can affect the population dynamics of rodent hosts and the survival of oocysts. The overall seroprevalence was 65.2% (95% CI: 58.6-71.4). As expected, adults were more often infected than young individuals, while the occurrence of infection was not related to cat genotypes. Seroprevalence correlated significantly with farm density and the North-Atlantic Oscillation index, which describes temporal variations of meteorological conditions at the continental scale. The highest seroprevalence values were obtained in areas with high farm densities and during years with cool and moist winters. These results suggest that both farming areas and years with cool and wet winters are associated with increased T. gondii seroprevalence in cats. As cat infection determines the environmental contamination by oocysts, climate and landscape characteristics should be taken into account to improve the risk analysis and prevention of T. gondii. |
author2 |
Laboratoire Chrono-environnement (UMR 6249) (LCE) Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC) Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC) Centre de Recherche et de Formation en Eco-éthologie (2C2A-CERFE) Université de Reims Champagne-Ardenne (URCA) Office National de la Chasse et de la Faune Sauvage, CNERA Prédateurs Animaux déprédateurs Ecologie et évolution des populations Département écologie évolutive LBBE Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE) Université Claude Bernard Lyon 1 (UCBL) Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL) Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE) Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS) Centre de formation et de recherche en environnement marin (CEFREM) Université de Perpignan Via Domitia (UPVD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS) Biodémographie évolutive |
format |
Article in Journal/Newspaper |
author |
Afonso, Eve Germain, Estelle Poulle, Marie-Lazarine Ruette, Sandrine Devillard, Sébastien Say, Ludovic Villena, Isabelle Voutquenne-Nazabadioko, Laurence Gilot-Fromont, Emmanuelle |
author_facet |
Afonso, Eve Germain, Estelle Poulle, Marie-Lazarine Ruette, Sandrine Devillard, Sébastien Say, Ludovic Villena, Isabelle Voutquenne-Nazabadioko, Laurence Gilot-Fromont, Emmanuelle |
author_sort |
Afonso, Eve |
title |
Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. |
title_short |
Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. |
title_full |
Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. |
title_fullStr |
Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. |
title_full_unstemmed |
Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. |
title_sort |
environmental determinants of spatial and temporal variations in the transmission of toxoplasma gondii in its definitive hosts. |
publisher |
HAL CCSD |
publishDate |
2013 |
url |
https://hal.science/hal-00972560 https://doi.org/10.1016/j.ijppaw.2013.09.006 |
genre |
North Atlantic North Atlantic oscillation |
genre_facet |
North Atlantic North Atlantic oscillation |
op_source |
ISSN: 2213-2244 International Journal for Parasitology: Parasites and Wildlife https://hal.science/hal-00972560 International Journal for Parasitology: Parasites and Wildlife, 2013, 2, pp.278-85. ⟨10.1016/j.ijppaw.2013.09.006⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijppaw.2013.09.006 info:eu-repo/semantics/altIdentifier/pmid/24533347 hal-00972560 https://hal.science/hal-00972560 doi:10.1016/j.ijppaw.2013.09.006 PUBMED: 24533347 PUBMEDCENTRAL: PMC3862504 |
op_doi |
https://doi.org/10.1016/j.ijppaw.2013.09.006 |
container_title |
International Journal for Parasitology: Parasites and Wildlife |
container_volume |
2 |
container_start_page |
278 |
op_container_end_page |
285 |
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1790604405306818560 |
spelling |
ftunivreimsca:oai:HAL:hal-00972560v1 2024-02-11T10:06:36+01:00 Environmental determinants of spatial and temporal variations in the transmission of Toxoplasma gondii in its definitive hosts. Afonso, Eve Germain, Estelle Poulle, Marie-Lazarine Ruette, Sandrine Devillard, Sébastien Say, Ludovic Villena, Isabelle Voutquenne-Nazabadioko, Laurence Gilot-Fromont, Emmanuelle Laboratoire Chrono-environnement (UMR 6249) (LCE) Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC) Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC) Centre de Recherche et de Formation en Eco-éthologie (2C2A-CERFE) Université de Reims Champagne-Ardenne (URCA) Office National de la Chasse et de la Faune Sauvage, CNERA Prédateurs Animaux déprédateurs Ecologie et évolution des populations Département écologie évolutive LBBE Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE) Université Claude Bernard Lyon 1 (UCBL) Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL) Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE) Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS) Centre de formation et de recherche en environnement marin (CEFREM) Université de Perpignan Via Domitia (UPVD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS) Biodémographie évolutive 2013-12 https://hal.science/hal-00972560 https://doi.org/10.1016/j.ijppaw.2013.09.006 en eng HAL CCSD Elsevier info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijppaw.2013.09.006 info:eu-repo/semantics/altIdentifier/pmid/24533347 hal-00972560 https://hal.science/hal-00972560 doi:10.1016/j.ijppaw.2013.09.006 PUBMED: 24533347 PUBMEDCENTRAL: PMC3862504 ISSN: 2213-2244 International Journal for Parasitology: Parasites and Wildlife https://hal.science/hal-00972560 International Journal for Parasitology: Parasites and Wildlife, 2013, 2, pp.278-85. ⟨10.1016/j.ijppaw.2013.09.006⟩ [SDV]Life Sciences [q-bio] info:eu-repo/semantics/article Journal articles 2013 ftunivreimsca https://doi.org/10.1016/j.ijppaw.2013.09.006 2024-01-23T23:42:26Z International audience Toxoplasmosis is a major zoonosis, and its prevention requires multiple approaches due to the complex life-cycle of its causative agent, Toxoplasma gondii. Environmental contamination by oocysts is a key factor in the transmission of T. gondii to both humans and meat-producing animals; however, its spatial and temporal variations are poorly understood. We analysed the distribution of T. gondii seropositivity in a sample of 210 cats, including the European wildcat (Felis silvestris silvestris), the domestic cat (Felis silvestris catus) and their hybrids that were collected in Central and Eastern France between 1996 and 2006. We searched for spatial variability among communes and temporal variations among years to relate this variability to landscape and meteorological conditions, which can affect the population dynamics of rodent hosts and the survival of oocysts. The overall seroprevalence was 65.2% (95% CI: 58.6-71.4). As expected, adults were more often infected than young individuals, while the occurrence of infection was not related to cat genotypes. Seroprevalence correlated significantly with farm density and the North-Atlantic Oscillation index, which describes temporal variations of meteorological conditions at the continental scale. The highest seroprevalence values were obtained in areas with high farm densities and during years with cool and moist winters. These results suggest that both farming areas and years with cool and wet winters are associated with increased T. gondii seroprevalence in cats. As cat infection determines the environmental contamination by oocysts, climate and landscape characteristics should be taken into account to improve the risk analysis and prevention of T. gondii. Article in Journal/Newspaper North Atlantic North Atlantic oscillation Université de Reims Champagne-Ardenne: Archives Ouvertes (HAL) International Journal for Parasitology: Parasites and Wildlife 2 278 285 |