Why is Southern African canine babesiosis so virulent? An evolutionary perspective
Canine babesiosis is a common, highly virulent disease in Southern Africa with even pups and juveniles being severely affected. This contrasts with bovine babesiosis, for example, where host, parasite and vector co-evolved and young animals develop immunity after infection without showing clinical s...
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ftunivpretoria:oai:repository.up.ac.za:2263/17187 2023-05-15T15:50:42+02:00 Why is Southern African canine babesiosis so virulent? An evolutionary perspective Penzhorn, Barend Louis 2011 http://hdl.handle.net/2263/17187 https://doi.org/10.1186/1756-3305-4-51 en eng BioMed Central Adobe Acrobat Reader http://hdl.handle.net/2263/17187 Penzhorn, B.L. (2011): Why is Southern African canine babesiosis so virulent? An evolutionary perspective. Parasites & Vectors 2011 4:51. 1756-3305 doi:10.1186/1756-3305-4-51 © 2011 Penzhorn; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY Canine babesiosis Southern Africa Tick-borne diseases in animals Veterinary protozoology -- South Africa Dogs -- Diseases Article 2011 ftunivpretoria https://doi.org/10.1186/1756-3305-4-51 2022-05-31T13:37:03Z Canine babesiosis is a common, highly virulent disease in Southern Africa with even pups and juveniles being severely affected. This contrasts with bovine babesiosis, for example, where host, parasite and vector co-evolved and young animals develop immunity after infection without showing clinical signs. Babesia rossi, the main causative organism of canine babesiosis in sub-Saharan Africa, was first described from a side-striped jackal (Canis adustus) in Kenya. Although data are meagre, there is evidence that indigenous African canids, such as jackals and wild dogs (Lycaon pictus), can harbour the parasite without showing untoward effects. Dogs are not indigenous to Africa. The vast majority of dogs presented at veterinary facilities in South Africa represent recently introduced European, Asian or American breeds. The contention is that B. rossi is a new challenge to which these dogs have not adapted. With intensive treatment of clinical cases, natural selection is effectively negated and the status quo will probably be maintained indefinitely. It is postulated that Babesia vogeli, which frequently results in unapparent infections or mild manifestations in dogs, represents or is closely related to the ancestral form of the canine parasite, possibly originating from wolves (Canis lupus). Publication of the CVBD6 thematic series has been sponsored by Bayer Animal Health GmbH. http://www.parasitesandvectors.com/content/4/1/51 Article in Journal/Newspaper Canis lupus University of Pretoria: UPSpace Parasites & Vectors 4 1 |
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University of Pretoria: UPSpace |
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ftunivpretoria |
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English |
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Canine babesiosis Southern Africa Tick-borne diseases in animals Veterinary protozoology -- South Africa Dogs -- Diseases |
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Canine babesiosis Southern Africa Tick-borne diseases in animals Veterinary protozoology -- South Africa Dogs -- Diseases Penzhorn, Barend Louis Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
topic_facet |
Canine babesiosis Southern Africa Tick-borne diseases in animals Veterinary protozoology -- South Africa Dogs -- Diseases |
description |
Canine babesiosis is a common, highly virulent disease in Southern Africa with even pups and juveniles being severely affected. This contrasts with bovine babesiosis, for example, where host, parasite and vector co-evolved and young animals develop immunity after infection without showing clinical signs. Babesia rossi, the main causative organism of canine babesiosis in sub-Saharan Africa, was first described from a side-striped jackal (Canis adustus) in Kenya. Although data are meagre, there is evidence that indigenous African canids, such as jackals and wild dogs (Lycaon pictus), can harbour the parasite without showing untoward effects. Dogs are not indigenous to Africa. The vast majority of dogs presented at veterinary facilities in South Africa represent recently introduced European, Asian or American breeds. The contention is that B. rossi is a new challenge to which these dogs have not adapted. With intensive treatment of clinical cases, natural selection is effectively negated and the status quo will probably be maintained indefinitely. It is postulated that Babesia vogeli, which frequently results in unapparent infections or mild manifestations in dogs, represents or is closely related to the ancestral form of the canine parasite, possibly originating from wolves (Canis lupus). Publication of the CVBD6 thematic series has been sponsored by Bayer Animal Health GmbH. http://www.parasitesandvectors.com/content/4/1/51 |
format |
Article in Journal/Newspaper |
author |
Penzhorn, Barend Louis |
author_facet |
Penzhorn, Barend Louis |
author_sort |
Penzhorn, Barend Louis |
title |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_short |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_full |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_fullStr |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_full_unstemmed |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_sort |
why is southern african canine babesiosis so virulent? an evolutionary perspective |
publisher |
BioMed Central |
publishDate |
2011 |
url |
http://hdl.handle.net/2263/17187 https://doi.org/10.1186/1756-3305-4-51 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
Adobe Acrobat Reader http://hdl.handle.net/2263/17187 Penzhorn, B.L. (2011): Why is Southern African canine babesiosis so virulent? An evolutionary perspective. Parasites & Vectors 2011 4:51. 1756-3305 doi:10.1186/1756-3305-4-51 |
op_rights |
© 2011 Penzhorn; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1186/1756-3305-4-51 |
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