TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA
Transmission dynamics of Toxoplasma gondii, a parasite of importance for wildlife and human health, are enigmatic in the Arctic tundra, where free-ranging wild and domestic felid definitive hosts are absent and rarely observed, respectively. Through a multiyear mark-recapture study (2011– 17), seros...
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ftunivnebraskali:oai:digitalcommons.unl.edu:icwdm_usdanwrc-3263 2023-11-12T04:10:28+01:00 TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA Bouchard, Emilie Elmore, Stacey A. Alisauskas, Ray T. Samelius, Gustaf Gajadhar, Alvin A. Schmidt, Keaton Ross, Sasha Jenkins, Emily J. 2019-07-01T07:00:00Z application/pdf https://digitalcommons.unl.edu/icwdm_usdanwrc/2264 https://digitalcommons.unl.edu/context/icwdm_usdanwrc/article/3263/viewcontent/Bouchard_JWD_2019_TRANSMISSION_DYNAMICS.pdf unknown DigitalCommons@University of Nebraska - Lincoln https://digitalcommons.unl.edu/icwdm_usdanwrc/2264 https://digitalcommons.unl.edu/context/icwdm_usdanwrc/article/3263/viewcontent/Bouchard_JWD_2019_TRANSMISSION_DYNAMICS.pdf USDA Wildlife Services - Staff Publications Arctic fox IFAT Karrak Lake MAT Toxoplasma vertical transmission Animal Sciences Environmental Sciences Life Sciences Natural Resources and Conservation Natural Resources Management and Policy Other Environmental Sciences Other Veterinary Medicine Population Biology Terrestrial and Aquatic Ecology Veterinary Infectious Diseases Veterinary Medicine Veterinary Microbiology and Immunobiology Veterinary Preventive Medicine Epidemiology and Public Health Zoology text 2019 ftunivnebraskali 2023-10-30T11:49:54Z Transmission dynamics of Toxoplasma gondii, a parasite of importance for wildlife and human health, are enigmatic in the Arctic tundra, where free-ranging wild and domestic felid definitive hosts are absent and rarely observed, respectively. Through a multiyear mark-recapture study (2011– 17), serosurveillance was conducted to investigate transmission of T. gondii in Arctic foxes (Vulpes lagopus) in the Karrak Lake region, Nunavut, Canada. Sera from adult foxes and fox pups were tested for antibodies to T. gondii by using serologic methods, including the indirect fluorescent antibody test, direct agglutination test, and modified agglutination test. The overall seroprevalence was 39% in adults and 17% in pups. Mature foxes were more likely to be exposed (seroconvert) than young foxes (less than 1 yr old), with the highest level of seroprevalence in midaged foxes (2–4 yr old). Pups in two different litters were seropositive on emergence from the den, around 5 wk old, which could have been due to passive transfer of maternal antibody or vertical transmission of T. gondii from mother to offspring. The seropositive pups were born of seropositive mothers that were also seropositive the year before they gave birth, suggesting that vertical transmission might not be limited to litters from mothers exposed to T. gondii for the first time in pregnancy. All recaptured seropositive foxes remained seropositive on subsequent captures, suggesting that antibodies persist or foxes are constantly reexposed or a combination of both. The results of this study provided insights into how foxes were likely exposed to T. gondii, the dynamics of antibody persistence and immune response, and how the parasite was maintained in a terrestrial Arctic ecosystem in the absence of felid definitive hosts. Text Arctic Fox Arctic Human health Nunavut Tundra Vulpes lagopus University of Nebraska-Lincoln: DigitalCommons@UNL Arctic Nunavut Canada Karrak Lake ENVELOPE(-100.250,-100.250,67.250,67.250) |
institution |
Open Polar |
collection |
University of Nebraska-Lincoln: DigitalCommons@UNL |
op_collection_id |
ftunivnebraskali |
language |
unknown |
topic |
Arctic fox IFAT Karrak Lake MAT Toxoplasma vertical transmission Animal Sciences Environmental Sciences Life Sciences Natural Resources and Conservation Natural Resources Management and Policy Other Environmental Sciences Other Veterinary Medicine Population Biology Terrestrial and Aquatic Ecology Veterinary Infectious Diseases Veterinary Medicine Veterinary Microbiology and Immunobiology Veterinary Preventive Medicine Epidemiology and Public Health Zoology |
spellingShingle |
Arctic fox IFAT Karrak Lake MAT Toxoplasma vertical transmission Animal Sciences Environmental Sciences Life Sciences Natural Resources and Conservation Natural Resources Management and Policy Other Environmental Sciences Other Veterinary Medicine Population Biology Terrestrial and Aquatic Ecology Veterinary Infectious Diseases Veterinary Medicine Veterinary Microbiology and Immunobiology Veterinary Preventive Medicine Epidemiology and Public Health Zoology Bouchard, Emilie Elmore, Stacey A. Alisauskas, Ray T. Samelius, Gustaf Gajadhar, Alvin A. Schmidt, Keaton Ross, Sasha Jenkins, Emily J. TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA |
topic_facet |
Arctic fox IFAT Karrak Lake MAT Toxoplasma vertical transmission Animal Sciences Environmental Sciences Life Sciences Natural Resources and Conservation Natural Resources Management and Policy Other Environmental Sciences Other Veterinary Medicine Population Biology Terrestrial and Aquatic Ecology Veterinary Infectious Diseases Veterinary Medicine Veterinary Microbiology and Immunobiology Veterinary Preventive Medicine Epidemiology and Public Health Zoology |
description |
Transmission dynamics of Toxoplasma gondii, a parasite of importance for wildlife and human health, are enigmatic in the Arctic tundra, where free-ranging wild and domestic felid definitive hosts are absent and rarely observed, respectively. Through a multiyear mark-recapture study (2011– 17), serosurveillance was conducted to investigate transmission of T. gondii in Arctic foxes (Vulpes lagopus) in the Karrak Lake region, Nunavut, Canada. Sera from adult foxes and fox pups were tested for antibodies to T. gondii by using serologic methods, including the indirect fluorescent antibody test, direct agglutination test, and modified agglutination test. The overall seroprevalence was 39% in adults and 17% in pups. Mature foxes were more likely to be exposed (seroconvert) than young foxes (less than 1 yr old), with the highest level of seroprevalence in midaged foxes (2–4 yr old). Pups in two different litters were seropositive on emergence from the den, around 5 wk old, which could have been due to passive transfer of maternal antibody or vertical transmission of T. gondii from mother to offspring. The seropositive pups were born of seropositive mothers that were also seropositive the year before they gave birth, suggesting that vertical transmission might not be limited to litters from mothers exposed to T. gondii for the first time in pregnancy. All recaptured seropositive foxes remained seropositive on subsequent captures, suggesting that antibodies persist or foxes are constantly reexposed or a combination of both. The results of this study provided insights into how foxes were likely exposed to T. gondii, the dynamics of antibody persistence and immune response, and how the parasite was maintained in a terrestrial Arctic ecosystem in the absence of felid definitive hosts. |
format |
Text |
author |
Bouchard, Emilie Elmore, Stacey A. Alisauskas, Ray T. Samelius, Gustaf Gajadhar, Alvin A. Schmidt, Keaton Ross, Sasha Jenkins, Emily J. |
author_facet |
Bouchard, Emilie Elmore, Stacey A. Alisauskas, Ray T. Samelius, Gustaf Gajadhar, Alvin A. Schmidt, Keaton Ross, Sasha Jenkins, Emily J. |
author_sort |
Bouchard, Emilie |
title |
TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA |
title_short |
TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA |
title_full |
TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA |
title_fullStr |
TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA |
title_full_unstemmed |
TRANSMISSION DYNAMICS OF TOXOPLASMA GONDII IN ARCTIC FOXES (VULPES LAGOPUS): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA |
title_sort |
transmission dynamics of toxoplasma gondii in arctic foxes (vulpes lagopus): a long-term mark-recapture serologic study at karrak lake, nunavut, canada |
publisher |
DigitalCommons@University of Nebraska - Lincoln |
publishDate |
2019 |
url |
https://digitalcommons.unl.edu/icwdm_usdanwrc/2264 https://digitalcommons.unl.edu/context/icwdm_usdanwrc/article/3263/viewcontent/Bouchard_JWD_2019_TRANSMISSION_DYNAMICS.pdf |
long_lat |
ENVELOPE(-100.250,-100.250,67.250,67.250) |
geographic |
Arctic Nunavut Canada Karrak Lake |
geographic_facet |
Arctic Nunavut Canada Karrak Lake |
genre |
Arctic Fox Arctic Human health Nunavut Tundra Vulpes lagopus |
genre_facet |
Arctic Fox Arctic Human health Nunavut Tundra Vulpes lagopus |
op_source |
USDA Wildlife Services - Staff Publications |
op_relation |
https://digitalcommons.unl.edu/icwdm_usdanwrc/2264 https://digitalcommons.unl.edu/context/icwdm_usdanwrc/article/3263/viewcontent/Bouchard_JWD_2019_TRANSMISSION_DYNAMICS.pdf |
_version_ |
1782329919088361472 |