Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition
Abstract The purpose of the study was to examine the cold-induced effects on pineal and thyroid hormones, as well as the associations of these hormones with psychological performance and to determine how psychological performance could be affected by demographic, anthropometric, physiological or bio...
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University of Oulu
2010
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ftunivoulu:oai:oulu.fi:isbn978-951-42-6121-3 2023-07-30T03:59:18+02:00 Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition Pääkkönen, T. (Tiina) 2010-02-16 application/pdf http://urn.fi/urn:isbn:9789514261213 eng eng University of Oulu info:eu-repo/semantics/altIdentifier/pissn/0355-3221 info:eu-repo/semantics/altIdentifier/eissn/1796-2234 info:eu-repo/semantics/openAccess © University of Oulu, 2010 acclimatisation cognition cold climate cold temperature darkness environmental exposure light melatonin seasons thyroid hormones akklimatisaatio kilpirauhashormonit kylmä ilmasto kylmä lämpötila melatoniini pimeys valo vuodenajat ympäristöaltistus älyllinen toimintakyky info:eu-repo/semantics/doctoralThesis info:eu-repo/semantics/publishedVersion 2010 ftunivoulu 2023-07-08T19:53:26Z Abstract The purpose of the study was to examine the cold-induced effects on pineal and thyroid hormones, as well as the associations of these hormones with psychological performance and to determine how psychological performance could be affected by demographic, anthropometric, physiological or biochemical measures during cold acclimatisation. The feasibility of urinary melatonin (MT), rather than 6-sulphatoxymelatonin (aMT6s), as an indicator of MT secretion was also examined. In the laboratory study, seasonal cold acclimatisation, its effects on hormones and their associations with mood and cognition were assessed in 15 young urban subjects exposed to cold in winter or summer in bright or dim light. In the field study, the associations of mood and cognition with demographic, anthropometric, physiological and biochemical measures were determined in healthy, euthyroid subjects (n = 133) in Antarctica in the beginning and at the end of summer and winter seasons. In both seasons, simple task performance was consistently impaired in the cold in experimental and field conditions. In complex tasks, negative, positive and mixed effects were observed. In the experimental study, serum MT and thyroid hormone levels were positively associated with mood. MT was negatively associated with simple task performance. Free triiodothyronine (T3) and thyrotropin (TSH) had mixed effects on simple task performance. TSH was positively associated with complex task performance. In the field study, higher age was associated with impaired cognition, especially in complex task performance. Total T3 was positively associated with mood and total thyroxine (T4) with complex task accuracy. Both urinary MT and aMT6s were good indicators of MT secretion, but the variation was smaller for MT. In conclusion, the associations of serum MT, TSH and thyroid hormone levels with mood and cognition found in experimental and field conditions are consistent with the psychological changes associated with the onset and consequent stages of the previously ... Doctoral or Postdoctoral Thesis Antarc* Antarctica Jultika - University of Oulu repository |
institution |
Open Polar |
collection |
Jultika - University of Oulu repository |
op_collection_id |
ftunivoulu |
language |
English |
topic |
acclimatisation cognition cold climate cold temperature darkness environmental exposure light melatonin seasons thyroid hormones akklimatisaatio kilpirauhashormonit kylmä ilmasto kylmä lämpötila melatoniini pimeys valo vuodenajat ympäristöaltistus älyllinen toimintakyky |
spellingShingle |
acclimatisation cognition cold climate cold temperature darkness environmental exposure light melatonin seasons thyroid hormones akklimatisaatio kilpirauhashormonit kylmä ilmasto kylmä lämpötila melatoniini pimeys valo vuodenajat ympäristöaltistus älyllinen toimintakyky Pääkkönen, T. (Tiina) Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
topic_facet |
acclimatisation cognition cold climate cold temperature darkness environmental exposure light melatonin seasons thyroid hormones akklimatisaatio kilpirauhashormonit kylmä ilmasto kylmä lämpötila melatoniini pimeys valo vuodenajat ympäristöaltistus älyllinen toimintakyky |
description |
Abstract The purpose of the study was to examine the cold-induced effects on pineal and thyroid hormones, as well as the associations of these hormones with psychological performance and to determine how psychological performance could be affected by demographic, anthropometric, physiological or biochemical measures during cold acclimatisation. The feasibility of urinary melatonin (MT), rather than 6-sulphatoxymelatonin (aMT6s), as an indicator of MT secretion was also examined. In the laboratory study, seasonal cold acclimatisation, its effects on hormones and their associations with mood and cognition were assessed in 15 young urban subjects exposed to cold in winter or summer in bright or dim light. In the field study, the associations of mood and cognition with demographic, anthropometric, physiological and biochemical measures were determined in healthy, euthyroid subjects (n = 133) in Antarctica in the beginning and at the end of summer and winter seasons. In both seasons, simple task performance was consistently impaired in the cold in experimental and field conditions. In complex tasks, negative, positive and mixed effects were observed. In the experimental study, serum MT and thyroid hormone levels were positively associated with mood. MT was negatively associated with simple task performance. Free triiodothyronine (T3) and thyrotropin (TSH) had mixed effects on simple task performance. TSH was positively associated with complex task performance. In the field study, higher age was associated with impaired cognition, especially in complex task performance. Total T3 was positively associated with mood and total thyroxine (T4) with complex task accuracy. Both urinary MT and aMT6s were good indicators of MT secretion, but the variation was smaller for MT. In conclusion, the associations of serum MT, TSH and thyroid hormone levels with mood and cognition found in experimental and field conditions are consistent with the psychological changes associated with the onset and consequent stages of the previously ... |
format |
Doctoral or Postdoctoral Thesis |
author |
Pääkkönen, T. (Tiina) |
author_facet |
Pääkkönen, T. (Tiina) |
author_sort |
Pääkkönen, T. (Tiina) |
title |
Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
title_short |
Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
title_full |
Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
title_fullStr |
Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
title_full_unstemmed |
Melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
title_sort |
melatonin and thyroid hormones in the cold and in darkness:association with mood and cognition |
publisher |
University of Oulu |
publishDate |
2010 |
url |
http://urn.fi/urn:isbn:9789514261213 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
info:eu-repo/semantics/altIdentifier/pissn/0355-3221 info:eu-repo/semantics/altIdentifier/eissn/1796-2234 |
op_rights |
info:eu-repo/semantics/openAccess © University of Oulu, 2010 |
_version_ |
1772810061044776960 |