Values of hematological and biochemical parameters of domesticated and reproduced rodents in the Bioterium Jorge Basadre Grohmann National University

• Main Authors: Velasco Lopez, Lucio, Valdivia Quispe, Lesly Adelis
• Format: Article in Journal/Newspaper
• Language: Spanish
• Published: Fondo Editorial UNJBG 2023
• Subjects: Bioquímico; fisiológico; hematológico; parámetros; salud; Biochemical; physiological; hematological; parameters; health; Rattus rattus
• Online Access: https://revistas.unjbg.edu.pe/index.php/recibya/article/view/1875; https://doi.org/10.33326/29585309.2023.1.1875

The study used rats as biological models. The range of normal values is an indispensable tool for experiments with animals, because they can evaluate the health status of the animal, while helping to detect differences in the behavior of the animal's physiological parameters during the experiments. However, few articles describe its normal physiological parameters. The objective of this study is to establish the values of the normal parameters of the main hematological and biochemical variables in rats raised and produced in the bioterium of the Jorge Basadre Grohmann National University. The study used data from 100 rats (Rattus norvegicus – Rattus rattus) in its five varieties represented by 20 individuals each variety, of both genders, 30 weeks old. The hematological parameters analyzed were: WBC, Neu, Eos, Bas, Lym, Mon, Gran, RBC, HGB, HCT, MCV, MCH, MCHC, RDW, PLT, MPV, PDW, PCT. With respect to the biochemical parameters they were: Albumin, Glucose, Urea, Triglycerides, Globulin, Alkaline Phosphatase, Creatinine, GGT, GOT/AST, GPT/ALT, Total proteins, Uric acid. The results obtained were able to determine the hematological and biochemical parameters of the rats domesticated and reproduced in the bioterium, allowing a comprehensive analysis of the animal's health. En el estudio se utilizaron las ratas como modelos biológicos. El rango de los valores normales es una herramienta indispensable para los experimentos con animales porque pueden evaluar el estado de salud del animal, a la vez que ayuda a detectar diferencias en el comportamiento de los parámetros fisiológicos del animal durante los experimentos; sin embargo, pocos artículos describen sus parámetros fisiológicos normales. El objetivo del estudio fue establecer los valores de los parámetros de normalidad de las principales variables hematológicas y bioquímicas en ratas criadas y producidas en el Bioterio de la Universidad Nacional Jorge Basadre Grohmann. En el estudio se utilizaron datos de 100 ratas (Rattus norvegicus - Rattus rattus) en sus ...