Effect of ionizing radiation on the transcription levels of cell stress marker genes in the pacific oyster crassostrea gigas

• Published in: Radiation Research
• Main Authors: Farcy, E., Voiseux, C., Robbes, I., Lebel, J.-M., Fievet, B.
• Other Authors: Laboratoire de Radioécologie de Cherbourg-Octeville (IRSN/PSE-ENV/SRTE/LRC), Service de recherche sur les transferts et les effets des radionucléides sur les écosystèmes (IRSN/PSE-ENV/SRTE), Institut de Radioprotection et de Sûreté Nucléaire (IRSN)-Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), UMR 100 Physiologie et Ecophysiologie des Mollusques Marins, IFREMER, Site Expérimental d'Argenton, Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2011
• Subjects: chaperone; cobalt 60; cytochrome P450; glutathione transferase; heat shock protein 70; heat shock protein 90; messenger RNA; metallothionein; multidrug resistance protein; protein hsc72; superoxide dismutase; unclassified drug; animal experiment; article; biosensor; cell cycle regulation; cell stress; correlation analysis; Crassostrea gigas; detoxification; DNA sequence; gamma radiation; gene expression; ionizing radiation; morbidity; mortality; nonhuman; oxidative stress; oyster; priority journal; quantitative analysis; radiation dose; reverse transcription polymerase chain reaction; sensitivity analysis; thermoluminescence dosimetry; upregulation; Animals; Biological Markers; Cobalt Radioisotopes; Crassostrea; Dose-Response Relationship; Radiation; Gamma Rays; Laboratories; Radiometry; RNA; Messenger; Seawater; Stress; Physiological; Areva; Pacific; Pacific oyster
• Online Access: https://hal.science/hal-02954941; https://doi.org/10.1667/RR2525.1

In the North-Cotentin (Normandy, France), the marine environment is chronically exposed to liquid releases from the La Hague nuclear fuel recycling plant (Areva NC), resulting in a small increase in radioactivity compared to natural background. The transcriptional expression levels of stress genes w...