Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni
Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in...
Published in: | International Journal of Molecular Sciences |
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Online Access: | https://hdl.handle.net/11577/3463062 https://doi.org/10.3390/ijms232112799 |
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ftunivpadovairis:oai:www.research.unipd.it:11577/3463062 2024-04-14T08:01:12+00:00 Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni Bakiu R. Pacchini S. Piva E. Schumann S. Tolomeo A. M. Ferro D. Irato P. Santovito G. Bakiu, R. Pacchini, S. Piva, E. Schumann, S. Tolomeo, A. M. Ferro, D. Irato, P. Santovito, G. 2022 STAMPA https://hdl.handle.net/11577/3463062 https://doi.org/10.3390/ijms232112799 eng eng MDPI info:eu-repo/semantics/altIdentifier/pmid/36361591 info:eu-repo/semantics/altIdentifier/wos/WOS:000882165700001 volume:23 issue:21 firstpage:12799 journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES https://hdl.handle.net/11577/3463062 doi:10.3390/ijms232112799 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85141628139 info:eu-repo/semantics/openAccess Antarctica antioxidant cadmium copper fish metallothioneins info:eu-repo/semantics/article 2022 ftunivpadovairis https://doi.org/10.3390/ijms232112799 2024-03-21T18:40:54Z Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in its tissues. Specimens of this Antarctic fish were collected from Terra Nova Bay (Ross Sea) and used for a metal exposure experiment in controlled laboratory conditions. The two treatments led to a significant accumulation of both metals and increased gene transcription only for the MT-1. The biosynthesis of MTs was verified especially in specimens exposed to Cd, but most of these proteins were soon oxidized, probably because they were involved in cell protection against oxidative stress risk by scavenging reactive oxygen species. The obtained data highlighted the phenotypic plasticity of T. hansoni, a species that evolved in an environment characterized by naturally high concentrations of Cu and Cd, and maybe the possibility for the Antarctic fish to face the challenges of a world that is becoming more toxic every day. Article in Journal/Newspaper Antarc* Antarctic Antarctica Ross Sea Padua Research Archive (IRIS - Università degli Studi di Padova) Antarctic The Antarctic Ross Sea Terra Nova Bay International Journal of Molecular Sciences 23 21 12799 |
institution |
Open Polar |
collection |
Padua Research Archive (IRIS - Università degli Studi di Padova) |
op_collection_id |
ftunivpadovairis |
language |
English |
topic |
Antarctica antioxidant cadmium copper fish metallothioneins |
spellingShingle |
Antarctica antioxidant cadmium copper fish metallothioneins Bakiu R. Pacchini S. Piva E. Schumann S. Tolomeo A. M. Ferro D. Irato P. Santovito G. Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
topic_facet |
Antarctica antioxidant cadmium copper fish metallothioneins |
description |
Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in its tissues. Specimens of this Antarctic fish were collected from Terra Nova Bay (Ross Sea) and used for a metal exposure experiment in controlled laboratory conditions. The two treatments led to a significant accumulation of both metals and increased gene transcription only for the MT-1. The biosynthesis of MTs was verified especially in specimens exposed to Cd, but most of these proteins were soon oxidized, probably because they were involved in cell protection against oxidative stress risk by scavenging reactive oxygen species. The obtained data highlighted the phenotypic plasticity of T. hansoni, a species that evolved in an environment characterized by naturally high concentrations of Cu and Cd, and maybe the possibility for the Antarctic fish to face the challenges of a world that is becoming more toxic every day. |
author2 |
Bakiu, R. Pacchini, S. Piva, E. Schumann, S. Tolomeo, A. M. Ferro, D. Irato, P. Santovito, G. |
format |
Article in Journal/Newspaper |
author |
Bakiu R. Pacchini S. Piva E. Schumann S. Tolomeo A. M. Ferro D. Irato P. Santovito G. |
author_facet |
Bakiu R. Pacchini S. Piva E. Schumann S. Tolomeo A. M. Ferro D. Irato P. Santovito G. |
author_sort |
Bakiu R. |
title |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_short |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_full |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_fullStr |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_full_unstemmed |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_sort |
metallothionein expression as a physiological response against metal toxicity in the striped rockcod trematomus hansoni |
publisher |
MDPI |
publishDate |
2022 |
url |
https://hdl.handle.net/11577/3463062 https://doi.org/10.3390/ijms232112799 |
geographic |
Antarctic The Antarctic Ross Sea Terra Nova Bay |
geographic_facet |
Antarctic The Antarctic Ross Sea Terra Nova Bay |
genre |
Antarc* Antarctic Antarctica Ross Sea |
genre_facet |
Antarc* Antarctic Antarctica Ross Sea |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/36361591 info:eu-repo/semantics/altIdentifier/wos/WOS:000882165700001 volume:23 issue:21 firstpage:12799 journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES https://hdl.handle.net/11577/3463062 doi:10.3390/ijms232112799 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85141628139 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.3390/ijms232112799 |
container_title |
International Journal of Molecular Sciences |
container_volume |
23 |
container_issue |
21 |
container_start_page |
12799 |
_version_ |
1796307936247545856 |