Microbial Diversity-Based Novel Crop Protection Products
Extremophilic microorganisms are adapted to survive in ecological niches with high temperatures, extremes of pH, high salt concentrations, high pressure, radiation, etc. Extremophiles produce unique biocatalysts and natural products that function under extreme conditions comparab le to those prevail...
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Lawrence Berkeley National Laboratory
2007
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Online Access: | https://digital.library.unt.edu/ark:/67531/metadc835206/ |
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ftunivnotexas:info:ark/67531/metadc835206 2023-05-15T16:59:20+02:00 Microbial Diversity-Based Novel Crop Protection Products Inc., Pioneer Hi-Bred International Station, DuPont Experimental Yalpani, Ronald Flannagan, Rafael Herrmann, James Presnail, Tamas Torok, and Nasser Herrmann, Rafael Presnail, James Torok, Tamas Yalpani, Nasser Lawrence Berkeley National Laboratory. Life Sciences Division. 2007-05-10 1 Text https://digital.library.unt.edu/ark:/67531/metadc835206/ English eng Lawrence Berkeley National Laboratory rep-no: LBNL-4686E-Poster grantno: DE-AC02-05CH11231 osti: 1023379 https://digital.library.unt.edu/ark:/67531/metadc835206/ ark: ark:/67531/metadc835206 ASM General Meeting, Toronto, Canada, May 20-25, 2007 Crop Protection Microorganisms Insects Genes Food Crops Fungi 60 Nuclear Power Plants Extremophiles Peptides Extremophiles Biotechnology Agriculture Bacteria Antifungal Polypeptide Fermentation Article 2007 ftunivnotexas 2019-03-23T23:08:08Z Extremophilic microorganisms are adapted to survive in ecological niches with high temperatures, extremes of pH, high salt concentrations, high pressure, radiation, etc. Extremophiles produce unique biocatalysts and natural products that function under extreme conditions comparab le to those prevailing in various industrial processes. Therefore, there is burgeoning interest in bioprospecting for extremophiles with potential immediate use in agriculture, the food, chemical, and pharm aceutical industries, and environmental biotechnology. Over the years, several thousand extremophilic bacteria, archaea, and filamentous fungi were collected at extreme environmental sites in the USA, the Chernobyl Exclusion Zone surrounding the faeild nuclear power plant in Ukraine, in and around Lake Baikal in Siberia, and at geothermal sites on the Kamchatka peninsula in Russia. These organisms were cultured under proprietary conditions, and the cell- free supernatants were screened for biological activities against plant pathogenic fungi and major crop damaging insects. Promising peptide lead molecules were isolated, characterized, and sequenced. Relatively high hit rates characterized the tested fermentation broths. Of the 26,000 samples screened, over thousand contained biological activity of interest. A fair number of microorganisms expressed broad- spectrum antifungal or insecticidal activity. Two- dozen broadly antifungal peptides (AFPs) are alr eady patent protected, and many more tens are under further investigation. Tapping the gene pool of extremophilic microorganisms to provide novel ways of crop protection proved a successful strategy. Article in Journal/Newspaper Kamchatka Kamchatka Peninsula Siberia University of North Texas: UNT Digital Library Kamchatka Peninsula ENVELOPE(160.000,160.000,56.000,56.000) |
institution |
Open Polar |
collection |
University of North Texas: UNT Digital Library |
op_collection_id |
ftunivnotexas |
language |
English |
topic |
Crop Protection Microorganisms Insects Genes Food Crops Fungi 60 Nuclear Power Plants Extremophiles Peptides Extremophiles Biotechnology Agriculture Bacteria Antifungal Polypeptide Fermentation |
spellingShingle |
Crop Protection Microorganisms Insects Genes Food Crops Fungi 60 Nuclear Power Plants Extremophiles Peptides Extremophiles Biotechnology Agriculture Bacteria Antifungal Polypeptide Fermentation Inc., Pioneer Hi-Bred International Station, DuPont Experimental Yalpani, Ronald Flannagan, Rafael Herrmann, James Presnail, Tamas Torok, and Nasser Herrmann, Rafael Presnail, James Torok, Tamas Yalpani, Nasser Microbial Diversity-Based Novel Crop Protection Products |
topic_facet |
Crop Protection Microorganisms Insects Genes Food Crops Fungi 60 Nuclear Power Plants Extremophiles Peptides Extremophiles Biotechnology Agriculture Bacteria Antifungal Polypeptide Fermentation |
description |
Extremophilic microorganisms are adapted to survive in ecological niches with high temperatures, extremes of pH, high salt concentrations, high pressure, radiation, etc. Extremophiles produce unique biocatalysts and natural products that function under extreme conditions comparab le to those prevailing in various industrial processes. Therefore, there is burgeoning interest in bioprospecting for extremophiles with potential immediate use in agriculture, the food, chemical, and pharm aceutical industries, and environmental biotechnology. Over the years, several thousand extremophilic bacteria, archaea, and filamentous fungi were collected at extreme environmental sites in the USA, the Chernobyl Exclusion Zone surrounding the faeild nuclear power plant in Ukraine, in and around Lake Baikal in Siberia, and at geothermal sites on the Kamchatka peninsula in Russia. These organisms were cultured under proprietary conditions, and the cell- free supernatants were screened for biological activities against plant pathogenic fungi and major crop damaging insects. Promising peptide lead molecules were isolated, characterized, and sequenced. Relatively high hit rates characterized the tested fermentation broths. Of the 26,000 samples screened, over thousand contained biological activity of interest. A fair number of microorganisms expressed broad- spectrum antifungal or insecticidal activity. Two- dozen broadly antifungal peptides (AFPs) are alr eady patent protected, and many more tens are under further investigation. Tapping the gene pool of extremophilic microorganisms to provide novel ways of crop protection proved a successful strategy. |
author2 |
Lawrence Berkeley National Laboratory. Life Sciences Division. |
format |
Article in Journal/Newspaper |
author |
Inc., Pioneer Hi-Bred International Station, DuPont Experimental Yalpani, Ronald Flannagan, Rafael Herrmann, James Presnail, Tamas Torok, and Nasser Herrmann, Rafael Presnail, James Torok, Tamas Yalpani, Nasser |
author_facet |
Inc., Pioneer Hi-Bred International Station, DuPont Experimental Yalpani, Ronald Flannagan, Rafael Herrmann, James Presnail, Tamas Torok, and Nasser Herrmann, Rafael Presnail, James Torok, Tamas Yalpani, Nasser |
author_sort |
Inc., Pioneer Hi-Bred International |
title |
Microbial Diversity-Based Novel Crop Protection Products |
title_short |
Microbial Diversity-Based Novel Crop Protection Products |
title_full |
Microbial Diversity-Based Novel Crop Protection Products |
title_fullStr |
Microbial Diversity-Based Novel Crop Protection Products |
title_full_unstemmed |
Microbial Diversity-Based Novel Crop Protection Products |
title_sort |
microbial diversity-based novel crop protection products |
publisher |
Lawrence Berkeley National Laboratory |
publishDate |
2007 |
url |
https://digital.library.unt.edu/ark:/67531/metadc835206/ |
long_lat |
ENVELOPE(160.000,160.000,56.000,56.000) |
geographic |
Kamchatka Peninsula |
geographic_facet |
Kamchatka Peninsula |
genre |
Kamchatka Kamchatka Peninsula Siberia |
genre_facet |
Kamchatka Kamchatka Peninsula Siberia |
op_source |
ASM General Meeting, Toronto, Canada, May 20-25, 2007 |
op_relation |
rep-no: LBNL-4686E-Poster grantno: DE-AC02-05CH11231 osti: 1023379 https://digital.library.unt.edu/ark:/67531/metadc835206/ ark: ark:/67531/metadc835206 |
_version_ |
1766051583955566592 |