CARBOXYLATIONS AND DECARBOXYLATIONS
A brief survey of decarboxylation reactions and carboxylation reactions that are known or presumed in biological systems will be presented. While a considerable number of amino acid decarboxylations are known, their mechanisms will not be included in the present discussion but will be reserved for a...
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Lawrence Berkeley National Laboratory
1959
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ftunivnotexas:info:ark/67531/metadc896532 2023-05-15T15:52:48+02:00 CARBOXYLATIONS AND DECARBOXYLATIONS Calvin, Melvin Pon, Ning G. U.S. Atomic Energy Commission 1959-04-21 49 p. Text https://doi.org/10.2172/919681 http://digital.library.unt.edu/ark:/67531/metadc896532/ English eng Lawrence Berkeley National Laboratory rep-no: UCRL--8732 grantno: DE-AC02-05CH11231 doi:10.2172/919681 osti: 919681 http://digital.library.unt.edu/ark:/67531/metadc896532/ ark: ark:/67531/metadc896532 Decarboxylation Enzymes Carbon Dioxide Carboxylation 59 Basic Biological Sciences Enols Reaction Kinetics Ribulose Pyridine Nucleotides Substrates Report 1959 ftunivnotexas https://doi.org/10.2172/919681 2016-11-05T23:11:58Z A brief survey of decarboxylation reactions and carboxylation reactions that are known or presumed in biological systems will be presented. While a considerable number of amino acid decarboxylations are known, their mechanisms will not be included in the present discussion but will be reserved for a later paper in the symposium. The remaining decarboxylation reactions may be subdivided into oxidative and nonoxidative decarboxylations. In most cases, these reactions are practically irreversible except when coupled with suitable energy-yielding systems. The carboxylation reactions which are useful in the formation of carbon-carbon bonds in biological systems seem to fall into two or three groups: those which exhibit an apparent ATP requirement, and those which exhibit a reduced pyridine nucleotide requirement, and those which exhibit no apparent ATP requirement. Of the first group at least four cases, and possibly six or seven, are known, and one interpretation of them involves the preliminary formation of 'active' carbon dioxide, generally in the form of a carbonic acid-phosphoric acid anhydride. Those exhibiting no apparent ATP requirement seem to be susceptible to classifications as enol carboxylations in which the energy level of the substrate compound is high, rather than that of the carbon dioxide. There appear to be at least three examples of this latter type known, amongs them being the carboxy-dismutase reaction of ribulose diphosphate with carbon dioxide. Report Carbonic acid University of North Texas: UNT Digital Library |
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University of North Texas: UNT Digital Library |
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ftunivnotexas |
language |
English |
topic |
Decarboxylation Enzymes Carbon Dioxide Carboxylation 59 Basic Biological Sciences Enols Reaction Kinetics Ribulose Pyridine Nucleotides Substrates |
spellingShingle |
Decarboxylation Enzymes Carbon Dioxide Carboxylation 59 Basic Biological Sciences Enols Reaction Kinetics Ribulose Pyridine Nucleotides Substrates Calvin, Melvin Pon, Ning G. CARBOXYLATIONS AND DECARBOXYLATIONS |
topic_facet |
Decarboxylation Enzymes Carbon Dioxide Carboxylation 59 Basic Biological Sciences Enols Reaction Kinetics Ribulose Pyridine Nucleotides Substrates |
description |
A brief survey of decarboxylation reactions and carboxylation reactions that are known or presumed in biological systems will be presented. While a considerable number of amino acid decarboxylations are known, their mechanisms will not be included in the present discussion but will be reserved for a later paper in the symposium. The remaining decarboxylation reactions may be subdivided into oxidative and nonoxidative decarboxylations. In most cases, these reactions are practically irreversible except when coupled with suitable energy-yielding systems. The carboxylation reactions which are useful in the formation of carbon-carbon bonds in biological systems seem to fall into two or three groups: those which exhibit an apparent ATP requirement, and those which exhibit a reduced pyridine nucleotide requirement, and those which exhibit no apparent ATP requirement. Of the first group at least four cases, and possibly six or seven, are known, and one interpretation of them involves the preliminary formation of 'active' carbon dioxide, generally in the form of a carbonic acid-phosphoric acid anhydride. Those exhibiting no apparent ATP requirement seem to be susceptible to classifications as enol carboxylations in which the energy level of the substrate compound is high, rather than that of the carbon dioxide. There appear to be at least three examples of this latter type known, amongs them being the carboxy-dismutase reaction of ribulose diphosphate with carbon dioxide. |
author2 |
U.S. Atomic Energy Commission |
format |
Report |
author |
Calvin, Melvin Pon, Ning G. |
author_facet |
Calvin, Melvin Pon, Ning G. |
author_sort |
Calvin, Melvin |
title |
CARBOXYLATIONS AND DECARBOXYLATIONS |
title_short |
CARBOXYLATIONS AND DECARBOXYLATIONS |
title_full |
CARBOXYLATIONS AND DECARBOXYLATIONS |
title_fullStr |
CARBOXYLATIONS AND DECARBOXYLATIONS |
title_full_unstemmed |
CARBOXYLATIONS AND DECARBOXYLATIONS |
title_sort |
carboxylations and decarboxylations |
publisher |
Lawrence Berkeley National Laboratory |
publishDate |
1959 |
url |
https://doi.org/10.2172/919681 http://digital.library.unt.edu/ark:/67531/metadc896532/ |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_relation |
rep-no: UCRL--8732 grantno: DE-AC02-05CH11231 doi:10.2172/919681 osti: 919681 http://digital.library.unt.edu/ark:/67531/metadc896532/ ark: ark:/67531/metadc896532 |
op_doi |
https://doi.org/10.2172/919681 |
_version_ |
1766387893496971264 |