Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study
Abstract Psychiatric illnesses can affect the social transitions of adolescence and young adulthood, such as completing education and entering working life and relationships. However, associations between earlier onset age and long-term outcomes among those with early-onset psychoses (EOP) are uncle...
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ftunivoulu:oai:oulu.fi:nbnfi-fe2023081898137 2023-09-05T13:21:55+02:00 Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study Majuri, T. (Tuomas) Haapea, M. (Marianne) Nordström, T. (Tanja) Säynäjäkangas, V. (Veera) Moilanen, K. (Kristiina) Tolonen, J. (Jonna) Ala-Mursula, L. (Leena) Miettunen, J. (Jouko) Jääskeläinen, E. (Erika) 2023 application/pdf http://urn.fi/urn:nbn:fi-fe2023081898137 eng eng Springer Nature info:eu-repo/semantics/openAccess © The Author(s) 2023. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. https://creativecommons.org/licenses/by/4.0/ Early-onset Follow-up Onset age Outcome Psychosis Schizophrenia info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2023 ftunivoulu 2023-08-23T22:59:35Z Abstract Psychiatric illnesses can affect the social transitions of adolescence and young adulthood, such as completing education and entering working life and relationships. However, associations between earlier onset age and long-term outcomes among those with early-onset psychoses (EOP) are unclear, as are the long-term outcomes of EOP compared to non-psychotic disorders. We used national register data of the Northern Finland Birth Cohort 1986 to detect persons with EOP and other early-onset psychiatric disorders. The long-term clinical and work-family outcomes of persons with onset age before 18 years (n = 41 psychoses, n = 495 non-psychoses) or between 18–22 years (n = 61 psychoses, n = 377 non-psychoses) were compared. Individuals with the onset of psychosis between 18–22 years had significantly more unfavourable long-term outcomes when compared to those with psychosis onset before 18 years. Persons with psychosis onset before the age of 18 years had similar outcomes to those with non-psychotic psychiatric disorder onset before 18 years regarding educational level, marital status, having children, and substance use disorders. Individuals with EOP were more often on a disability pension compared to those with other early-onset mental disorders. Adjusting for sex, educational level and substance use only slightly diluted these results. Unexpectedly, later onset age of EOP was associated with worse outcomes. Those with psychosis onset between 18–22 years of age are in a critical period, which underlines the importance of investing on interventions in this age group. Further studies on the effect of the onset age on later outcomes in EOP are needed. Article in Journal/Newspaper Northern Finland Jultika - University of Oulu repository |
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Open Polar |
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Jultika - University of Oulu repository |
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ftunivoulu |
language |
English |
topic |
Early-onset Follow-up Onset age Outcome Psychosis Schizophrenia |
spellingShingle |
Early-onset Follow-up Onset age Outcome Psychosis Schizophrenia Majuri, T. (Tuomas) Haapea, M. (Marianne) Nordström, T. (Tanja) Säynäjäkangas, V. (Veera) Moilanen, K. (Kristiina) Tolonen, J. (Jonna) Ala-Mursula, L. (Leena) Miettunen, J. (Jouko) Jääskeläinen, E. (Erika) Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study |
topic_facet |
Early-onset Follow-up Onset age Outcome Psychosis Schizophrenia |
description |
Abstract Psychiatric illnesses can affect the social transitions of adolescence and young adulthood, such as completing education and entering working life and relationships. However, associations between earlier onset age and long-term outcomes among those with early-onset psychoses (EOP) are unclear, as are the long-term outcomes of EOP compared to non-psychotic disorders. We used national register data of the Northern Finland Birth Cohort 1986 to detect persons with EOP and other early-onset psychiatric disorders. The long-term clinical and work-family outcomes of persons with onset age before 18 years (n = 41 psychoses, n = 495 non-psychoses) or between 18–22 years (n = 61 psychoses, n = 377 non-psychoses) were compared. Individuals with the onset of psychosis between 18–22 years had significantly more unfavourable long-term outcomes when compared to those with psychosis onset before 18 years. Persons with psychosis onset before the age of 18 years had similar outcomes to those with non-psychotic psychiatric disorder onset before 18 years regarding educational level, marital status, having children, and substance use disorders. Individuals with EOP were more often on a disability pension compared to those with other early-onset mental disorders. Adjusting for sex, educational level and substance use only slightly diluted these results. Unexpectedly, later onset age of EOP was associated with worse outcomes. Those with psychosis onset between 18–22 years of age are in a critical period, which underlines the importance of investing on interventions in this age group. Further studies on the effect of the onset age on later outcomes in EOP are needed. |
format |
Article in Journal/Newspaper |
author |
Majuri, T. (Tuomas) Haapea, M. (Marianne) Nordström, T. (Tanja) Säynäjäkangas, V. (Veera) Moilanen, K. (Kristiina) Tolonen, J. (Jonna) Ala-Mursula, L. (Leena) Miettunen, J. (Jouko) Jääskeläinen, E. (Erika) |
author_facet |
Majuri, T. (Tuomas) Haapea, M. (Marianne) Nordström, T. (Tanja) Säynäjäkangas, V. (Veera) Moilanen, K. (Kristiina) Tolonen, J. (Jonna) Ala-Mursula, L. (Leena) Miettunen, J. (Jouko) Jääskeläinen, E. (Erika) |
author_sort |
Majuri, T. (Tuomas) |
title |
Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study |
title_short |
Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study |
title_full |
Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study |
title_fullStr |
Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study |
title_full_unstemmed |
Effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based Northern Finland Birth Cohort 1986 study |
title_sort |
effect of onset age on the long-term outcome of early-onset psychoses and other mental disorders:a register-based northern finland birth cohort 1986 study |
publisher |
Springer Nature |
publishDate |
2023 |
url |
http://urn.fi/urn:nbn:fi-fe2023081898137 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_rights |
info:eu-repo/semantics/openAccess © The Author(s) 2023. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. https://creativecommons.org/licenses/by/4.0/ |
_version_ |
1776202480736010240 |