Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California
A field study addressing causes of mortality in freshly dead northern elephant seals (Mirounga angustirostris, Gill, 1866) was conducted on San Miguel Island, California, in February 2015. Necropsies were performed on 18 pups ranging in age from stillbirths to approximately 7 to 8 weeks. The primary...
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ftunivnebraskali:oai:digitalcommons.unl.edu:usdeptcommercepub-1633 2024-06-23T07:52:28+00:00 Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California Spraker, Terry R. Kuzmina, Tetiana A. Lyons, Eugene T. DeLong, Robert L. Simeone, Claire Veeramachaneni, D. N. Rao 2019-01-01T08:00:00Z application/pdf https://digitalcommons.unl.edu/usdeptcommercepub/618 https://digitalcommons.unl.edu/context/usdeptcommercepub/article/1633/viewcontent/Spraker_VP_2019_Multifocal_Necrotizing.pdf unknown DigitalCommons@University of Nebraska - Lincoln https://digitalcommons.unl.edu/usdeptcommercepub/618 https://digitalcommons.unl.edu/context/usdeptcommercepub/article/1633/viewcontent/Spraker_VP_2019_Multifocal_Necrotizing.pdf United States Department of Commerce: Staff Publications marine mammals Mirounga angustirostris muscle myopathy seals San Miguel Island text 2019 ftunivnebraskali 2024-06-05T03:31:38Z A field study addressing causes of mortality in freshly dead northern elephant seals (Mirounga angustirostris, Gill, 1866) was conducted on San Miguel Island, California, in February 2015. Necropsies were performed on 18 pups ranging in age from stillbirths to approximately 7 to 8 weeks. The primary gross diagnoses in these pups included trauma, myopathy, starvation/ emaciation, infections, congenital anomalies, and perinatal mortality. However, 6 (33%) had a previously unrecognized myopathy characterized by multiple white streaks that were most obvious within the inner layer of the abdominal wall and the small innermost ventral intercostal muscles. Following histological examination, 2 more pups from San Miguel Island and 6 pups from The Marine Mammal Center (Sausalito, California) were found to have similar lesions. Histologically, the lesions within the skeletal muscles were characterized by a multifocal polyphasic, mild to severe, acute to subacute necrotizing myopathy with mineralization. Acute necrosis and degeneration characterized by pyknotic nuclei, eosinophilic cytoplasm and cytoplasmic vacuolization were found in smooth muscle myocytes within the urinary bladder and digestive system. Degeneration of myocytes was present in the tunica media of a few small- to medium-sized vessels and was characterized by a vacuolar degeneration and occasionally necrosis. This condition has been termed multifocal necrotizing myopathy. A cause of this myopathy was not identified. Text Elephant Seal Elephant Seals University of Nebraska-Lincoln: DigitalCommons@UNL San Miguel ENVELOPE(-57.467,-57.467,-63.650,-63.650) |
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Open Polar |
collection |
University of Nebraska-Lincoln: DigitalCommons@UNL |
op_collection_id |
ftunivnebraskali |
language |
unknown |
topic |
marine mammals Mirounga angustirostris muscle myopathy seals San Miguel Island |
spellingShingle |
marine mammals Mirounga angustirostris muscle myopathy seals San Miguel Island Spraker, Terry R. Kuzmina, Tetiana A. Lyons, Eugene T. DeLong, Robert L. Simeone, Claire Veeramachaneni, D. N. Rao Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California |
topic_facet |
marine mammals Mirounga angustirostris muscle myopathy seals San Miguel Island |
description |
A field study addressing causes of mortality in freshly dead northern elephant seals (Mirounga angustirostris, Gill, 1866) was conducted on San Miguel Island, California, in February 2015. Necropsies were performed on 18 pups ranging in age from stillbirths to approximately 7 to 8 weeks. The primary gross diagnoses in these pups included trauma, myopathy, starvation/ emaciation, infections, congenital anomalies, and perinatal mortality. However, 6 (33%) had a previously unrecognized myopathy characterized by multiple white streaks that were most obvious within the inner layer of the abdominal wall and the small innermost ventral intercostal muscles. Following histological examination, 2 more pups from San Miguel Island and 6 pups from The Marine Mammal Center (Sausalito, California) were found to have similar lesions. Histologically, the lesions within the skeletal muscles were characterized by a multifocal polyphasic, mild to severe, acute to subacute necrotizing myopathy with mineralization. Acute necrosis and degeneration characterized by pyknotic nuclei, eosinophilic cytoplasm and cytoplasmic vacuolization were found in smooth muscle myocytes within the urinary bladder and digestive system. Degeneration of myocytes was present in the tunica media of a few small- to medium-sized vessels and was characterized by a vacuolar degeneration and occasionally necrosis. This condition has been termed multifocal necrotizing myopathy. A cause of this myopathy was not identified. |
format |
Text |
author |
Spraker, Terry R. Kuzmina, Tetiana A. Lyons, Eugene T. DeLong, Robert L. Simeone, Claire Veeramachaneni, D. N. Rao |
author_facet |
Spraker, Terry R. Kuzmina, Tetiana A. Lyons, Eugene T. DeLong, Robert L. Simeone, Claire Veeramachaneni, D. N. Rao |
author_sort |
Spraker, Terry R. |
title |
Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California |
title_short |
Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California |
title_full |
Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California |
title_fullStr |
Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California |
title_full_unstemmed |
Multifocal Necrotizing Myopathy in Northern Elephant Seal ( Mirounga angustirostris ) Pups, San Miguel Island, California |
title_sort |
multifocal necrotizing myopathy in northern elephant seal ( mirounga angustirostris ) pups, san miguel island, california |
publisher |
DigitalCommons@University of Nebraska - Lincoln |
publishDate |
2019 |
url |
https://digitalcommons.unl.edu/usdeptcommercepub/618 https://digitalcommons.unl.edu/context/usdeptcommercepub/article/1633/viewcontent/Spraker_VP_2019_Multifocal_Necrotizing.pdf |
long_lat |
ENVELOPE(-57.467,-57.467,-63.650,-63.650) |
geographic |
San Miguel |
geographic_facet |
San Miguel |
genre |
Elephant Seal Elephant Seals |
genre_facet |
Elephant Seal Elephant Seals |
op_source |
United States Department of Commerce: Staff Publications |
op_relation |
https://digitalcommons.unl.edu/usdeptcommercepub/618 https://digitalcommons.unl.edu/context/usdeptcommercepub/article/1633/viewcontent/Spraker_VP_2019_Multifocal_Necrotizing.pdf |
_version_ |
1802643779471015936 |