Detection of growth-related QTLs in turbot (Scophtalmus maximux)
Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map in this species has allowed the selection of...
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ftunivpmadrid:oai:oa.upm.es:12732 2023-05-15T18:15:52+02:00 Detection of growth-related QTLs in turbot (Scophtalmus maximux) Sanchez Molano, Enrique Cerna, Alex Toro Ibañez, Miguel Angel Bouza, Carmen Hermida, Miguel Pardo, Belen G. Cabaleiro, Santiago Fernandez, Jesus Martinez, Paulino 2011 application/pdf https://oa.upm.es/12732/ spa spa E.T.S.I. Agrónomos (UPM) http://www.biomedcentral.com/1471-2164/12/473 https://oa.upm.es/12732/ https://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess CC-BY-NC-ND Proceedings of 62th Annual Meeting of the European Association for Animal Production | 62th Annual Meeting of the European Association for Animal Production | 29/08/2011 - 02/09/2011 | Stavanger, Noruega Biología Agricultura info:eu-repo/semantics/conferenceObject Ponencia en Congreso o Jornada PeerReviewed 2011 ftunivpmadrid 2023-03-08T00:15:47Z Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map in this species has allowed the selection of a panel of 100 homogeneously distributed markers covering the 26 linkage groups (LG) suitable for QTL search. In this study we addressed the detection of QTL with effect on body weight, length and Fulton's condition factor. Results Eight families from two genetic breeding programs comprising 814 individuals were used to search for growth related QTL using the panel of microsatellites available for QTL screening. Two different approaches, maximum likelihood and regression interval mapping, were used in order to search for QTL. Up to eleven significant QTL were detected with both methods in at least one family: four for weight on LGs 5, 14, 15 and 16; five for length on LGs 5, 6, 12, 14 and 15; and two for Fulton's condition factor on LGs 3 and 16. In these LGs an association analysis was performed to ascertain the microsatellite marker with the highest apparent effect on the trait, in order to test the possibility of using them for marker assisted selection. Conclusions The use of regression interval mapping and maximum likelihood methods for QTL detection provided consistent results in many cases, although the high variation observed for traits mean among families made it difficult to evaluate QTL effects. Finer mapping of detected QTL, looking for tightly linked markers to the causative mutation, and comparative genomics are suggested to deepen in the analysis of QTL in turbot so they can be applied in marker assisted selection programs. Conference Object Scophthalmus maximus Turbot Archivo Digital UPM (Universidad Politécnica de Madrid) |
institution |
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Archivo Digital UPM (Universidad Politécnica de Madrid) |
op_collection_id |
ftunivpmadrid |
language |
Spanish |
topic |
Biología Agricultura |
spellingShingle |
Biología Agricultura Sanchez Molano, Enrique Cerna, Alex Toro Ibañez, Miguel Angel Bouza, Carmen Hermida, Miguel Pardo, Belen G. Cabaleiro, Santiago Fernandez, Jesus Martinez, Paulino Detection of growth-related QTLs in turbot (Scophtalmus maximux) |
topic_facet |
Biología Agricultura |
description |
Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map in this species has allowed the selection of a panel of 100 homogeneously distributed markers covering the 26 linkage groups (LG) suitable for QTL search. In this study we addressed the detection of QTL with effect on body weight, length and Fulton's condition factor. Results Eight families from two genetic breeding programs comprising 814 individuals were used to search for growth related QTL using the panel of microsatellites available for QTL screening. Two different approaches, maximum likelihood and regression interval mapping, were used in order to search for QTL. Up to eleven significant QTL were detected with both methods in at least one family: four for weight on LGs 5, 14, 15 and 16; five for length on LGs 5, 6, 12, 14 and 15; and two for Fulton's condition factor on LGs 3 and 16. In these LGs an association analysis was performed to ascertain the microsatellite marker with the highest apparent effect on the trait, in order to test the possibility of using them for marker assisted selection. Conclusions The use of regression interval mapping and maximum likelihood methods for QTL detection provided consistent results in many cases, although the high variation observed for traits mean among families made it difficult to evaluate QTL effects. Finer mapping of detected QTL, looking for tightly linked markers to the causative mutation, and comparative genomics are suggested to deepen in the analysis of QTL in turbot so they can be applied in marker assisted selection programs. |
format |
Conference Object |
author |
Sanchez Molano, Enrique Cerna, Alex Toro Ibañez, Miguel Angel Bouza, Carmen Hermida, Miguel Pardo, Belen G. Cabaleiro, Santiago Fernandez, Jesus Martinez, Paulino |
author_facet |
Sanchez Molano, Enrique Cerna, Alex Toro Ibañez, Miguel Angel Bouza, Carmen Hermida, Miguel Pardo, Belen G. Cabaleiro, Santiago Fernandez, Jesus Martinez, Paulino |
author_sort |
Sanchez Molano, Enrique |
title |
Detection of growth-related QTLs in turbot (Scophtalmus maximux) |
title_short |
Detection of growth-related QTLs in turbot (Scophtalmus maximux) |
title_full |
Detection of growth-related QTLs in turbot (Scophtalmus maximux) |
title_fullStr |
Detection of growth-related QTLs in turbot (Scophtalmus maximux) |
title_full_unstemmed |
Detection of growth-related QTLs in turbot (Scophtalmus maximux) |
title_sort |
detection of growth-related qtls in turbot (scophtalmus maximux) |
publisher |
E.T.S.I. Agrónomos (UPM) |
publishDate |
2011 |
url |
https://oa.upm.es/12732/ |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_source |
Proceedings of 62th Annual Meeting of the European Association for Animal Production | 62th Annual Meeting of the European Association for Animal Production | 29/08/2011 - 02/09/2011 | Stavanger, Noruega |
op_relation |
http://www.biomedcentral.com/1471-2164/12/473 https://oa.upm.es/12732/ |
op_rights |
https://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess |
op_rightsnorm |
CC-BY-NC-ND |
_version_ |
1766189105738153984 |