West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications
West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe, lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its discovery, WNV has caused multiple human and animal disease outbreaks in all continents, except Antarctica. Inf...
Published in: | Pathogens |
---|---|
Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
MDPI AG
2020
|
Subjects: | |
Online Access: | https://espace.library.uq.edu.au/view/UQ:73d43a3 |
id |
ftunivqespace:oai:espace.library.uq.edu.au:UQ:73d43a3 |
---|---|
record_format |
openpolar |
spelling |
ftunivqespace:oai:espace.library.uq.edu.au:UQ:73d43a3 2023-05-15T13:42:01+02:00 West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications Habarugira, Gervais Suen, Willy W. Hobson-Peters, Jody Hall, Roy A. Bielefeldt-Ohmann, Helle 2020-07-19 https://espace.library.uq.edu.au/view/UQ:73d43a3 eng eng MDPI AG doi:10.3390/pathogens9070589 issn:2076-0817 orcid:0000-0001-5858-0421 orcid:0000-0003-0139-9829 orcid:0000-0001-5778-1387 Not set West Nile virus control one health pathogenesis Journal Article 2020 ftunivqespace https://doi.org/10.3390/pathogens9070589 2020-12-22T15:20:52Z West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe, lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its discovery, WNV has caused multiple human and animal disease outbreaks in all continents, except Antarctica. Infections are associated with economic losses, mainly due to the cost of treatment of infected patients, control programmes, and loss of animals and animal products. The pathogenesis of WNV has been extensively investigated in natural hosts as well as in several animal models, including rodents, lagomorphs, birds, and reptiles. However, most of the proposed pathogenesis hypotheses remain contentious, and much remains to be elucidated. At the same time, the unavailability of specific antiviral treatment or effective and safe vaccines contribute to the perpetuation of the disease and regular occurrence of outbreaks in both endemic and non-endemic areas. Moreover, globalisation and climate change are also important drivers of the emergence and re-emergence of the virus and disease. Here, we give an update of the pathobiology, epidemiology, diagnostics, control, and “One Health” implications of WNV infection and disease. Article in Journal/Newspaper Antarc* Antarctica The University of Queensland: UQ eSpace Pathogens 9 7 589 |
institution |
Open Polar |
collection |
The University of Queensland: UQ eSpace |
op_collection_id |
ftunivqespace |
language |
English |
topic |
West Nile virus control one health pathogenesis |
spellingShingle |
West Nile virus control one health pathogenesis Habarugira, Gervais Suen, Willy W. Hobson-Peters, Jody Hall, Roy A. Bielefeldt-Ohmann, Helle West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications |
topic_facet |
West Nile virus control one health pathogenesis |
description |
West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe, lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its discovery, WNV has caused multiple human and animal disease outbreaks in all continents, except Antarctica. Infections are associated with economic losses, mainly due to the cost of treatment of infected patients, control programmes, and loss of animals and animal products. The pathogenesis of WNV has been extensively investigated in natural hosts as well as in several animal models, including rodents, lagomorphs, birds, and reptiles. However, most of the proposed pathogenesis hypotheses remain contentious, and much remains to be elucidated. At the same time, the unavailability of specific antiviral treatment or effective and safe vaccines contribute to the perpetuation of the disease and regular occurrence of outbreaks in both endemic and non-endemic areas. Moreover, globalisation and climate change are also important drivers of the emergence and re-emergence of the virus and disease. Here, we give an update of the pathobiology, epidemiology, diagnostics, control, and “One Health” implications of WNV infection and disease. |
format |
Article in Journal/Newspaper |
author |
Habarugira, Gervais Suen, Willy W. Hobson-Peters, Jody Hall, Roy A. Bielefeldt-Ohmann, Helle |
author_facet |
Habarugira, Gervais Suen, Willy W. Hobson-Peters, Jody Hall, Roy A. Bielefeldt-Ohmann, Helle |
author_sort |
Habarugira, Gervais |
title |
West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications |
title_short |
West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications |
title_full |
West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications |
title_fullStr |
West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications |
title_full_unstemmed |
West Nile Virus: an update on pathobiology, epidemiology, diagnostics, control and “One Health” implications |
title_sort |
west nile virus: an update on pathobiology, epidemiology, diagnostics, control and “one health” implications |
publisher |
MDPI AG |
publishDate |
2020 |
url |
https://espace.library.uq.edu.au/view/UQ:73d43a3 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
doi:10.3390/pathogens9070589 issn:2076-0817 orcid:0000-0001-5858-0421 orcid:0000-0003-0139-9829 orcid:0000-0001-5778-1387 Not set |
op_doi |
https://doi.org/10.3390/pathogens9070589 |
container_title |
Pathogens |
container_volume |
9 |
container_issue |
7 |
container_start_page |
589 |
_version_ |
1766161842966626304 |