Retention of fatty acyl desaturase 1 (fads1) in Elopomorpha and Cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in vertebrates 06 Biological Sciences 0604 Genetics 06 Biological Sciences 0601 Biochemistry and Cell Biology 06 Biological Sciences 0603 Evolutionary Biology

• Published in: BMC Evolutionary Biology
• Main Authors: Lopes-Marques M., Kabeya N., Qian Y., Ruivo R., Santos M.M., Venkatesh B., Tocher D.R., Castro L.F.C., Monroig O.
• Other Authors: CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2018
• Subjects: Actinopterygii; Elopomorpha; Lepisosteus oculatus; Lethenteron japonicum; Osteoglossomorpha; Teleostei; Vertebrata; acyl coenzyme A desaturase; unsaturated fatty acid; amino acid sequence; animal; biosynthesis; chemistry; fish; genetics; metabolism; molecular evolution; phylogeny; sequence homology; Animals; Evolution; Molecular; Fatty Acid Desaturases; Fatty Acids; Unsaturated; Fishes; Nucleic Acid; Arctic; Gar’
• Online Access: https://hdl.handle.net/10216/120486; https://doi.org/10.1186/s12862-018-1271-5

Background: Provision of long-chain polyunsaturated fatty acids (LC-PUFA) in vertebrates occurs through the diet or via endogenous production from C18 precursors through consecutive elongations and desaturations. It has been postulated that the abundance of LC-PUFA in the marine environment has rema...