Assessment of the effects of Cu and Ag in oysters Crassostrea gigas (Thunberg, 1793) using a battery of cell and tissue level biomarkers

• Published in: Marine Environmental Research
• Main Authors: Rementeria, A., Mikolaczyk, M., Lanceleur, Laurent, Blanc, G., Soto, M., Schäfer, J., Zaldibar, B.
• Other Authors: Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux (IPREM), Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2016
• Subjects: water quality; Chemical; Shellfish; Silver; procedures; Tissue; Toxicity; water pollutant; metabolism; Metal accumulation; Molluscs; Biomarkers; copper; Crassostrea gigas; Digestive glands; Eco-toxicology; Electric batteries; environmental monitoring; Environmental water; Heavy metals; Integrative biological response; Biomarker; Biological response; Animals; Ostreidae; Physiology; [CHIM]Chemical Sciences
• Online Access: https://hal.science/hal-01495772; https://doi.org/10.1016/j.marenvres.2016.09.002

International audience Oysters are considered sentinel organisms in environmental water quality monitoring programs in which cell and tissue level biomarkers are reliable tools. Copper (Cu) and silver (Ag) are present in relatively high concentrations in several estuaries, potentially affecting environmental and human health. Crassostrea gigas oysters were exposed during 28 days to a range of environmentally relevant concentrations of Cu and Ag alone or in mixture. Effects were studied through cell and tissue level biomarkers approach. Results indicated: changes in the Condition Index (CI), altered digestive gland epithelium and presence of histopathological alterations in the gonad and digestive gland of exposed oysters. A time-dependent increase in lipofuscin contents in exposed oysters and an increase in intralysosomal metal accumulation in digestive cells through the experiment were also recorded. The Integrative Biological Response (IBR) Index showed that even at low exposure levels, Ag and Cu can produce alterations on oysters’ health status. © 2016 Elsevier Ltd