Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death
Abstract Introduction: Non-ischaemic heart disease (NIHD) is the underlying pathology in∼20% of all sudden cardiac deaths (SCDs). Heavy drinking is known to be associated with SCD due to ischaemic heart disease, but studies on association of recent alcohol consumption and SCD in patients with NIHD a...
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ftunivoulu:oai:oulu.fi:nbnfi-fe2021042211424 2023-07-30T04:05:49+02:00 Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death Kauppila, J. P. (Janna P.) Pakanen, L. (Lasse) Porvari, K. (Katja) Vähätalo, J. (Juha) Holmström, L. (Lauri) Perkiömäki, J. S. (Juha S.) Huikuri, H. V. (Heikki V.) Junttila, M. J. (M. Juhani) 2021 application/pdf http://urn.fi/urn:nbn:fi-fe2021042211424 eng eng Informa info:eu-repo/semantics/openAccess © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/ alcohol medico-legal autopsy non-ischaemic heart disease sudden cardiac death info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2021 ftunivoulu 2023-07-08T19:57:50Z Abstract Introduction: Non-ischaemic heart disease (NIHD) is the underlying pathology in∼20% of all sudden cardiac deaths (SCDs). Heavy drinking is known to be associated with SCD due to ischaemic heart disease, but studies on association of recent alcohol consumption and SCD in patients with NIHD are scarce. We evaluated the blood alcohol levels of autopsy verified non-ischaemic SCD victims. Methods: Study population was derived from the Finnish Genetic Study of Arrhythmic Events (Fingesture) (n = 5869, mean age 65 ± 12, 79% males). All deaths occurred in Northern Finland during 1998–2017. All victims underwent a medico-legal autopsy. Subjects of SCD due to ischaemic heart disease were excluded. Results: A total of 1301 (mean age 57 ± 12, 78% males) victims of SCD due to NIHD were included in the study. The blood ethanol level was elevated in 543 (42%) subjects, out of which the blood alcohol level was ≥0.10%in 339 (62%) subjects and ≥0.15%in 252 (46%) subjects. Male SCD victims had alcohol in blood more frequently compared to females (45% versus 31%, p < .001). Conclusion: Elevated blood alcohol level is common in SCD victims due to NIHD, especially in males. Recent alcohol consumption might contribute to the subsequent SCD in many non-ischaemic SCD victims. Article in Journal/Newspaper Northern Finland Jultika - University of Oulu repository |
institution |
Open Polar |
collection |
Jultika - University of Oulu repository |
op_collection_id |
ftunivoulu |
language |
English |
topic |
alcohol medico-legal autopsy non-ischaemic heart disease sudden cardiac death |
spellingShingle |
alcohol medico-legal autopsy non-ischaemic heart disease sudden cardiac death Kauppila, J. P. (Janna P.) Pakanen, L. (Lasse) Porvari, K. (Katja) Vähätalo, J. (Juha) Holmström, L. (Lauri) Perkiömäki, J. S. (Juha S.) Huikuri, H. V. (Heikki V.) Junttila, M. J. (M. Juhani) Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death |
topic_facet |
alcohol medico-legal autopsy non-ischaemic heart disease sudden cardiac death |
description |
Abstract Introduction: Non-ischaemic heart disease (NIHD) is the underlying pathology in∼20% of all sudden cardiac deaths (SCDs). Heavy drinking is known to be associated with SCD due to ischaemic heart disease, but studies on association of recent alcohol consumption and SCD in patients with NIHD are scarce. We evaluated the blood alcohol levels of autopsy verified non-ischaemic SCD victims. Methods: Study population was derived from the Finnish Genetic Study of Arrhythmic Events (Fingesture) (n = 5869, mean age 65 ± 12, 79% males). All deaths occurred in Northern Finland during 1998–2017. All victims underwent a medico-legal autopsy. Subjects of SCD due to ischaemic heart disease were excluded. Results: A total of 1301 (mean age 57 ± 12, 78% males) victims of SCD due to NIHD were included in the study. The blood ethanol level was elevated in 543 (42%) subjects, out of which the blood alcohol level was ≥0.10%in 339 (62%) subjects and ≥0.15%in 252 (46%) subjects. Male SCD victims had alcohol in blood more frequently compared to females (45% versus 31%, p < .001). Conclusion: Elevated blood alcohol level is common in SCD victims due to NIHD, especially in males. Recent alcohol consumption might contribute to the subsequent SCD in many non-ischaemic SCD victims. |
format |
Article in Journal/Newspaper |
author |
Kauppila, J. P. (Janna P.) Pakanen, L. (Lasse) Porvari, K. (Katja) Vähätalo, J. (Juha) Holmström, L. (Lauri) Perkiömäki, J. S. (Juha S.) Huikuri, H. V. (Heikki V.) Junttila, M. J. (M. Juhani) |
author_facet |
Kauppila, J. P. (Janna P.) Pakanen, L. (Lasse) Porvari, K. (Katja) Vähätalo, J. (Juha) Holmström, L. (Lauri) Perkiömäki, J. S. (Juha S.) Huikuri, H. V. (Heikki V.) Junttila, M. J. (M. Juhani) |
author_sort |
Kauppila, J. P. (Janna P.) |
title |
Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death |
title_short |
Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death |
title_full |
Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death |
title_fullStr |
Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death |
title_full_unstemmed |
Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death |
title_sort |
blood alcohol levels in finnish victims of non-ischaemic sudden cardiac death |
publisher |
Informa |
publishDate |
2021 |
url |
http://urn.fi/urn:nbn:fi-fe2021042211424 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_rights |
info:eu-repo/semantics/openAccess © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/ |
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1772818036112228352 |