Telomere length is heritable and genetically correlated with lifespan in a wild bird
International audience Telomeres are protective caps at the end of eukaryotic chromosomes that shorten with age and in response to stressful or resource-demanding conditions. Their length predicts individual health and lifespan across a wide range of animals, but whether the observed positive associ...
Published in: | Molecular Ecology |
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Online Access: | https://hal.science/hal-03576754 https://doi.org/10.1111/mec.15807 |
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ftunivnantes:oai:HAL:hal-03576754v1 2023-05-15T15:56:19+02:00 Telomere length is heritable and genetically correlated with lifespan in a wild bird Vedder, Oscar Moiron, Maria Bichet, Coraline Bauch, Christina Verhulst, Simon Becker, Peter Bouwhuis, Sandra Institute of Avian Research Centre d'Études Biologiques de Chizé - UMR 7372 (CEBC) La Rochelle Université (ULR)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) Groningen Institute for Evolutionary Life Sciences Groningen (GELIFES) University of Groningen Groningen 2022 https://hal.science/hal-03576754 https://doi.org/10.1111/mec.15807 en eng HAL CCSD Wiley info:eu-repo/semantics/altIdentifier/doi/10.1111/mec.15807 hal-03576754 https://hal.science/hal-03576754 doi:10.1111/mec.15807 ISSN: 0962-1083 EISSN: 1365-294X Molecular Ecology https://hal.science/hal-03576754 Molecular Ecology, 2022, ⟨10.1111/mec.15807⟩ ageing biomarker birds heritability senescence telomeres [SDE]Environmental Sciences info:eu-repo/semantics/article Journal articles 2022 ftunivnantes https://doi.org/10.1111/mec.15807 2023-03-08T02:05:38Z International audience Telomeres are protective caps at the end of eukaryotic chromosomes that shorten with age and in response to stressful or resource-demanding conditions. Their length predicts individual health and lifespan across a wide range of animals, but whether the observed positive association between telomere length and lifespan is environmentally induced, or set at conception due to a shared genetic basis, has not been tested in wild animals. We applied quantitative genetic “animal models” to longitudinal telomere measurements collected over a 10-year period from individuals of a wild seabird (common tern; Sterna hirundo) with known pedigree. We found no variation in telomere shortening with age among individuals at the phenotypic and genetic level, and only a small permanent environmental effect on adult telomere length. Instead, we found telomere length to be highly heritable and strongly positively genetically correlated with lifespan. Such heritable differences between individuals that are set at conception may present a hitherto underappreciated component of variation in somatic state. Article in Journal/Newspaper Common tern Sterna hirundo Université de Nantes: HAL-UNIV-NANTES Molecular Ecology 31 23 6297 6307 |
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Open Polar |
collection |
Université de Nantes: HAL-UNIV-NANTES |
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ftunivnantes |
language |
English |
topic |
ageing biomarker birds heritability senescence telomeres [SDE]Environmental Sciences |
spellingShingle |
ageing biomarker birds heritability senescence telomeres [SDE]Environmental Sciences Vedder, Oscar Moiron, Maria Bichet, Coraline Bauch, Christina Verhulst, Simon Becker, Peter Bouwhuis, Sandra Telomere length is heritable and genetically correlated with lifespan in a wild bird |
topic_facet |
ageing biomarker birds heritability senescence telomeres [SDE]Environmental Sciences |
description |
International audience Telomeres are protective caps at the end of eukaryotic chromosomes that shorten with age and in response to stressful or resource-demanding conditions. Their length predicts individual health and lifespan across a wide range of animals, but whether the observed positive association between telomere length and lifespan is environmentally induced, or set at conception due to a shared genetic basis, has not been tested in wild animals. We applied quantitative genetic “animal models” to longitudinal telomere measurements collected over a 10-year period from individuals of a wild seabird (common tern; Sterna hirundo) with known pedigree. We found no variation in telomere shortening with age among individuals at the phenotypic and genetic level, and only a small permanent environmental effect on adult telomere length. Instead, we found telomere length to be highly heritable and strongly positively genetically correlated with lifespan. Such heritable differences between individuals that are set at conception may present a hitherto underappreciated component of variation in somatic state. |
author2 |
Institute of Avian Research Centre d'Études Biologiques de Chizé - UMR 7372 (CEBC) La Rochelle Université (ULR)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) Groningen Institute for Evolutionary Life Sciences Groningen (GELIFES) University of Groningen Groningen |
format |
Article in Journal/Newspaper |
author |
Vedder, Oscar Moiron, Maria Bichet, Coraline Bauch, Christina Verhulst, Simon Becker, Peter Bouwhuis, Sandra |
author_facet |
Vedder, Oscar Moiron, Maria Bichet, Coraline Bauch, Christina Verhulst, Simon Becker, Peter Bouwhuis, Sandra |
author_sort |
Vedder, Oscar |
title |
Telomere length is heritable and genetically correlated with lifespan in a wild bird |
title_short |
Telomere length is heritable and genetically correlated with lifespan in a wild bird |
title_full |
Telomere length is heritable and genetically correlated with lifespan in a wild bird |
title_fullStr |
Telomere length is heritable and genetically correlated with lifespan in a wild bird |
title_full_unstemmed |
Telomere length is heritable and genetically correlated with lifespan in a wild bird |
title_sort |
telomere length is heritable and genetically correlated with lifespan in a wild bird |
publisher |
HAL CCSD |
publishDate |
2022 |
url |
https://hal.science/hal-03576754 https://doi.org/10.1111/mec.15807 |
genre |
Common tern Sterna hirundo |
genre_facet |
Common tern Sterna hirundo |
op_source |
ISSN: 0962-1083 EISSN: 1365-294X Molecular Ecology https://hal.science/hal-03576754 Molecular Ecology, 2022, ⟨10.1111/mec.15807⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1111/mec.15807 hal-03576754 https://hal.science/hal-03576754 doi:10.1111/mec.15807 |
op_doi |
https://doi.org/10.1111/mec.15807 |
container_title |
Molecular Ecology |
container_volume |
31 |
container_issue |
23 |
container_start_page |
6297 |
op_container_end_page |
6307 |
_version_ |
1766391765873459200 |