Breast cancer screening case-control study design: impact on breast cancer mortality
Item does not contain fulltext BACKGROUND: Recent case-control studies on the effectiveness of population-based breast cancer screening show differences in the magnitude of breast cancer mortality reduction. We investigated the role played by aspects of the case-control study design on these differe...
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Online Access: | http://hdl.handle.net/2066/97689 https://doi.org/10.1093/annonc/mdq447 |
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ftunivnijmegen:oai:repository.ubn.ru.nl:2066/97689 2023-05-15T16:51:14+02:00 Breast cancer screening case-control study design: impact on breast cancer mortality Paap, E. Verbeek, A.L.M. Puliti, D. Paci, E. Broeders, M.J.M. 2011 http://hdl.handle.net/2066/97689 https://doi.org/10.1093/annonc/mdq447 unknown http://hdl.handle.net/2066/97689 https://doi.org/10.1093/annonc/mdq447 Annals of Oncology, 22, 4, pp. 863-9 NCEBP 1: Molecular epidemiology ONCOL 5: Aetiology screening and detection NCEBP 2: Evaluation of complex medical interventions ONCOL 5: Aetiology Article / Letter to editor 2011 ftunivnijmegen https://doi.org/10.1093/annonc/mdq447 2022-12-21T23:18:09Z Item does not contain fulltext BACKGROUND: Recent case-control studies on the effectiveness of population-based breast cancer screening show differences in the magnitude of breast cancer mortality reduction. We investigated the role played by aspects of the case-control study design on these differences, e.g. the definition of cases and exposure to screening. MATERIAL AND METHODS: We investigated six case-control studies conducted in East Anglia (UK), Wales, Iceland, central and northern Italy, South Australia and The Netherlands. RESULTS: The breast cancer mortality reduction in the different case-control studies ranged from 38% to 70% in the screened versus the nonscreened women. We identified differences in design, e.g. the inclusion or exclusion of the first years of screening, and the correction factor for self-selection bias. CONCLUSIONS: Overall, the design of the case-control studies was similar. The differences in the magnitude of breast cancer mortality reductions are therefore unlikely to be caused by variations in the design of the case-control studies. These differences must be due to other factors, like the organisation of the service screening programme and the attendance rate. The reduction in breast cancer mortality estimated in these case-control studies indicates that the impact of current mammographic screening is at least consistent with the effect reported by the former randomised screening trials. Article in Journal/Newspaper Iceland Radboud University: DSpace Annals of Oncology 22 4 863 869 |
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Radboud University: DSpace |
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ftunivnijmegen |
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unknown |
topic |
NCEBP 1: Molecular epidemiology ONCOL 5: Aetiology screening and detection NCEBP 2: Evaluation of complex medical interventions ONCOL 5: Aetiology |
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NCEBP 1: Molecular epidemiology ONCOL 5: Aetiology screening and detection NCEBP 2: Evaluation of complex medical interventions ONCOL 5: Aetiology Paap, E. Verbeek, A.L.M. Puliti, D. Paci, E. Broeders, M.J.M. Breast cancer screening case-control study design: impact on breast cancer mortality |
topic_facet |
NCEBP 1: Molecular epidemiology ONCOL 5: Aetiology screening and detection NCEBP 2: Evaluation of complex medical interventions ONCOL 5: Aetiology |
description |
Item does not contain fulltext BACKGROUND: Recent case-control studies on the effectiveness of population-based breast cancer screening show differences in the magnitude of breast cancer mortality reduction. We investigated the role played by aspects of the case-control study design on these differences, e.g. the definition of cases and exposure to screening. MATERIAL AND METHODS: We investigated six case-control studies conducted in East Anglia (UK), Wales, Iceland, central and northern Italy, South Australia and The Netherlands. RESULTS: The breast cancer mortality reduction in the different case-control studies ranged from 38% to 70% in the screened versus the nonscreened women. We identified differences in design, e.g. the inclusion or exclusion of the first years of screening, and the correction factor for self-selection bias. CONCLUSIONS: Overall, the design of the case-control studies was similar. The differences in the magnitude of breast cancer mortality reductions are therefore unlikely to be caused by variations in the design of the case-control studies. These differences must be due to other factors, like the organisation of the service screening programme and the attendance rate. The reduction in breast cancer mortality estimated in these case-control studies indicates that the impact of current mammographic screening is at least consistent with the effect reported by the former randomised screening trials. |
format |
Article in Journal/Newspaper |
author |
Paap, E. Verbeek, A.L.M. Puliti, D. Paci, E. Broeders, M.J.M. |
author_facet |
Paap, E. Verbeek, A.L.M. Puliti, D. Paci, E. Broeders, M.J.M. |
author_sort |
Paap, E. |
title |
Breast cancer screening case-control study design: impact on breast cancer mortality |
title_short |
Breast cancer screening case-control study design: impact on breast cancer mortality |
title_full |
Breast cancer screening case-control study design: impact on breast cancer mortality |
title_fullStr |
Breast cancer screening case-control study design: impact on breast cancer mortality |
title_full_unstemmed |
Breast cancer screening case-control study design: impact on breast cancer mortality |
title_sort |
breast cancer screening case-control study design: impact on breast cancer mortality |
publishDate |
2011 |
url |
http://hdl.handle.net/2066/97689 https://doi.org/10.1093/annonc/mdq447 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Annals of Oncology, 22, 4, pp. 863-9 |
op_relation |
http://hdl.handle.net/2066/97689 https://doi.org/10.1093/annonc/mdq447 |
op_doi |
https://doi.org/10.1093/annonc/mdq447 |
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Annals of Oncology |
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22 |
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4 |
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863 |
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869 |
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1766041346176450560 |