Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings
Morbilliviruses are recognized as biological agents highly impacting the health and conservation status of free-ranging cetaceans worldwide, as clearly exemplified by the two Dolphin Morbillivirus (DMV) epidemics of 1990-1992 and 2006-2008 among Mediterranean striped dolphins (Stenella coeruleoalba)...
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Online Access: | http://hdl.handle.net/11577/2525190 https://doi.org/10.1016/j.rvsc.2012.07.030 |
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ftunivpadovairis:oai:www.research.unipd.it:11577/2525190 2024-04-21T07:57:53+00:00 Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings Giovanni Di Guardo Cristina Esmeralda Di Francesco Claudia Eleni Cristiano Cocumelli Francesco Scholl Cristina Casalone Simone Peletto Walter Mignone Cristiana Tittarelli Fabio Di Nocera Leonardo Leonardi Antonio Fernández MARCER, FEDERICA MAZZARIOL, SANDRO Giovanni Di, Guardo Cristina Esmeralda Di, Francesco Claudia, Eleni Cristiano, Cocumelli Francesco, Scholl Cristina, Casalone Simone, Peletto Walter, Mignone Cristiana, Tittarelli Fabio Di, Nocera Leonardo, Leonardi Antonio, Fernández Marcer, Federica Mazzariol, Sandro 2013 STAMPA http://hdl.handle.net/11577/2525190 https://doi.org/10.1016/j.rvsc.2012.07.030 eng eng info:eu-repo/semantics/altIdentifier/pmid/22921372 info:eu-repo/semantics/altIdentifier/wos/WOS:000319028000021 journal:RESEARCH IN VETERINARY SCIENCE http://hdl.handle.net/11577/2525190 doi:10.1016/j.rvsc.2012.07.030 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84871511713 Morbilliviru Mediterranean Sea dolphins info:eu-repo/semantics/article 2013 ftunivpadovairis https://doi.org/10.1016/j.rvsc.2012.07.030 2024-03-28T01:53:24Z Morbilliviruses are recognized as biological agents highly impacting the health and conservation status of free-ranging cetaceans worldwide, as clearly exemplified by the two Dolphin Morbillivirus (DMV) epidemics of 1990-1992 and 2006-2008 among Mediterranean striped dolphins (Stenella coeruleoalba). After these two epidemics, morbilliviral infection (MI) cases with peculiar neurobiological features were reported in striped dolphins stranded along the Spanish coastline. Affected cetaceans showed a subacute-to-chronic, non-suppurative encephalitis, with brain lesions strongly resembling those found in human "subacute sclerosing panencephalitis" and "old dog encephalitis". Brain was the only tissue in which morbilliviral antigen and/or genome could be detected. Beside a case of morbilliviral encephalitis in a striped dolphin's calf stranded in 2009, we observed 5 additional MI cases in 2 striped dolphins, 1 bottlenose dolphin (Tursiops truncatus) and 2 fin whales (Balaenoptera physalus), all stranded in 2011 along the Italian coastline. Noteworthy, 3 of these animals (2 striped dolphins and 1 bottlenose dolphin) showed immunohistochemical (IHC) and/or biomolecular (PCR) evidence of morbilliviral antigen and/or genome exclusively in their brain, with 1 striped dolphin and 1 bottlenose dolphin also exhibiting a non-suppurative encephalitis. Furthermore, simultaneous IHC and PCR evidence of a Toxoplasma gondii coinfection was obtained in 1 fin whale. The above results are consistent with those reported in striped dolphins after the two MI epidemics of 1990-92 and 2006-2008, with evidence of morbilliviral antigen and/or genome being found exclusively in the brain tissue from affected animals. Article in Journal/Newspaper Balaenoptera physalus Fin whale Padua Research Archive (IRIS - Università degli Studi di Padova) Research in Veterinary Science 94 1 132 137 |
institution |
Open Polar |
collection |
Padua Research Archive (IRIS - Università degli Studi di Padova) |
op_collection_id |
ftunivpadovairis |
language |
English |
topic |
Morbilliviru Mediterranean Sea dolphins |
spellingShingle |
Morbilliviru Mediterranean Sea dolphins Giovanni Di Guardo Cristina Esmeralda Di Francesco Claudia Eleni Cristiano Cocumelli Francesco Scholl Cristina Casalone Simone Peletto Walter Mignone Cristiana Tittarelli Fabio Di Nocera Leonardo Leonardi Antonio Fernández MARCER, FEDERICA MAZZARIOL, SANDRO Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings |
topic_facet |
Morbilliviru Mediterranean Sea dolphins |
description |
Morbilliviruses are recognized as biological agents highly impacting the health and conservation status of free-ranging cetaceans worldwide, as clearly exemplified by the two Dolphin Morbillivirus (DMV) epidemics of 1990-1992 and 2006-2008 among Mediterranean striped dolphins (Stenella coeruleoalba). After these two epidemics, morbilliviral infection (MI) cases with peculiar neurobiological features were reported in striped dolphins stranded along the Spanish coastline. Affected cetaceans showed a subacute-to-chronic, non-suppurative encephalitis, with brain lesions strongly resembling those found in human "subacute sclerosing panencephalitis" and "old dog encephalitis". Brain was the only tissue in which morbilliviral antigen and/or genome could be detected. Beside a case of morbilliviral encephalitis in a striped dolphin's calf stranded in 2009, we observed 5 additional MI cases in 2 striped dolphins, 1 bottlenose dolphin (Tursiops truncatus) and 2 fin whales (Balaenoptera physalus), all stranded in 2011 along the Italian coastline. Noteworthy, 3 of these animals (2 striped dolphins and 1 bottlenose dolphin) showed immunohistochemical (IHC) and/or biomolecular (PCR) evidence of morbilliviral antigen and/or genome exclusively in their brain, with 1 striped dolphin and 1 bottlenose dolphin also exhibiting a non-suppurative encephalitis. Furthermore, simultaneous IHC and PCR evidence of a Toxoplasma gondii coinfection was obtained in 1 fin whale. The above results are consistent with those reported in striped dolphins after the two MI epidemics of 1990-92 and 2006-2008, with evidence of morbilliviral antigen and/or genome being found exclusively in the brain tissue from affected animals. |
author2 |
Giovanni Di, Guardo Cristina Esmeralda Di, Francesco Claudia, Eleni Cristiano, Cocumelli Francesco, Scholl Cristina, Casalone Simone, Peletto Walter, Mignone Cristiana, Tittarelli Fabio Di, Nocera Leonardo, Leonardi Antonio, Fernández Marcer, Federica Mazzariol, Sandro |
format |
Article in Journal/Newspaper |
author |
Giovanni Di Guardo Cristina Esmeralda Di Francesco Claudia Eleni Cristiano Cocumelli Francesco Scholl Cristina Casalone Simone Peletto Walter Mignone Cristiana Tittarelli Fabio Di Nocera Leonardo Leonardi Antonio Fernández MARCER, FEDERICA MAZZARIOL, SANDRO |
author_facet |
Giovanni Di Guardo Cristina Esmeralda Di Francesco Claudia Eleni Cristiano Cocumelli Francesco Scholl Cristina Casalone Simone Peletto Walter Mignone Cristiana Tittarelli Fabio Di Nocera Leonardo Leonardi Antonio Fernández MARCER, FEDERICA MAZZARIOL, SANDRO |
author_sort |
Giovanni Di Guardo |
title |
Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings |
title_short |
Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings |
title_full |
Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings |
title_fullStr |
Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings |
title_full_unstemmed |
Morbillivirus infection in cetaceans stranded along the Italian coastline: Pathological, immunohistochemical and biomolecular findings |
title_sort |
morbillivirus infection in cetaceans stranded along the italian coastline: pathological, immunohistochemical and biomolecular findings |
publishDate |
2013 |
url |
http://hdl.handle.net/11577/2525190 https://doi.org/10.1016/j.rvsc.2012.07.030 |
genre |
Balaenoptera physalus Fin whale |
genre_facet |
Balaenoptera physalus Fin whale |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/22921372 info:eu-repo/semantics/altIdentifier/wos/WOS:000319028000021 journal:RESEARCH IN VETERINARY SCIENCE http://hdl.handle.net/11577/2525190 doi:10.1016/j.rvsc.2012.07.030 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84871511713 |
op_doi |
https://doi.org/10.1016/j.rvsc.2012.07.030 |
container_title |
Research in Veterinary Science |
container_volume |
94 |
container_issue |
1 |
container_start_page |
132 |
op_container_end_page |
137 |
_version_ |
1796939315163430912 |