A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns
Seventy-five rats of which at least 45 are males were collected from various localities in Laguna. To determine the durations and concentrations of brodifacoum to be used in the ' experiment, a preliminary study was conducted using 14 ferule rats. For the Lain experiment, 45 male rats were divi...
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1985
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ftunivphilosban:oai:www.ukdr.uplb.edu.ph:etd-undergrad-12065 2024-09-15T18:32:03+00:00 A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns Montana, Rowena Ruth I 1985-05-01T07:00:00Z https://www.ukdr.uplb.edu.ph/etd-undergrad/10987 English eng University Knowledge Digital Repository https://www.ukdr.uplb.edu.ph/etd-undergrad/10987 Undergraduate Theses text 1985 ftunivphilosban 2024-07-21T23:32:10Z Seventy-five rats of which at least 45 are males were collected from various localities in Laguna. To determine the durations and concentrations of brodifacoum to be used in the ' experiment, a preliminary study was conducted using 14 ferule rats. For the Lain experiment, 45 male rats were divided into 3 groups and subjected to 0, 0.001 and 0.0025 percent brodifacoum, respectively. One ml. of t e prepared concentration was given 1,er 100 c of rat of which were fed by gavage. The control was sacrificed 1 day after treatment while the others were sacrificed 1, 4, 7, and 14 days after. Results showed that 0.001 and 0.0025 percent b:-odif.coum failed to inhibit 7itotic activity but not meoitic activity. Chromosomal aberrations such as laggards, unequal separation in anaphase, stickiness, and oblique ana-telophase were induced in somatic cells while no pairing on the some segment was observed in meiotic cells. Differences in chromosome number was also obtained for both treated and untreated rats. The existence of chromosome anomalies in mitotic and meiotic cells suggests that brodifacoum can he possibly used for p:enetic control. Text Rattus rattus University Knowledge Digital Repository UPLB (University of the Philippines Los Baños) |
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University Knowledge Digital Repository UPLB (University of the Philippines Los Baños) |
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Seventy-five rats of which at least 45 are males were collected from various localities in Laguna. To determine the durations and concentrations of brodifacoum to be used in the ' experiment, a preliminary study was conducted using 14 ferule rats. For the Lain experiment, 45 male rats were divided into 3 groups and subjected to 0, 0.001 and 0.0025 percent brodifacoum, respectively. One ml. of t e prepared concentration was given 1,er 100 c of rat of which were fed by gavage. The control was sacrificed 1 day after treatment while the others were sacrificed 1, 4, 7, and 14 days after. Results showed that 0.001 and 0.0025 percent b:-odif.coum failed to inhibit 7itotic activity but not meoitic activity. Chromosomal aberrations such as laggards, unequal separation in anaphase, stickiness, and oblique ana-telophase were induced in somatic cells while no pairing on the some segment was observed in meiotic cells. Differences in chromosome number was also obtained for both treated and untreated rats. The existence of chromosome anomalies in mitotic and meiotic cells suggests that brodifacoum can he possibly used for p:enetic control. |
format |
Text |
author |
Montana, Rowena Ruth I |
spellingShingle |
Montana, Rowena Ruth I A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns |
author_facet |
Montana, Rowena Ruth I |
author_sort |
Montana, Rowena Ruth I |
title |
A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns |
title_short |
A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns |
title_full |
A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns |
title_fullStr |
A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns |
title_full_unstemmed |
A study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on Rattus rattus mindanensis, Mearns |
title_sort |
study on the cytogenetic effect of anticoagulant rodenticide brodifacoum on rattus rattus mindanensis, mearns |
publisher |
University Knowledge Digital Repository |
publishDate |
1985 |
url |
https://www.ukdr.uplb.edu.ph/etd-undergrad/10987 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Undergraduate Theses |
op_relation |
https://www.ukdr.uplb.edu.ph/etd-undergrad/10987 |
_version_ |
1810473802188980224 |