Prenatal exposure to manganese in South African coastal communities
Exposure to environmental sources and altered physiological processes of manganese uptake during pregnancy and its possible effect on prenatal and postnatal development are of concern. This study investigates manganese blood levels at the time of delivery across four cohorts of pregnant women residi...
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Online Access: | http://hdl.handle.net/2263/42104 https://doi.org/10.1039/C4EM00131A |
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ftunivpretoria:oai:repository.up.ac.za:2263/42104 2023-05-15T13:21:37+02:00 Prenatal exposure to manganese in South African coastal communities Rollin, Halina B. Kootbodien, Tahira Theodorou, Penny Odland, Jon Oyvind 2014-09-25T12:44:49Z http://hdl.handle.net/2263/42104 https://doi.org/10.1039/C4EM00131A en eng Royal Society of Chemistry http://hdl.handle.net/2263/42104 Röllin, HB, Kootbodien, T, Theodorou, P & Odland, JO 2014, 'Prenatal exposure to manganese in South African coastal communities', Environmental Science : Processes and Impacts, vol. 16, no. 8, pp. 1903-1912. 2050-7887 (print) doi:10.1039/C4EM00131A © The Royal Society of Chemistry 2014 Manganese Prenatal exposure Diet Water source Lead Postprint Article 2014 ftunivpretoria https://doi.org/10.1039/C4EM00131A 2022-05-31T13:18:18Z Exposure to environmental sources and altered physiological processes of manganese uptake during pregnancy and its possible effect on prenatal and postnatal development are of concern. This study investigates manganese blood levels at the time of delivery across four cohorts of pregnant women residing in coastal communities of South Africa and examines birth outcomes and environmental factors that could influence manganese levels in the study population. The geometric mean (GM) manganese blood levels (MnB) for all women at delivery was 15.2 μg/L. Collectively, rural women reported higher MnB concentrations (GM, 16.1 μg/L) than urban women (GM, 13.5 μg/L, p<0.001). Of the 302 cord blood samples drawn from the study participants (rural women only), GM MnB levels reported for three rural sites were 25.8 μg/L (Rural 1), 33.4 μg/L (Rural 2) and 43.0 μg/L (Rural 3) and were twice as high as their respective maternal levels. However, no significant correlations were found between maternal and cord MnB levels across the 3 study areas. Factors associated with elevated maternal MnB levels, after adjusting for gestational age were: women living in a rural area (Rural 2) (p = 0.021); women drinking potable water from an outdoor/communal tap sourced from municipality (p = 0.021); drinking water from river/stream (p = 0.036); younger maternal age (p = 0.026); consuming leafy vegetables once a week (p = 0.034); and elevated maternal blood lead concentrations (PbB) (p = 0.002). The results indicate that a MnB concentration in rural women during pregnancy is higher compared to urban women and increases with manganese intake from food and water. Research Council of Norway and the National Research Foundation (NRF), South Africa (Grant 64528); the Arctic Monitoring and Assessment Programme (AMAP); and the Royal Norwegian Ministry for Foreign Affairs http://pubs.rsc.org/en/journals/journalissues/em#recentarticles&all 2015-06-30 hb2014 Article in Journal/Newspaper AMAP Arctic University of Pretoria: UPSpace Arctic Norway Environ. Sci.: Processes Impacts 16 8 1903 1912 |
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Open Polar |
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University of Pretoria: UPSpace |
op_collection_id |
ftunivpretoria |
language |
English |
topic |
Manganese Prenatal exposure Diet Water source Lead |
spellingShingle |
Manganese Prenatal exposure Diet Water source Lead Rollin, Halina B. Kootbodien, Tahira Theodorou, Penny Odland, Jon Oyvind Prenatal exposure to manganese in South African coastal communities |
topic_facet |
Manganese Prenatal exposure Diet Water source Lead |
description |
Exposure to environmental sources and altered physiological processes of manganese uptake during pregnancy and its possible effect on prenatal and postnatal development are of concern. This study investigates manganese blood levels at the time of delivery across four cohorts of pregnant women residing in coastal communities of South Africa and examines birth outcomes and environmental factors that could influence manganese levels in the study population. The geometric mean (GM) manganese blood levels (MnB) for all women at delivery was 15.2 μg/L. Collectively, rural women reported higher MnB concentrations (GM, 16.1 μg/L) than urban women (GM, 13.5 μg/L, p<0.001). Of the 302 cord blood samples drawn from the study participants (rural women only), GM MnB levels reported for three rural sites were 25.8 μg/L (Rural 1), 33.4 μg/L (Rural 2) and 43.0 μg/L (Rural 3) and were twice as high as their respective maternal levels. However, no significant correlations were found between maternal and cord MnB levels across the 3 study areas. Factors associated with elevated maternal MnB levels, after adjusting for gestational age were: women living in a rural area (Rural 2) (p = 0.021); women drinking potable water from an outdoor/communal tap sourced from municipality (p = 0.021); drinking water from river/stream (p = 0.036); younger maternal age (p = 0.026); consuming leafy vegetables once a week (p = 0.034); and elevated maternal blood lead concentrations (PbB) (p = 0.002). The results indicate that a MnB concentration in rural women during pregnancy is higher compared to urban women and increases with manganese intake from food and water. Research Council of Norway and the National Research Foundation (NRF), South Africa (Grant 64528); the Arctic Monitoring and Assessment Programme (AMAP); and the Royal Norwegian Ministry for Foreign Affairs http://pubs.rsc.org/en/journals/journalissues/em#recentarticles&all 2015-06-30 hb2014 |
format |
Article in Journal/Newspaper |
author |
Rollin, Halina B. Kootbodien, Tahira Theodorou, Penny Odland, Jon Oyvind |
author_facet |
Rollin, Halina B. Kootbodien, Tahira Theodorou, Penny Odland, Jon Oyvind |
author_sort |
Rollin, Halina B. |
title |
Prenatal exposure to manganese in South African coastal communities |
title_short |
Prenatal exposure to manganese in South African coastal communities |
title_full |
Prenatal exposure to manganese in South African coastal communities |
title_fullStr |
Prenatal exposure to manganese in South African coastal communities |
title_full_unstemmed |
Prenatal exposure to manganese in South African coastal communities |
title_sort |
prenatal exposure to manganese in south african coastal communities |
publisher |
Royal Society of Chemistry |
publishDate |
2014 |
url |
http://hdl.handle.net/2263/42104 https://doi.org/10.1039/C4EM00131A |
geographic |
Arctic Norway |
geographic_facet |
Arctic Norway |
genre |
AMAP Arctic |
genre_facet |
AMAP Arctic |
op_relation |
http://hdl.handle.net/2263/42104 Röllin, HB, Kootbodien, T, Theodorou, P & Odland, JO 2014, 'Prenatal exposure to manganese in South African coastal communities', Environmental Science : Processes and Impacts, vol. 16, no. 8, pp. 1903-1912. 2050-7887 (print) doi:10.1039/C4EM00131A |
op_rights |
© The Royal Society of Chemistry 2014 |
op_doi |
https://doi.org/10.1039/C4EM00131A |
container_title |
Environ. Sci.: Processes Impacts |
container_volume |
16 |
container_issue |
8 |
container_start_page |
1903 |
op_container_end_page |
1912 |
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