Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images
Abstract. Lower back pain (LBP) is a common physiological condition that affects 50–80% of the adult population at some point in their lives. For example, the economic load of LBP in Sweden was estimated to be approx. at C740 million in 2011. In LBP diagnostics, magnetic resonance imaging (MRI) is o...
Main Author: | |
---|---|
Format: | Master Thesis |
Language: | English |
Published: |
University of Oulu
2023
|
Subjects: | |
Online Access: | http://jultika.oulu.fi/Record/nbnfioulu-202302141142 |
id |
ftunivoulu:oai:oulu.fi:nbnfioulu-202302141142 |
---|---|
record_format |
openpolar |
spelling |
ftunivoulu:oai:oulu.fi:nbnfioulu-202302141142 2023-07-30T04:05:50+02:00 Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images Al-Rubaye, M. (Mustafa) 2023-02-14 application/pdf http://jultika.oulu.fi/Record/nbnfioulu-202302141142 eng eng University of Oulu info:eu-repo/semantics/openAccess © Mustafa Al-Rubaye, 2023. Except otherwise noted, the reuse of this document is authorised under a Creative Commons Attribution 4.0 International (CC-BY 4.0) licence (https://creativecommons.org/licenses/by/4.0/). This means that reuse is allowed provided appropriate credit is given and any changes are indicated. For any use or reproduction of elements that are not owned by the author(s), permission may need to be directly from the respective right holders. Lääketieteen tekniikka (tietotekniikka) info:eu-repo/semantics/masterThesis info:eu-repo/semantics/publishedVersion 2023 ftunivoulu 2023-07-08T20:01:01Z Abstract. Lower back pain (LBP) is a common physiological condition that affects 50–80% of the adult population at some point in their lives. For example, the economic load of LBP in Sweden was estimated to be approx. at C740 million in 2011. In LBP diagnostics, magnetic resonance imaging (MRI) is often used. MRI is used to visualize the structures in the lumbar region of the spine such as disks, bones, and spaces between the vertebral bones where nerves pass through. The lumbar spine refers to the lowest five vertebrae and intervertebral discs of the spine. MRI provides a detailed picture of the lumbar spine to get visual confirmation of any abnormalities potentially related to LBP to support the diagnosis process. The goal of this thesis was to investigate visual patterns related to LBP in T2-weighted MR images measured with a fast spin-echo sequence on a GE Healthcare Signa HDxt 1.5 T MRI system. A convolutional neural network was used to classify MRIs into symptomatic and asymptomatic cases and to develop a fully automated pain prediction process. A total of 526 MRI examinations with supporting pain questionnaires from the Northern Finland Birth Cohort 1966 (NFBC1966) were used. Three different datasets were created for the experiments: i) a dataset with mid-sagittal slices from the center of the spine from each examination, ii) a dataset with mid-sagittal slices and its immediate neighboring slices, and similarly, iii) a dataset with five middle-most sagittal slices. In each dataset, individual slices were considered as independent samples, i.e., inputs for the classification method. The developed classification method yielded the best results when the input dataset comprised of three middle-most slices (Balanced Accuracy score (BACC) of 0.709 ± 0.011, Average Precision (AP) of 0.467 ± 0.025, and Area Under Receiver Operating Characteristic curve (ROC-AUC) of 0.740 ± 0.008). The baseline model trained using only the mid-sagittal slice for classification yielded the lowest classification scores (BACC of ... Master Thesis Northern Finland Jultika - University of Oulu repository |
institution |
Open Polar |
collection |
Jultika - University of Oulu repository |
op_collection_id |
ftunivoulu |
language |
English |
topic |
Lääketieteen tekniikka (tietotekniikka) |
spellingShingle |
Lääketieteen tekniikka (tietotekniikka) Al-Rubaye, M. (Mustafa) Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images |
topic_facet |
Lääketieteen tekniikka (tietotekniikka) |
description |
Abstract. Lower back pain (LBP) is a common physiological condition that affects 50–80% of the adult population at some point in their lives. For example, the economic load of LBP in Sweden was estimated to be approx. at C740 million in 2011. In LBP diagnostics, magnetic resonance imaging (MRI) is often used. MRI is used to visualize the structures in the lumbar region of the spine such as disks, bones, and spaces between the vertebral bones where nerves pass through. The lumbar spine refers to the lowest five vertebrae and intervertebral discs of the spine. MRI provides a detailed picture of the lumbar spine to get visual confirmation of any abnormalities potentially related to LBP to support the diagnosis process. The goal of this thesis was to investigate visual patterns related to LBP in T2-weighted MR images measured with a fast spin-echo sequence on a GE Healthcare Signa HDxt 1.5 T MRI system. A convolutional neural network was used to classify MRIs into symptomatic and asymptomatic cases and to develop a fully automated pain prediction process. A total of 526 MRI examinations with supporting pain questionnaires from the Northern Finland Birth Cohort 1966 (NFBC1966) were used. Three different datasets were created for the experiments: i) a dataset with mid-sagittal slices from the center of the spine from each examination, ii) a dataset with mid-sagittal slices and its immediate neighboring slices, and similarly, iii) a dataset with five middle-most sagittal slices. In each dataset, individual slices were considered as independent samples, i.e., inputs for the classification method. The developed classification method yielded the best results when the input dataset comprised of three middle-most slices (Balanced Accuracy score (BACC) of 0.709 ± 0.011, Average Precision (AP) of 0.467 ± 0.025, and Area Under Receiver Operating Characteristic curve (ROC-AUC) of 0.740 ± 0.008). The baseline model trained using only the mid-sagittal slice for classification yielded the lowest classification scores (BACC of ... |
format |
Master Thesis |
author |
Al-Rubaye, M. (Mustafa) |
author_facet |
Al-Rubaye, M. (Mustafa) |
author_sort |
Al-Rubaye, M. (Mustafa) |
title |
Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images |
title_short |
Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images |
title_full |
Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images |
title_fullStr |
Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images |
title_full_unstemmed |
Deep learning-based lower back pain classification and detection from T2-weighted magnetic resonance images |
title_sort |
deep learning-based lower back pain classification and detection from t2-weighted magnetic resonance images |
publisher |
University of Oulu |
publishDate |
2023 |
url |
http://jultika.oulu.fi/Record/nbnfioulu-202302141142 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_rights |
info:eu-repo/semantics/openAccess © Mustafa Al-Rubaye, 2023. Except otherwise noted, the reuse of this document is authorised under a Creative Commons Attribution 4.0 International (CC-BY 4.0) licence (https://creativecommons.org/licenses/by/4.0/). This means that reuse is allowed provided appropriate credit is given and any changes are indicated. For any use or reproduction of elements that are not owned by the author(s), permission may need to be directly from the respective right holders. |
_version_ |
1772818085329240064 |