Sudden cardiac death after alcohol intake:classification and autopsy findings
Abstract Alcohol is known to have an immediate effect on cardiac rhythm, and previous studies have found that a notable proportion of sudden cardiac deaths (SCD) occur after alcohol intake. The objective of the present study was to investigate the association between the timing of alcohol intake and...
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ftunivoulu:oai:oulu.fi:nbnfi-fe2023021427206 2023-07-30T04:05:49+02:00 Sudden cardiac death after alcohol intake:classification and autopsy findings Holmström, L. (Lauri) Kauppila, J. (Janna) Vähätalo, J. (Juha) Pakanen, L. (Lasse) Perkiömäki, J. (Juha) Huikuri, H. (Heikki) Junttila, J. (Juhani) 2022 application/pdf http://urn.fi/urn:nbn:fi-fe2023021427206 eng eng Springer Nature info:eu-repo/semantics/openAccess © The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. https://creativecommons.org/licenses/by/4.0/ Cardiology Medical research info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2022 ftunivoulu 2023-07-08T20:01:01Z Abstract Alcohol is known to have an immediate effect on cardiac rhythm, and previous studies have found that a notable proportion of sudden cardiac deaths (SCD) occur after alcohol intake. The objective of the present study was to investigate the association between the timing of alcohol intake and SCD. Our study population is drawn from the Fingesture study, which includes 5869 consecutive SCD cases from Northern Finland who underwent medicolegal autopsy 1998–2017. Toxicological analysis was performed if there was any suspicion of toxic exposure, or if there was no obvious immediate cause of SCD at autopsy. We found that 1563 (27%) of all SCD victims had alcohol in blood or urine at autopsy (mean age (61 ± 10 years, 88% male). Eighty-six percent of alcohol-related SCD victims had higher urine alcohol concentration than blood alcohol concentration, referring to the late-stage inebriation. These results suggest that the majority of alcohol-related SCDs occur at the late stage of inebriation. Article in Journal/Newspaper Northern Finland Jultika - University of Oulu repository |
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Jultika - University of Oulu repository |
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English |
topic |
Cardiology Medical research |
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Cardiology Medical research Holmström, L. (Lauri) Kauppila, J. (Janna) Vähätalo, J. (Juha) Pakanen, L. (Lasse) Perkiömäki, J. (Juha) Huikuri, H. (Heikki) Junttila, J. (Juhani) Sudden cardiac death after alcohol intake:classification and autopsy findings |
topic_facet |
Cardiology Medical research |
description |
Abstract Alcohol is known to have an immediate effect on cardiac rhythm, and previous studies have found that a notable proportion of sudden cardiac deaths (SCD) occur after alcohol intake. The objective of the present study was to investigate the association between the timing of alcohol intake and SCD. Our study population is drawn from the Fingesture study, which includes 5869 consecutive SCD cases from Northern Finland who underwent medicolegal autopsy 1998–2017. Toxicological analysis was performed if there was any suspicion of toxic exposure, or if there was no obvious immediate cause of SCD at autopsy. We found that 1563 (27%) of all SCD victims had alcohol in blood or urine at autopsy (mean age (61 ± 10 years, 88% male). Eighty-six percent of alcohol-related SCD victims had higher urine alcohol concentration than blood alcohol concentration, referring to the late-stage inebriation. These results suggest that the majority of alcohol-related SCDs occur at the late stage of inebriation. |
format |
Article in Journal/Newspaper |
author |
Holmström, L. (Lauri) Kauppila, J. (Janna) Vähätalo, J. (Juha) Pakanen, L. (Lasse) Perkiömäki, J. (Juha) Huikuri, H. (Heikki) Junttila, J. (Juhani) |
author_facet |
Holmström, L. (Lauri) Kauppila, J. (Janna) Vähätalo, J. (Juha) Pakanen, L. (Lasse) Perkiömäki, J. (Juha) Huikuri, H. (Heikki) Junttila, J. (Juhani) |
author_sort |
Holmström, L. (Lauri) |
title |
Sudden cardiac death after alcohol intake:classification and autopsy findings |
title_short |
Sudden cardiac death after alcohol intake:classification and autopsy findings |
title_full |
Sudden cardiac death after alcohol intake:classification and autopsy findings |
title_fullStr |
Sudden cardiac death after alcohol intake:classification and autopsy findings |
title_full_unstemmed |
Sudden cardiac death after alcohol intake:classification and autopsy findings |
title_sort |
sudden cardiac death after alcohol intake:classification and autopsy findings |
publisher |
Springer Nature |
publishDate |
2022 |
url |
http://urn.fi/urn:nbn:fi-fe2023021427206 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_rights |
info:eu-repo/semantics/openAccess © The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. https://creativecommons.org/licenses/by/4.0/ |
_version_ |
1772818018681749504 |